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Pharm Chp20
| Question | Answer |
|---|---|
| Define analgesia | is inhibition of the perception of pain or a condition in which the body is receiving painful stimulation, but the brain does not interpret the stimulation as pain. |
| Explain the term inflammation | a condition in which tissue have been damaged, characterized by swelling, pain, heat, and sometimes redness. |
| Joint pain | Arthralgia |
| Pain associated with muscle injury | Myalgia |
| Inflammation of joints | Arthritis |
| Small area of skin or mucous membrane that is discolored because of localized hemorrhages. | Petechia |
| Condition in which pain and inflammation of joints are accompanied by elevated body temperature | Rheumatic fever |
| Painful menstruation | Dysmenorrhea |
| Condition in which toxic doses of salicylates result in nausea, tinnitus and delirium. | Salicylism |
| What are the three major pharmacological effects produced by the Salicylates? | The three A’s associated with the pharmacological action of the salicylates are antipyresis, analgesia, and anti-inflammatory effects. |
| How do the non-opioid analgesics relieve pain? | Non-opiod analgesic inhibits the synthesis of prostaglandins and bradykinins, which are produced in response to an acute injury or chronic insult to tissue |
| Why do some people experience nausea and vomiting after taking aspirin? | Salicylates directly irritate the stomach mucosal lining |
| how do anti-inflammatory drugs interrupt the process of inflammation? | Drugs that reduce the inflammatory response stabilize cell membrane so that edema is lessened. |
| which anti-inflammatory drugs should not be administrated over long period of time? | , the acute treatment period with drugs such as indomethacin or naproxen is often limited because of the potential for intense gastric irritation. |
| Which of the following is pharmacologically considered an all around anti-inflammatory drug? | Ibuprophen |
| Cyclooxygenase (COX) is a family of enzymes that? | make various prostaglandins from arachidonic acid |
| Which of the following is correct about NSAIDS? | they are large class of anti-inflammatory drugs that inhibit more than one type of cycloocygenase (COX-1, 2) |
| Acetaminophen | is an aspirin substitute for analgesia and anitpyresis in aspirin sensitive patients |
| NSAIDS are | highly bound to plasma proteins |
| Which of the following is correct? | uriocsuric drugs can be given with hypouricmic drugs to lower uric acid concentrations |
| The COX-2 selective NSAIDS celecoxib (Celebrex) | is primarily an anti-inflammatory drug |
| Anti-inflammatory drugs. | vary in their ability to reduce all types of inflammation |
| Select all of the following that are part of the inflammatory process. | prostaglandins are released, Phagoctyes migrate to area,Vasodilation, proteins leak out of injured cells |
| Under which circumstances would non-opioid drugs be the appropriate treatment? | for acute postoperative pain |
| Which of the following is not a reason to choose acetaminophen? | for low GI irritation |
| Choose the reason why Prohenecid is useful in treating gout | enhances the renal excretion of uric acid |
| Select the indications for aspirin | analgesia, antipyresis, Anticoagulation |
| Gout Treatment | Allopurinol, Colchicine, Febuxostat, probenecid |
| Non-steroidal anti-inflammatory | Etodolac, Ibuprofen, Indomethacin, Naproxen |
Created by:
allisoncayetano