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Vet 228 "The Guide"

The Guide for the Care and Use of Laboratory Animals

QuestionAnswer
Laboratory Animal Any vertebrate animal produced for or used in research, testing, or teaching.
Animal Use The proper care, use, and humane treatment of laboratory animals produced for or used in research, testing, or teaching.
In 1959, Russell and Burch published what strategy? The Three R's.
What are the three R's? Replacement, Reduction, Refinement
Humane Care Actions taken to ensure that laboratory animals are treated according to high ethical and scientific standards.
Program The activities conducted by and at an institution that have a direct impact on the well-being of animals, including animal and veterinary care, policies and procedures, personnel and program management and oversight.
Institutional Officer The individual that bears ultimate responsibility for the Program.
Attending Veterinarian The Veterinarian responsible for the health and well-being of all laboratory animals used at the institution.
Institutional Animal Care and Use Committee (IACUC) Responsible for assessment and oversight of the institution's Program components and facilities.
PPE Personal Protective Equipment
Protocol Detailed description of the proposed use of laboratory animals.
Physical Restraint The use of manual or mechanical means to limit some or all of an animal's normal movement for the purpose of examination, sample collection, drug administration, therapy, or experimental manipulation.
Microenvironment The immediate physical environment surrounding the animal.
Macroenvironment The physical environment of the secondary enclosure.
Animal Activity Implies motor activity but also includes cognitive activity and social interaction.
Sanitation The maintenance of environmental conditions conducive to health and well-being. Involves bedding change, cleaning, and disinfection.
Cleaning Removes excessive amounts of excrement, dirt, and debris.
Disinfection Reduces or eliminates unacceptable concentrations of microorganisms.
Pest Control Programs designed to prevent, control, or eliminate the presence of or infestation by pests are essential in an animal environment.
Animal Biosecurity Includes all measures to control known or unknown infections in laboratory animals.
Quarantine The separation of newly received animals from those already in the facility, in a way that prevents potential spread of contaminants, until the health and possible the microbial status of the new animals have been determined.
Aseptic Technique Used to reduce microbial contamination to the lowest possible practical level.
Euthanasia The act of humanely killing animals by methods that induce rapid unconsciousness and death without pain or distress.
ILAR Institute for Laboratory Animal Research
Policies Practical statements of collective wisdom, convention, or management direction that are internal to the entity.
Procedures Detailed, step by step processes meant to ensure the consistent application of institutional practices.
USDA United States Department of Agriculture
What does the US Fish and Wildlife regulate? Importation/exportation of wild vertebrate and invertebrate animals and their tissues.
How often does the Guide require observations of an animal? At least daily.
GMA Genetically Modified Animal
 

 



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