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Med. Chem.

Med. Chem. Spring Final 2005

Drug NameChem ClassPharm ClassMOA
Cocaine Tropane derivative Local anesthetic/CNS stimulant Blocks Na channels/inhibits DA uptake
Benzocaine Aminobenzoic ester Local anesthetic Blocks Na channels
Procaine Aminobenzoic ester Local anesthetic Blocks Na channels
Tetracaine Aminobenzoic ester Local anesthetic Blocks Na channels
Butamben Aminobenzoic ester Local anesthetic Blocks Na channels
Propoxycaine Aminobenzoic ester Local anesthetic Blocks Na channels
Chloroprocaine Aminobenzoic ester Local anesthetic Blocks Na channels
Proparacaine Aminobenzoic ester Local anesthetic Blocks Na channels
Dibucaine Amide Local anesthetic Blocks Na channels
Bupivacaine Amide Local anesthetic Blocks Na channels
Lidocaine Amide Local anesthetic Blocks Na channels
Prilocaine Amide Local anesthetic Blocks Na channels
Mepivacaine Amide Local anesthetic Blocks Na channels
Etidocaine Amide Local anesthetic Blocks Na channels
Ropivacaine Amide Local anesthetic Blocks Na channels
Dyclonine Amino ketone Local anesthetic Blocks Na channels
Pramoxine Amino ether Local anesthetic Blocks Na channels
Fludrocortisone acetate Steroid Mineralocorticoid Mediates Na/K exchange-inc. Na reabsorbtion
Cortisone Steroid Systemic glucocorticoid Inhibits arachidonic acid release
Hydrocortisone Steroid Systemic glucocorticoid Inhibits arachidonic acid release
Corticosterone Steroid Systemic glucocorticoid Inhibits arachidonic acid release
Prednisone Steroid Systemic glucocorticoid Inhibits arachidonic acid release
Betamethasone Steroid Systemic glucocorticoid Inhibits arachidonic acid release
Dexamethasone Steroid Systemic glucocorticoid Inhibits arachidonic acid release
Clobetasol propionate Steroid Topical glucocorticoid Inhibits arachidonic acid release
Flucinolone acetonide Steroid Topical glucocorticoid Inhibits arachidonic acid release
Fluticasone propionate Steroid Topical glucocorticoid Inhibits arachidonic acid release
Triamcinolone acetonide Steroid Topical glucocorticoid Inhibits arachidonic acid release
Testosterone Steroid Androgen Testosterone agonist
Methyltestosterone Steroid Androgen Testosterone agonist
Fluoxymesterone Steroid Androgen/anabolic Testosterone agonist
Stanozolol Steroid Anabolic steroid Testosterone agonist
Oxandrolone Steroid Anabolic steroid Testosterone agonist
Nandrolone decanoate Steroid Anabolic steroid Testosterone agonist
Finasteride Steroid Androgen hormone inhibitor Inhibits 5a-reductase
Dutasteride Steroid Androgen hormone inhibitor Inhibits 5a-reductase
Estradiol cypionate Steroid Estrogen Estrogen agonsim
Estropipate Steroid Estrogen Estrogen agonism
Ethinyl estradiol Steroid Estrogen Estrogen agonism
Anastrozole Triazole Anti-estrogen Reversibly inhibits aromatase
Letrozole Triazole Anti-estrogen Reversibly inhibits aromatase
Exemestane Steroid Anti-estrogen Irreversibly inhibits aromatase
Clomiphene Stilbenediol Anti-estrogen Increases gonadotropin secretion
Tamoxifen Stilbenediol Anti-estrogen Rev. estrogen receptor antag.
Toremifene Stilbenediol Anti-estrogen Rev. estrogen receptor antag.
Raloxifene Misc. Anti-estrogen Sel. estrogen receptor modulator
Norethindrone Steroid Progestin Inhib. FSH/LH release
Norgestrel Steroid Progestin Inhib. FSH/LH release
Levonorgestrel Steroid Progestin Inhib. FSH/LH release
Desogestrel Steroid Progestin Inhib. FSH/LS release
Progesterone Steroid Progestin Progestin agonist
hydroxyprogesterone caproate Steroid Progestin Progestin agonist
Medroxyprogesterone acetate Steroid Progestin Progestin agonist
Megesterol acetate Steroid Progestin Progestin agonist
Mifepristone Steroid Antiprogestin Progestin antagonist
Tolbutamide Sulfonylurea Hypoglycemic Stimulates insulin release
Tolazamide Sulfonylurea Hypoglycemic Stimulates insulin release
Acetohexamide Sulfonylurea Hypoglycemic Simulates insulin release
Chlorpropamide Sulfonylurea Hypoglycemic Stimulates insulin release
Glyburide Sulfonylurea Hypoglycemic Simulates insulin release
Glipizide Sulfonylurea Hypoglycemic Stimulates insulin release
Glimepiride Sulfonylurea Hypoglycemic Simulates insulin release
Metformin Biguanide Hypoglycemic Increases glucose uptake
Acarbose Carbohydrate Hypoglycemic Inhibits a-glucosidase
Miglitol Carbohydrate Hypoglycemic Inhibits a-glucosidase
Rosiglitazone Thiazolidinedione Hypoglycemic Activate PPAR
Pioglitazone Thiazolidinedione Hypoglycemic Activate PPAR
Repaglinide Misc. Hypoglycemic Stimulates insulin release
Nateglinide Misc. Hypoglycemic Stimulates insulin release
Glucagon Peptide Glucose elevating agent Simulates glycogenolysis
Diazoxideoral Benzothiadiazine Glucose elevating agent Inhibits insulin release
Sulfadiazine Sulfonamide Antibacterial Inhibits dihydropteroate synthase
Silver sulfadiazine Sulfonamide Antibacterial Inhibits dihydropteroate synthase
Sulfasalazine Sulfonamide Antibacterial Inhibits dihydropteroate synthase
Sulfisoxazole Sulfonamide Antibacterial Inhibits dihydropteroate synthase
Sulfamethoxazole Sulfonamide Antibacterial Inhibits dihydropteroate synthase
Trimethoprim Pyrimidinediamine Antibacterial Inhibits dihydrofolate reductase
Nalidixic acid Quinolone Antibacterial Inhibits DNA gyrase
Cinoxacin Quinolone Antibacterial Inhibits DNA gyrase
Norfloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Ciprofloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Ofloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Lomefloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Enoxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Levofloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Sparfloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Gatifloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Moxifloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Trovafloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Alatrovafloxacin Fluoroquinolone Antibacterial Inhibits DNA gyrase
Amantadine Adamantane Antiviral Inhibits host cell penetration by virus
Rimantadine Adamantane Antiviral Inhibits viral uncoating
Oseltamivir Misc. Antiviral Inhibits neuraminidase
Zanamivir Misc. Antiviral Inhibits neuraminidase
Ribavirin Pryimidine nucleoside Antiviral Inhibits viral DNA polymerase
Amprenivir Misc. Antiviral Protease inhibitor
Saquinavir Misc. Antiviral Protease inhibitor
Indinavir Misc. Antiviral Protease inhibitor
Ritonavir Misc. Antiviral Protease inhibitor
Nelfinavir Misc. Antiviral Protease inhibitor
Abacavir Purine nucleoside Antiviral Comp. inhibits HIV-1 reverse transcriptase
Didanosine Purine nucleoside Antiviral Comp. inhibits HIV-1 reverse transcriptase
Lamivudine Pyrimidine nucleoside Antiviral Comp. inhibits HIV-1 reverse transcriptase
Stavudine Pyrimidine nucleoside Antiviral Comp. inhibits HIV-1 reverse transcriptase
Zalcitabine Pyrimidine nucleoside Antiviral Comp. inhibits HIV-1 reverse transcriptase
Zidovudine Pyrimidine nucleoside Antiviral Comp. inhibits HIV-1 reverse transcriptase
Delavirdine Misc. Antiviral Non-comp. inhibits HIV-1 reverse transcriptase
Efavirenz Misc. Antiviral Non-comp. inhibits HIV-1 reverse transcriptase
Nevirapine Misc. Antiviral Non-comp. inhibits HIV-1 reverse transcriptase
Acyclovir Purine nucleoside Antiviral Inhibits viral DNA polymerase
Vidarabine Purine nucleoside Antiviral Inhibits viral DNA polymerase
Famciclovir Purine nucleoside Antiviral Inhibits viral DNA polymerase
Valacyclovir Purine nucleoside Antiviral Inhibits viral DNA polymerase
Ganciclovir Purine nucleoside Antiviral Inhibits viral DNA polymerase
Trifluridine Pyrimidine nucleoside Anitviral Inhibits thymidylate synthetase
Foscarnet sodium Phosphate Antiviral Inhibits viral DNA polymerase
Created by: kdsimmo1