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arbo viruses that are near invasive
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what are the characteristics of a brain abscess
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micro
CNS infections
| Question | Answer |
|---|---|
| arbo viruses that are near invasive | west nile, eee, wee and california (la cross ) are nationally notifiable |
| what are the characteristics of a brain abscess | |
| what is a brain abscess | focal infection of the brain parenchyma that can be caused by bacteria fungi or parasites |
| what is common of a bacterial infection that causes an abscess | it would be a mixed bag of microbes usually representative of bacteria found in the mouth |
| what are the common etiologies of a brain abscess | streptococcus, pseudomonas, staphylococci, prevotella, bacteroides, fusobacterium, propionibacterium, peptostreptococcus, enterobactericeae, mycobacteria, cryptococcus neoformans |
| characteristics of streptococcus | gram positive coccus |
| characteristics of pseudomonas | gram negative, aerobic, rods, polar flagulated |
| characteristics of staphylococci | gram positive, cocci |
| characteristics of prevotella | gram negative |
| characteristics of bacteroides | obligately anaerobic, gram negative rod |
| characteristics of fusobacterium | obligately anaerobic gram negative fusiform |
| characteristics of propionibacterium | gram positive rod |
| characteristics of peptostreptocoous | anaerobic, gram positive, non spore forming, cocci |
| characteristics of enterobactericeae | gram negative, rod, facultatively anaerobic |
| characteristics of mycobacteria | aerobic, non motile, gram positive |
| characteristics of cryptococcus neoformans | encapsulated yeast, stains gram positive, india pink ink used for visualization in spinal fluid |
| what are the three cellular pathways that can be used to cross the BBB | paracellular, transcellular and the trojan horse mechanism |
| describe the transcellular pathway | penetration vis a receptor mediated endocytosis or macropinocytosis, characterized by cytoskeletal rearrangements at the area of bacterial interaction with the host cell membrane |
| describe paracellular pathway | entry due to increased BBB permeability usually due to opening of tight junctions or of increased pinocytotic activity and the formation of transendothelial channels |
| desirous the trojan horse mechanism | transmigration with infected leukocytes |
| what microbes utilize transcellular pathway | E. coli (receptor), GBS, Listeria monocytogenes, streptococus pnemoniae (receptor), candida albicans, cryptococcus neoformans, HIV |
| what microbes utilize paracellular pathway | borelia burgdoferi, treponema pallidum |
| what microbes use the trojan horse (infected leukocyte) pathway | HIV, SIV |
| what is encephalitis | infection of the cerebral cortex, usually viral two major categories, human to human and zoonotic (animal contact) |
| etiologies of human to human encephalitis | HSV-1, HSV-2, VZV, CMV, influenza, HIV |
| etiologies of zoonotic encephalitis | arbovirus, rabies |
Created by:
tpodbilski