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immunology chapter9,
immunology
| Question | Answer |
|---|---|
| which of the following is a test for antibody to specific antigen | RAST |
| in performing blood typing using the tube method,if the red cell button is not resuspended properly,what are the most likely results | false-positive |
| in a sandwich or capture assay to determine the presence of a viral antigen in a patient sample which of the following would be on the solid phase | untagged or unlabeled |
| type II hypersensitivity could involve all of the following | HDN,AHA,Transfusion rejection |
| If a coombs test is positive what does that mean | an invetro test ned to be done to check binding of rbcs |
| T-cell dependant hypersensitivity occurs in how many hours | 48-72 hours |
| which isotope of immunoglobulin is involved in type I hypersensitivity | IGE |
| in an indirect fluorescent immunoassay such as the FTA confirmatory test for syphilis what is true | amount of fluorscence is directly proportional to amount of patient antibody and its more sensitive |
| pregnancy testing is based on an early increase of which hormone | HCG |
| the principle difference between type II and type III hypersensitivity reactions is | type II free antibody reacts with antigen on cell surface(cellular antigens),type III antibody reacts with soluble antigens |
| to determine if a patient is allergic to peanuts what is the best test to perform | RAST |
| patient serum+labeled ag+known ab are added together,incubated and unbound material is washed off.what test is being performed | competitive immunoassay |
| which of the following best describes homogeneous assays | no seperation step,directly proportioned |
| which of the following best describes competitive binding assays | radioanalytes being detected competes with radiolabeled analyte for a limited # of binding sites |
| An example of a type III hypersensitivity is | autoimmune diseases,arthus,serum sickness,sle |
| a positive DAT test might indicate which of the following | HDN,AHA,transfusion rejection |
| 5 year old girl was rushed to er trouble breathing.she most likely has | Anaphylaxis,type I hypersensitivity |
| which antibody class may require the use of an enhancement technique to visualize the reaction | IgG |
| a hypersensitivity reaction characterized by the presence of IgG that reacts with soluble antigen best describes | III |
| which of the following diseases is an example of type II hypersensitivity | HDN,AHA,transfusion rejection,good pastures |
| reaction to poison ivy is which type of hypersensitivity | IV |
| anaphylactic reactions are mediated by | IgM mast cells |
| components of a competitive immunoassay include what | all reactants are mixed together simutanously,labeled antigens compete with unlabeled patient antigen for binding sites |
| a serological reaction is set up in which the antigen is bound to a large carrier,the antibody is soluble and they bind and form an insouble complex that is detected macroscopically.what type of assay is described | Agglutination |
| anaphylaxis is characterized by what | bronchospasm,edems,skin manafestations,vascular congestion |
| a serological test that uses red blood cells coated with exogenous antigens | hemoagglutination |
| the radioimmunosorbant assay can be used for the diagnosis of which type of hypersensitivity | immediate or type I |
| what test would determine hemolytic disease of the newborn | DAT |
| precipitation of immune complexes in small blood vessels under the skin that occurs when antigen is injected into an animal with large amounts of circulating antibody describes which of the following | arthus phenomenon |
| the immune mechanism involved in contact dermatitis is which of the following | synthesized cytotoxic t cells |
| cold autoimmune hemolytic anemia is an example of which type of hypersensitivity | II |
| the ppd reaction to determine exposure to tuberculosis is based on which of the following | sensitized t cells |