Decline in a muscle's ability to maintain a constant level of force or tension after prolonged, repetitive stimulation. The failure of a muscle to produce tension b/c of previous contractile activity

When a skeletal muscle fatigues, what happens to the contractile force over time?

The contractile force declines due to previous contractile activity Once the muscle has reached max tetanic tension, there is no longer an increase in force. At this stage the muscle becomes fatigued and contractile force starts to decrease over time

What are some proposed causes of skeletal muscle fatigue?

The buildup of lactic acid, ADP, and Pi in the muscle fibers. One other reason comes from Calcium levels decreasing from muscle contractions.

List a few ways that humans could delay the onset of fatigue when they are vigorously using their skeletal muscles. In exercising people could delay the onset of fatigue by:

Doing multiple sets of low repetition exercise. Allowing for multiple times of rest periods/ Healthy Diet, along with adequate exercise. (Frequent exercise creates endurance, and endurance resists fatigue.)

The term tetanus refers to

sustained muscle tension due to repetitive stimuli.

During fatigue what happens to the cross bridges & rate of stimulus delivery?

the number of active cross bridges begins to decline although the rate of stimulus delivery (frequency) remains constant.

If an intervening rest period is imposed on active skeletal muscle, what happens?

The development of fatigue will be delayed.

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PhysioEx2Activity5

Fatigue in Isolated Skeletal Muscle

Question	Answer
Describe fatigue	Decline in a muscle's ability to maintain a constant level of force or tension after prolonged, repetitive stimulation. The failure of a muscle to produce tension b/c of previous contractile activity
When a skeletal muscle fatigues, what happens to the contractile force over time?	The contractile force declines due to previous contractile activity Once the muscle has reached max tetanic tension, there is no longer an increase in force. At this stage the muscle becomes fatigued and contractile force starts to decrease over time
What are some proposed causes of skeletal muscle fatigue?	The buildup of lactic acid, ADP, and Pi in the muscle fibers. One other reason comes from Calcium levels decreasing from muscle contractions.
List a few ways that humans could delay the onset of fatigue when they are vigorously using their skeletal muscles. In exercising people could delay the onset of fatigue by:	Doing multiple sets of low repetition exercise. Allowing for multiple times of rest periods/ Healthy Diet, along with adequate exercise. (Frequent exercise creates endurance, and endurance resists fatigue.)
During cross bridge cycling in skeletal muscle, force is created by what?	Power stroke of myosin heads
The term tetanus refers to	sustained muscle tension due to repetitive stimuli.
During fatigue what happens to the cross bridges & rate of stimulus delivery?	the number of active cross bridges begins to decline although the rate of stimulus delivery (frequency) remains constant.
If an intervening rest period is imposed on active skeletal muscle, what happens?	The development of fatigue will be delayed.

Created by: meunid

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