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P140 Final
Ch. 21-23
| Question | Answer |
|---|---|
| Excedrin is an example of salicylate combined with | caffeine |
| The use of which of the following agents during viral infections in children may increase the incidence of Reye syndrome | aspirin |
| Which of the following drugs is only a nonopioid analgesic and snitpyretic | acetaminophen |
| The opioid receptors are located in which of the following parts of the nervous system | A and B (brain & spinal cord) |
| Pinpoint pupils, insomnia, and agitation are signs of overdose with which of the following | morphine |
| Opioid antagonists include all of the following , except | naftifine |
| All of the following foods contain salicylates, except | bananas |
| Acetaminophen can be substituted for aspirin to treat mild to moderate pain or fever for all of the following patients, except | those who are at risk for Reye syndrome |
| Which of the following COX-2 inhibitors was removed from the US market in 2004 due to increased risk of cardiovascular event | rofecoxib |
| Which of the following NSAIDs is available in parenteral form | ketorolac |
| Celecoxib is used as an | analgesic |
| Which of the following is the greatest threat from morphine poisoning | respiratory depression |
| The anti-inflammatory action of aspirin is due to | inhibition of prostaglandin formation |
| Ketoprofen is considered a | NSAIDs |
| Which of the following opioids is available for rectal administration | hydromorphone |
| Salcylates increase the risk of gastrointestinal ulceration with which of the folowing drugs | A and C (corticosteroids and alcohol) |
| Chronic ingestion of which of the following agents may cause reduction of white blood cells, liver damage in alcoholics, or renal damage | acetaminophen |
| Which of the following is principally synthesized from arachidonic acid(lipids) by enzyme COX | interferon |
| All of the following narcotic analgesics should be avoided during pregnancy or labor, except | oxycodone |
| Which of the following opioid antagonist is available in oral form | naltrexone |
| Anacin is an example of salicylate which is combined with | coffee |
| The salicylates are contraindicated in pregnancy (category C), but aspirin during pregnancy is listed as category | D |
| Tolmetin, sulindac, and celecoxib are available in the US. These agents are classified as the | NSAIDs |
| Most NSAIDs are used for arthritis, osteoarthritis, dysmenorrhea, and ____ pain | muscle |
| Narcotic analgesics are classified as Schedule II drugs, except for ____, which is classified as a Schedule I drug | heroine |
| Pure opioid antagonists such as nalxone are able to block both MU and ____ receptors | Kappa |
| Anti-migraine drugs include the triptans and the ergot ____ | alkaloids |
| A natural or synthetic narcotic substance is referred to as an ___ | opioid |
| Aspirin is absorbed rapidly from the duodenum and the ____ | stomach |
| Many NSAIDs are safe and produce adverse effects only at ______ | high doses |
| Which of the following organisms are ultra microscopic, lack rigid cell walls, and are considered to be the smallest free-living organisms | mycoplasms |
| Any anitibiotic that is administered for a long time may result in which of the following | superinfections |
| Which of the following anti-infective agents were the first drugs to prevent and cure human bacterial infections successfully | penicillins |
| Cephalosporins are known as | beta-lactam antibiotivs |
| Sulfonamides suppress bacterial growth by triggering a mechanism that blocks synthesis of | folic acid |
| Which of the following agents may cause the risk of crystals and stones forming in the kidneys | sulfonamides |
| The major cause of resistance to penicillin is due to production of | penicillinases |
| Injection of penicillin to a patient may cause anaphylactic reactions with how long after administration | 30 minutes |
| Resistant penicillins are used predominantly for penicillinase-producing microorganisms of which of the following types of infections | staphylococcal infections |
| Extended spectrum penicillins are prescribed mainly to treat serious infections caused by | gram-negative organisms |
| Major aminoglycosides include all of the following ecept | vancomycin |
| Macrolide derivatives include all of the following except | clindamycin |
| Which of the following are the drugs of choice for the treatment of Mycoplasma pneumoniae, Legionnaires' disease, and pertusis | macrolides |
| Which of the following are the drugs of choice for rickettsial conditions such as Rocky Mountain spotted fever | tetracycline |
| Which of the following is the drug of choice for treating leprosy | dapsone |
| Fluoroquinolones are related to which of the following acids | nalidixic acid |
| Which of the following agents may lead to Gray Baby Syndrome in neonates | chloramphenicol |
| Which of the following is an example of fluoroquinolones | ciprofloxacin |
| Which of the following agents may cause rash on the upper body that is sometimes called "Red-Man Syndrome" | vancomycin |
| Extended-spectrum penicillins are bactericidal and inhibit bacterial _____ synthesis | cell wall |
| The cephalosporins are classified into four different______ | generations |
| Aminoglycosides cancan cause serious adverse effects such as ototoxicity and _____ | nephrotoxicity |
| In patients with penicillin allergy, _____ are the best alternatives in the treatment of gonorrhea, syphilis, and pneumococcal pneumonia | erythromycins |
| ______ is highly effective in prophylaxis of "traveler's diarrhea" | Doxycycline |
| Fluoroquinolones are used in the treatment of infections caused by Gram-positive and ______ microorganisms | Gram-negative |
| Chloramphenicol can cause suppression of ____ (in high doses) with resulting pancytopenia | bone marrow |
| Clindamycin may cause nausea, vomiting, diarrhea, and pseudomembranous _____ | colitis |
| Dapsone is excreted in breast milk, and may cause _____ reactions in neonates | hemolytic |
| Ethambutol may cause optic ____, drug fever, hallucinations, and joint pain | neuritis |
| Sulfadizine | microsulfan |
| carvenicillin | geocillin |
| cefdinir | ominecef |
| sulfisoxaole | gantrisin |
| ceftraxone | recephin |
| cephalexin | keflex |
| The genetic information of viruses includes which of the following | either DNA or RNA |
| Which of the following is an example of emerging viruses that threaten the public health and may kill thousands of people each year | dengue virus |
| Acyclovir is most effective against which of the following viruses | herpes simplex virus |
| Famciclovir is used for the management of which of the following viral disorders | herpes zoster (shingles) and genital herpes |
| amantadine is used for which of the following disorders | influenza A |
| Which of the following agents is a nonnucleoside reverse transcriptase inhibitor that prevents replication of HIV_1 virus | delavirdine |
| Lamivudine is in which of the following classes of drugs used to treat HIV infection in patients with AIDS | nucleoside reverse transcriptase inhibitors |
| Ritonavir is an example of the | PIs |
| The fungi are a distinct group of organisms that are | neither plants nor animals |
| Amphotericin B acts by binding to fungal | cell membranes |
| Which of the following is the most serious adverse effect of amphotericin B | hypotension |
| Griseofulvin is available for which of the following routes of administration | only the topical form |
| Vaginal tablets of nystatin are contraindicated in which of the following conditions or disorders | pregnancy and vaginal infections caused by Trichomonas specias |
| Ketoconazole is used for severe systemic fungal infections including | candidiasis (oral thrush) |
| Griseofulvin is effective in which of the following fungal infections | mycotic skin infections |
| Which of the following is classified as an anti-protozoal | metonidazole |
| Itraconazole is an antifungal indicated in the treatment of which of the following infections | all of the above (blastomycosis; histoplasmosis; apergillosis) |
| Which of the following agents is an antimalarial | primaquine |
| Chloroquine is the drug of choice to treat acute malaria attacks resulting from which of the following plasmodium | P.falciparum |
| Griseofulvin is classified as | an antifungal |
| The process of copying the genetic material is referred to as ______ | replication |
| Some animal viruses are responsible for diseases such as hemorrhagic fever caused by _____ virus | ebola |
| "Immunocompromised" means impairment of the _____ _______ | immune system |
| Amantadine is an antiviral and anticholinergic agent effective against influenza A and _____ disease | Parkinson's |
| Ganciclovir should not be administered during pregnancy because of its _____ potential | carcinogenic |
| Missing a single dose of HAART medication even twice a week can cause the development of drug-resistant _____ | HIV |
| Lamuvidine is used for HIV infection in combination with _____ | zidovudine |
| Fungi infections include athlete's foot, histoplasmosis, cryptococcosis, tinea, and _____ infections | candida |
| Amphotericin B for parenteral use should only be mixed in _____ | D5W |
| Chloroquine is the drug of choice to suppress ____ symptoms | malaria |