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Histology
Chapter 5 Epithelial Tissue II
| Question | Answer |
|---|---|
| Epithelial cells exhibit a distinct polarity which means they have an ____ domain, a _____ domain, and a ______ domain. | Apical Lateral Basal |
| The _____ domain is always directed toward the exterior surface or the lumen of an enclosed cavity or tube. | Apical |
| The _____ domain communicates with adjacent cells and is characterized by specialized attachment sites. | Lateral domain |
| The _____ domain rests on the basal lamina anchoring the cells to underlying connective tissue. | Basal domain |
| The apical domain is capable of having what 3 cytoplasmic processes? Define each of the 3. | Microvilli - cytoplasmic process that extend from the cell surface. Stereocilia (Sterovilli) - really long microvilli.(**STEREOCILIA WILL BE ON EXAM) Cilia - motile cytoplasmic processes. |
| The ____ and ____ of microvilla correlate closely with the cells absorptive capacity. | Number and shape |
| Microvilli contain ______ filaments anchored to _____ in teh top of the microvillus. | Actin. Villin. |
| The _____ filaments extend down the microvillus where they interact w/ horizontal actin filaments of the ______ _____ at the base of the microvillus. | Actin. Terminal Web. |
| The actin filaments are crosslinked by _____ and _____ to give rigidity. | Fascin and Fimbrin |
| What binds the actin filaments to the plasma membrane of the microvillus? | Myosin I |
| Stereocilia is very rare; seen only in _____, proximal portions of the ______ ______ and hair cells of the _____ _____. | Epididymus. Ductus Deferens. Inner Ear. |
| Like microvilli, _____ are supported internally by actin crosslinked by _____. | Stereocilia. Fibrin. |
| Stereocilia also contain a plasma membrane associated molecule called _____. | Erzin |
| The stem portion and apical protrusion of stereocilia contain ______. | alpha-actinin |
| Hair cells of the inner ear lack both _____ and _____. | Erzin and alpha-actinin |
| Cilia arms contain _____ _____, a microtubule associated motor protein. | Ciliary Dynein |
| What is the source of energy for ciliary movement? | ATP |
| The lateral surface of cells may form folds and invaginations that create ______ _____, somewhat like tongue-and-groove margins or a jigsaw puzzle. | Interdigitating Margins |
| Epithelial cells are extremely adherent to each other (CAMSs) and ______ ______ _______ are necessary to seperate tehm. | Strong Mechanical Forces. (CAMs - cell adhesion molecules) |
| What are the 4 types of cell junctions? | Zona Occludens, Zona Adherens, Desmosomes or Macula Adherens, and Gap Junctions. (**EXAM QUESTION ON GAP JUNCTIONS) |
| What cell junction type forms a band or seal that completely encircles the cell? This cell junction type is sometimes referred to as what? | Zona Occludens. Tight Junctions. |
| What type of cell junction completely encircles the cell? It allows _____ of one cell to the next. | Zona Adherens. Adhesion. |
| A ____ is a disk-shaped structure at the lateral surface of one cell that is matched with an identical structure on the surface or a neighboring cell. | Desmosome (Macula Adherens). (like spot welds b/w cells; very strong) |
| Communicating junction, also called _____ _____ are the only cellular structure that permit the direct passage of ______ ______ from one cell to the other. | Gap Junctions. Signaling Molecules. |
| Each unit of a gap junction is known as a _____; formed by ______ units called _____. | Connexon. Six Units. Connexins. |
| What type of gating mech. are responsible for closing and opening the cytoplasmic domains of gap junction channels? | Calcium-Independent. Gating mechanisms. |
| A mutation encoding connecin-26 (Cx26) causes what? | Congenital Deafness |
| The basal domain of epithelial cells is characterized by what 3 specializations? | Basement Membrane. Cell-to-Extracellular Matrix Junctions. Basal Cell Membrane Infoldings. |
| ______ ______ is a specialized structure located next to the basal domain of epithelial cells and the underlying connective tissue. | Basement Membrane. |
| A hemidesmosome is an example of what type of basal cell specialization? | Cell-to-Extracellular Matrix Junction |
| Which basal domain specialization increases cell surface area and facilitates interactions b/w adjacent cells and extracellular matrix proteins? | Basal Cell Membrane Infoldings |
| At the contact zone of epithelial cells and the basal lamina what can be found? Their form can be described as _____ of a ______. | Hemidesmosomes. Half Desmosome (**VERY POSSIBLE EXAM Q) |
| What is the autoimmune disease in which antibodies are directed against a particular antigen (protein) in hemidesmosomes? | Bullous pemphigoid. |
| The terms Basal lamina and basement membrane are used ______ and ______. | Interchangeable. Inconsistently. |
| The interface b/w epithelium and connective tissue is known as the _____ _____. | Basal Lamina |
| This term, which originated in light microscopy, is used only to apply to epithelium. | Basement Membrane. |
| A connective tissue that supports, binds epithelium to nearby structures and provides nourishment to the epithelium is known as what? | Lamina Propria. |
| The PAS method is used to stain _____ ______ in intestinal glands of the colon; H&E staining is used to stain the same membrane of the trachea. | Basement Membrane (**SEE LAST SLIDE OF EPITHELIUM II PACKET - SLIDE IS "VERY PRETTY" - POSS EXAM Q). |
| Chapter 5: Epithelial Tissues II |
Created by:
kentukred