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Hematology1-5
quiz
| Question | Answer |
|---|---|
| what is the average diameter of a normal erythrocyte? | 7-8 nm |
| what disease state can be associated with the presence of tissue neutrophils in bone marrow? | Myelocytic leukemia |
| which cell in the granulocytic series is present in greatest percentages in normal bone marrow? | band neutrophil |
| where does T-cell differentiation take place? | thymus |
| the stage in granulocyte maturation where the nucleus appears kidney shaped is evident in what cell? | metamyelocyte |
| By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as: | infection, bleeding, hyopoxia |
| reactive lymphocytes are present in the evaluation of certain diseases such as: | infectious mononucleosis |
| the maturation of the granulocytic series is characterized by | decrease in nuclear volume, appearance and disappearance of primary granules, nuclear chromatin clumping, cytoplasmic color change from blue to pink appearance of secondary granules |
| the lymphoblast can be identified morphologically by what characteristics? | large round nucleus, basophilic cytoplasm, nucleoli |
| what percentage of erythrocytes is functional in peripheral blood after release from the bone marrow | 100% |
| Plasmacytes represent the end stage of what cell lineage? | lymphocytes |
| which of the following is the largest hematopoietic cell in the bone marrow? | megakaryocyte |
| what stages do both basophils and eosinophils pass through in their sequence of maturity? | Myelocyte, metamyelocyte, band cell, segmented cell |
| Evaluate the clinical use of interleukins | wound healing, activating lymphocytes, assisting in growth of bone marrow |
| the hematopoietic system consists of the | thymus, bone marrow, liver, spleen |
| what is the sequence of maturity for the erythrocyte? | Rubriblast, prorubricyte, rubricyte, metarubricyte, reticulocyte, erythrocyte |
| the platelet structure is composed of | Peripheral zone, Sol-gel zone, Organelle zone |
| platelet membrane glycoprotein Ib is the receptor for __________, which serves to mediate the adhesion of platelets to subendothelium | von Willebrand factor |
| which of the following include specificity of plasma membrane receptors within the peripheral zone?> | ADP, Thrombin, Glycoprotein IIa, Serotonin |
| all of the following are major systems involved in maintaining hemostasis EXCEPT | Kinin system |
| The organelle zone is composed of | Alpha granules, Dense granules, Lysosomes, Glycogen |
| What characteristics are helpful in the identification of monocytes? | gray-blue cytoplasm, digestive vacuoles, lacy, delicate chromatin and indented nucleus, ground-glass appearnce of cytoplasm with evenly distributed fine granules |
| which constituent of the peripheral zone contain glycoproteins responsible for blood group specificity(ABO), tissue compatibility [human leukocyte antigen (HLA)], and platelet antigenicity? | Glycocalyx |
| Primary hemostasis is defined as: | The interaction of platelets and the vascular wndothelium in halting bleeding following vascular injury |
| what is the function of tissue thromboplastin in maintaining vascular integrity? | initiates fibrin formation through the extrinsic pathway of the coagulation system. |
| ________ is a reversible process whereby platelets stick to a foreign surface | adhesion |
| what is the normal platelet count? | 150,000 to 400,000/uL |
| Platelet factor4 (PF4) neutralizes which anticoagulant? | heparin |
| activation of platelets results in which of the following? | stickiness, adhesion, shape change, aggregation |
| The platelet membrane represents a fluid lipid bilayer composed of | glycoproteins, glycolipids, lipoproteins |
| the clear zone of cytoplasm that surrounds a higher stained granulomere is termed | Hyalomere |
| what is the function of tissue plasminogen activator (TPA)? | activates plasminogen to plasmin and lyses the fibrin clot |
| The peripheral blood, approximately _______ percent of the platelets are sequenstered in the spleen as functional reserves. | 30% |
| what major contractile protein in the platelet cytosol accounts for 20-30% of total platelet protein and functions within microtubules in organizing parallel filaments capable of contraction? | actin |
| the average diameter of the platelet is | 2-4 nm |
| the organelle region is responsible for the ______ activities of the platelet | metabolic |
| Hemorrgaging from veins results in large, ill-defiend, soft tissue bleeding termed | Ecchymoses |
| which substance induces dense and alpha granule secretion? | Thromboxane A2 (TXA2), ADP, Epinephrine, Thrombin |
Created by:
hiroko2014