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compounding
quiz
| Question | Answer |
|---|---|
| act of reducing a substance to small, fine particles | comminution |
| to scatter or incorporate the particles of one substance into another | dispense |
| the act of dissolving a substance into a liquid | dissolution |
| a sweetened hydroalcoholic solution which may contain an active ingredient or serve as a vehicle for another medication; binder/filler to mask the actual taste of the medication | Elixir |
| A mixture of two liquids that are not soluble in each other. when shaken, one phase will form globules in the other. | Emulsions |
| inert substances added to another substances in order to attain suitable consistency, shape or form (tablets fillers and binders | excipients |
| used to combine one drug with another in a mortar and pestle.place the smaller amount, usually the active ingredients into mortar then add the same amount of the next ingredient | geometric dilution |
| a water loving substance | hydrophilic |
| water hating or oil loving substance | hydrophobic |
| using a spatula to mix, smooth, or dispense a solid, semisolid, or liquid into an ointment base | levigation |
| a semisolid dosage with a petroleum or fatty bee meant for topical application | ointment |
| substances added that are intended to maintain sterility by killing or inhibiting growth of bacteria or other organism | preservatives |
| method for filling capsules in which the body of a capsule is repeatedly punched into a cake of medication until the capsule is full | punch method |
| a liquid dosage form in which active ingredient are dissolved in a liquid vehicle | solution |
| to add slowly | sprinkle |
| mixing a substance using a stir rod or other appropriate tool, without the use of a stir bar | stir by hand |
| mixing or agitation a substance using a stir bar and magnetic stir function of the hot plate | stirring |
| surface acting agent. a substance used to lower the surface tension of a liquid to facilitate compounding | surfactant |
| insoluble substance held in dispersion by an agent to prevent separation or settling | suspension |
| controlled sucrose solution suitably flavored and intended as a vehicle or base or the active ingredient. Must be preserved with an antibacterial anti fungal ingredient | syrup |
| to reset the balance to zero | tare |
| grinding or mixing dry powders in a mortar and pestle to reduce particle size | trituration |
| a whorled arrangement, design, or pattern created by the spin bar and the magnetic stir function of the hot plate | vortex |
| two pan balance, used weight small amounts | class III prescription balance |
| two pan balance, used for larger weights | counterbalance |
| single pan, easier to operate than two pan balance, more accurate | digital electronic balance |
| used with two-pan balances to offset ingredients weight; made of polished brass with noncorrosive coating | pharmaceutical weights |
| used to transfer solid ingredients to weighing pans, ointments and creams, remove material from mortar pestle | spatulas |
| glass | stirring rod |
| used for grasping objects; used with pharmaceutical weights to avoid transferring moisture or oil from hands | forceps |
| plate made of ground glass; disposable nonabsorbent parchment paper | compounding slab |
| used in measuring liquids; | used to measure liquid |
| used for grinding and mixing ingredients | mortar and pestle |
| used for storing ingredients and final products | freezers and refrigerators |
| protection when working with powders | container hood, mask, and gowns |
| used for combining tablet ingredients | tablet press |
| used for making larger quantities of capsules | capsule machine |
| other equipment | tong, hot plate, ointment jar, troche mold, suppository mold, thermometer, braun, homogenizer |
| Many compounding pharmacy seek national accreditation | protects patient, protect business, differentiate their practice from other pharmacies |
| responsible for accrediting pharmacies | PCAB |
| to be accredited must follow all specific standards | 1.must follow continuous quality improvement process including periodic spot checks, random selection of product to be analyzed at an outside lab 2. certification of pharmacy technician |
| certification of pharmacy technician in compounding | 1. pass PTCB; 2. complete mini-certifications and laboratory training; 3. all compounding task must be supervised and checked by the pharmacist. |
| USP chapter 795 | only USP or National formulary ingredients should be used; pharmacist balance cost of ingredients with quality;3. pharmacist must have multiple sources of ingredients |
| Material Safety Data Sheet must be filed with for all stored ingredients; contain information on: | 1. hazard and flammability, how to clean up spills, procedures for treating accidental ingestion or exposure |
| estimated for beyond-use dating | refrigerated solutions: 14 days solids and solutions: 6 months or less; all other formulations: 30 days |
| * if using other ingredients and may expire sooner than 6 months, that will be the expiration date | |
| manufactured or bulk materials | 25% of the remaining expiration date; 6 months earlier |
| a patient-specific medication prepared on-site by the technician, under the supervision of the pharmacist, from individual ingredients | compounded preparations |
| products prepared off-site by a manufacturer, mass production | manufactured products |
| recipe for maing the compound prescriptions | master control record - prepared by pharmacist or compounding service |
| master control record list: | drug's name, strength, dosage form, ingredients and quantities, mixing instructions, recommended beyond use dating, storing and labeling requirements |
| ff | |
| generated foe each prescription; use by pharmacist to complete initial calculation and documenting them | compounding log; |
| copy of the log | prescription record |
| compounding log list | ingredients, manufacturer, wholesaler source, assigned lot number, NC number, expiration date of ingredients; quantity made, date of compounding, initials of pharmacist and compounding technicians |
Created by:
luvufaever