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MedChem Exam 1 Drugs

Spring Semester 2005

Drug NameChemical ClassPharm ClassMOA
Acetaminophen p-amino phenol antipyretic analgetic may inhibit COX-3
Salicylamide salicylate NSAID (NSAIA) rev. inhib. COX-1 COX-2
Sodium salicylate salicylate NSAID (NSAIA) rev. inhib. COX-1 COX-2
Magnesium salicylate salicylate NSAID (NSAIA) rev. inhib. COX-1 COX-2
Choline salicylate salicylate NSAID (NSAIA) rev. inhib. COX-1 COX-2
Salsalate salicylate NSAID (NSAIA) rev. inhib. COX-1 COX-2
Diflunisal salicylate NSAID (NSAIA) rev. inhib. COX-1 COX-2
Ibuprofen arylpropionic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Fenoprofen arylpropionic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Ketoprofen arylpropionic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Flurbiprofen arylpropionic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Naproxen arylpropionic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Indomethacin arylacetic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Sulindac arylacetic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Tolmetin arylacetic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Diclofenac arylacetic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Ketorolac arylacetic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Nabumetone arylacetic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Etodolac arylacetic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Oxaprozin arylacetic acid NSAID (NSAIA) rev. inhib COX-1 COX-2
Mefenamic acid antranilic acid non-narcotic rev. inhib COX-1 COX-2
Meclofenamate antranilic acid non-narcotic rev. inhib COX-1 COX-2
Rofecoxib triaryl sulfonamide COX-2 sel. NSAID sel. rev. inhibits COX-2
Celecoxib triaryl sulfonamide COX-2 sel. NSAID sel. rev. inhibits COX-2
Piroxicam oxicam NSAID (NSAIA) rev. inhib COX-1 COX-2
Meloxicam oxicam NSAID (NSAIA) rev. inhib COX-1 COX-2
Misoprostol prostaglandin anti-ulcer agent PG agonist
Carboprost prostaglandin uterine active agent PG agonist
Dinoprostone prostaglandin uterine active agent PG agonist
Alprostadil prostaglandin anti-impotence drug PG agonist
Epoprostenol prostaglandin antihypertensive PG agonist
Latanoprost prostaglandin anti-glaucoma agent PG agonist
Travoprost prostaglandin anti-glaucoma agent PG agonist
Bimatoprost prostaglandin anti-glaucoma agent PG agonist
Unoprostone prostaglandin anti-glaucoma agent PG agonist
Anakinra rDNA der protein antirheumatic antagonizes IL-1RI interleukin receptors
Etanercept rDNA der protein antirheumatic binds to circulating TNF-alpha
Zafirlukast miscellaneous anti-asthmatic inhibits cysteine leukotrienes
Montelukast miscellaneous anti-asthmatic inhibits cysteine leukotrienes
Zileuton miscellaneous anti-asthmatic inhibits leukotriene biosynthesis
Aurothioglucose gold salt antirheumatic inhibits lysosomal enzymes
Auranofin gold salt antirheumatic inhibits lysosomal enzymes
Gold Sodium thiomalate gold salt antirheumatic inhibits lysosomal enzymes
Penicillamine Thiol DMARD chelating agent
Hydroxychloroquine 4-aminoquinoline DMARD dec lysosomal enzyme release
Leflunomide isoxazole DMARD rev inhib dihydroorotaate dehydrogenase
Probenecid sulfonamide uricosuric agent inhib tubular urate reabsorption
Colchicine alkaloid uricosuric agent inhib urate deposition by inhib lactic acid release
Sulfinpyrazone pyrazolidinedione uricosuric agent inhib tubular urate reabsorption
Allopurinol purine der uricosuric agent inhib uric acid biosynthesis by inhib xanthine oxidase
Cylcopropane hydrocarbon general anesthetic non-sel CNS depression
Ethtylene hydrocarbon general anesthetic non-sel CNS depression
Halothane halogenated hydrocarbon general anesthetic non-sel CNS depression
Diethyl ether ether general anesthetic non-sel CNS depression
Enflurane halogenated ether general anesthetic non-sel CNS depression
Methoxyflurane halogenated ether general anesthetic non-sel CNS depression
Isoflurane halogenated ether general anesthetic non-sel CNS depression
Desflurane halogenated ether general anesthetic non-sel CNS depression
Servoflurane halogenated ether general anesthetic non-sel CNS depression
Nitrous oxide misc general anesthetic non-sel CNS depression
Ketamine misc general anesthetic non-sel CNS depression
Etomidate misc general anesthetic non-sel CNS depression
Propofol misc general anesthetic non-sel CNS depression
Thiopental barbiturate general anesthetic non-sel CNS depression
Methohexital barbiturate general anesthetic non-sel CNS depression
Thiamylal barbiturate general anesthetic non-sel CNS depression
Created by: tnhardin