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anitcoag
drugs test 3
| Question | Answer |
|---|---|
| anticoagulants common meds | heprin, LWMH, Coumadin |
| Heprin uses// action | MI, CVA, PE, DVT/ only prevents a clot not break up one // inhibits antithrombin lll which blocks thrombin |
| Heprin administration | IV or subq |
| Heprin s/e | bleeding, heprin induced thrombocytonpenia cbc erry day |
| Heprin monitoring | PTT 1.5 2 times control 60 70 seconds |
| Herprin counterindications | hemragic stroke |
| Heprin antidote | protamine sulfate IV |
| LMWH endings | aparin |
| common LMWH | enoxaparin "lovenox" dalteaprin "fragmin" |
| LMWH uses // interactions | DVT, primarily PE// longer half life dont give with other anticoagulents |
| LMWH administration | sq weight based only in abd // usually qd or bid// give with bubble // rotate injection sites// |
| LMWH S/E | bleed// HIT |
| LMWH monitoring | platlet count |
| direct thrombin inhibitors parenternal anticoagulants ll | iv argatroban, Bivalirubin, Lepirudin sq Desirudin |
| warfarin (coumadin) uses | oral anticoagulant // long term anticoagulanet therapy PE DVT prophalyaxis in afib |
| warfarin administration | start with heprin until coumadin reaches therapudic level |
| warfarin monitioring | PT/INR daily at first then two weeks INR of 2-3 // mechanical heart valve 2.5-3.5 |
| warfarin counterindications | bleeding disorders, PUD "peptic ulcer disease", pregnancy |
| warfarin drug and food interacions | dark leavy dark berry dark beans |
| warfarin antidote | vitamen K |
| antiplatlets uses | CAD "coronary artery disease", TIA, MI, PAD "perifieral artery disease" |
| antiplatlets oral | asprin// clopridogrel (plavix)// Ticlopidine (Ticlid)//, dipyridamole (persantine) |
| antiplatlets iv | abciximab (Reopro),// eptifibatide (integrilin),// tirofiban (aggrastat) |
| antiplatlets iv inhibit what | g2b 3a inhibitors |
| antiplatlet administration oral and IV | oral once daily IV bolus and drip for pre determined amount of time |
| antiplatlet counterindications | same as heprin and LMWH |
| antiplatlet | donquai, feverfew, garlic, ginger, ginko, and bilberry |
| thrombolytics uses | acute ishemic stroke// restore patency of central line// ST elevated MI |
| thrombolytics drugs | tenecteplase (tknase)// Alteplace (t-pa)//streptokinase |
| tenecteplase (tknase) use | MI |
| alteplace (t-pa) | stroke |
| streptokinase | central line clear |
| thrombolytics admision | IV bolus alone or with drip// must be on cardiac monitor// alert for hypotension// two 18 guauge iv becasue dont want to stick after administration |
| thrombolytics adverse effects | bleeding, hypotension, cardiac dsyrthmia, vascular collapse death |
| xaralto | used on hip and knee pt// also don't need as much lab monitoring |