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BSC2085 Exam 3
| Term | Definition |
|---|---|
| Bone (or Osseous Tissue) is what tissue type? Made up of? | Connective. Cells and Matrix. |
| The bone is covered with an external sheath called.. which has.. | Periosteum...tough outer fibrous layer of collagen and inner layer of osteogenic |
| The internal surface of a bone is lined with.. which is.. | Endosteum... a thin layer of reticular connective tissue |
| The four types of cells found in osseous tissue are.. | osteogenic cells, osteoblasts, osteocytes, and osteoclasts |
| Osteogenic cells are.. that undergo.. and differentiate into.. | stem cells... mitosis... osteoblasts |
| Osteoblasts are what kind of cell? | bone-forming cells |
| Osteocytes are.. | mature osteoblasts that have become stuck in their own matrix |
| Osteoclasts are what kind of cell? and are similar to what cell? | bone-dissolving cells. blood cells. |
| Each stem contributes a.. so the mature osteoclasts is.. | nucleus... large and multinucleated |
| The side of the cell facing the bone surface has a ruffled border that increases.. and thus enhances.. | cell surface area, efficiency of bone resorption |
| The matrix of osseous tissue consists of.. | 1/3 organic matter and 2/3 inorganic matter |
| The organic matter is synthesized by osteoblasts and includes.. | collagen, glycosaminoglycan, proteoglycans, and glycoproteins |
| The inorganic matter consists mainly of.. which is.. | hydroxyapatite.. crystalize calcium phosphate salt |
| There are two kinds of bone marrow.. (color) | red and yellow |
| Red bone marrow is.. | Hemopoietic (blood producing) |
| Yellow bone marrow consists mainly of.. and is not.. | adipose tissue... Hemopoietic (blood producing) |
| The red marrow is limited to.. | skull, vertebrae, ribs, sternum, partially pelvic girdle, and proximal heads of humerus and femur |
| The formation of the bone is called...or.. | ossification..osteogenesis |
| Bone develops by two methods: | intramembranous and endochon |
| Intramembranous Ossification produces what parts of the body? | flat bones of the skull and most of the clavicle |
| Endochondral Ossification produces what parts of the body? and develops from what? | everything else (not the flat bones of the skull and the clavicle). preexisting model composed of hyaline cartilage |
| Resorption is.. | the process of dissolving bone and returning its minerals to the bloodstream |
| Bone resorption is carried out by the.. | osteoclasts |
| Mineralization is the.. | crystallization process in which ions are taken from blood plasma and deposited into the skeleton |
| Mineralization is carried out by the.. | osteoblasts |
| Hypocalcemia (Def, cause, leads to+Def) | Calcium deficiency. EXCESSIVE EXCITABILITY OF THE NERVOUS SYSTEM. Muscle tremors, spasms, or TETANY. Tetany: inability of a muscle to relax |
| Hypercalcemia (Def and causes) | NERVOUS SYSTEM DEPRESSION, muscle weakness, sluggish reflex, and cardiac arrest |
| Calcium homeostasis is regulated by three hormones: | calcitriol, calcitonin, and parathyroid hormone |
| Calcitriol and parathyroid both _____ blood calcium concentration | Increase |
| Calcitonin _____ blood calcium concentration | Decreases |
| If a hormone INCREASES OSTEOBLAST ACTIVITY, then blood calcium levels will ____. Why? | decrease. More cells = More used up calcium used for bone |
| Decreasing osteoblast activity would cause blood calcium levels to _____. Why? | increase. Less cells = Less used up calcium for bones |
| How do Osteoclasts increase or decrease calcium? | They decrease calcium from the skeletal bone and release them into the bloodstream. So.. + Osteoclasts = + Calcium in Bloodstream - Osteoclasts = - Calcium in Bloodstream |
| Abnormal calcification of tissues is called what ossification? | ectopic ossification |
| A calcified mass in an otherwise soft organ is called a | calculus |
| Osteoporosis literally means... | "porous bones" |
| Who are at most risk of Osteoporosis? Why? | Postmenopausal white women. Lack of estrogen secretion (which controls osteoclast activity) |
| Any point where two bones meet is called.. or.. | Joint or Articulation |
| The study of join structure, function, and dysfunction is called.. | Anthrology |
| The four kinds of joints are.. | Bony, Fibrous, Cartilaginous, Synovial |
| In a FIBROUS JOINT adjacent bones are bound by what fibers? | Collagen fibers |
| There are three kinds of fibrous joints: | sutures, gomphoses, syndesmoses |
| Sutures bind the bones of the ____ together | Skull |
| The attachment of a tooth to it's socket is.. | Gomophosis |
| In a syndesmosis, two bones are bound together by.. | longer collagenous fibers |
| The most familiar joint type is.. which is covered by.. which are separated by.. | synovial joint... articular cartilage... joint cavity (a narrow space) |
| Within the joint cavity (narrow space) is a slippery lubricant called.. | synovial fluid |
| A connective tissue __(__) __ encloses the cavity and retains the fluid. It has an outer __ __ and inner, cellular ___ ___ | A joint (articular) capsule. Fibrous capsule. Synovial Membrane |
| The synovial fluid nourishes.. removes.. and lubricates | articular cartilage... waste... joint for friction-free movement |
| A bursa is | a fibrous sac filled with synovial fluid |
| The plasma membrane of a muscle fiber is called the.. and its cytoplasm is called.. | sacrolemma..sacroplasm |
| Within the sacroplasm are.. (3) | myofibrils, glycogen, myoglobin |
| The smooth endoplasmic reticulum of a muscle fiber is called the.. and it is the reservoir of.. | sacroplasmic reticumlum... calcium ions |
| Dilated end-sacs | Terminal cisternae |
| The sacrolemma has tubular infoldings called | transverse (T) tubules |
| A T tubule and the two terminal cisternae associated with it are called a.. | triad |
| Each myofibril is a bundle of protein microfilaments called.. | myofilaments |
| There are three kinds of myofilaments: | Thick, thin, and elastic |
| Thick filaments are made of several hundred molecule of a protein called | myosin |
| Thin filaments are composed mainly of two intertwined strands of protein called what actin? | Fibrous (F) actin |
| Each fibrous (F) actin is made of monomers of what actin?.. | globular (G) actin |
| A thin filament also has 40-60 molecules of another protein called.. | tropomyosin |
| Tropomyosin blocks the active sites of.. | G actin in a relaxed muscle |
| Each tropomyosin molecule has a small calcium-binding protein called | troponin |
| Elastic filaments are made of a huge springy protein called | titin (connectin) |
| Myosin and actin are called what kind of protein? | contractile proteins |
| Tropomyosin and troponin are called what kind of protein? | regulatory proteins |
| Each segment of a myofibril from one ____ to the next is called ____, which is a... | Z disc, sacromere... functional contractile unit of muscle fiber |
| One nerve fiber and all the muscle fibers innervated by it are called a.. | motor unit |
| The neutrotransmitter responsible for stimulating the muscle fiber? | Acetylcholine |
| Acetylcholine is released from.. | the synaptic knob |
| When Acetylcholine is done stimulating a muscle fiber, it is broken down by the enzyme.. | Acetylcholinesterase |
| In a _______ cell, there are more anions on the inside of the plasma membrane than outside. Thus, the plasma is electrically.. and referred to as the.. | unstimulated (resting). Polarized... Resting Membrane Potential (RMP) |
| Sodium Ions = Where's the Concentration? Charge? Called? | Outside. Positive. Depolarization. |
| Pottassium Ion = Where's the Conentration? Charge? Called? | Inside. Negative. Repolarization. |
| The calcium ion gate are regulated by.. | voltage-regulated |
| The Acetylcholine receptor ion gates are regulated by.. | ligand-regulated (neurotransmitters/chemical messages) |
| Muscle contraction or tension without a change in length is.. | isometric contraction |
| Muscle contraction with a change in length but no change in tension is.. | isotonic contraction |
| Muscles decrease in length but maintain tension is.. | isotonic concentric contractions |
| Muscle lengthens as it maintains tension is.. | isotonic eccentric contraction |
| A weight lifter uses ___ when lifting and ___ when lowering | concentric contractions, eccentric contraction |
| Two pathways for ATP synthesis | Aerobic respiration and Anaerobic fermentation |
| Aerobic respiration requires.. produces.. fatigue or no fatigue? | oxygen supply.. CO2+Water. no muscle fatigue. (primary method) |
| Anaerobic fermentation produces.. which is.. | produces lactic acid.. major contributor to muscle fatigueAnaerobic fermentation |
| Short, intense exercise (6 seconds of sprinting) uses what system for most of the ATP? | phosphagen system |
| Two physiological classes of muscle fibers | Slow oxidative (slow-twitch, red, or type I) and fast gylcolytic (fast-twitched, white, type II) |
| Slow oxidative fibers are adapted for.. | aerobic respiration |
| Fast gylcolytic fibers are adapted for.. | anaerobic fermentation |
| Muscular strength depends on factors including.. | muscle size, fascicle arrangement, and size of active motor units |
| Myocytes | Skeletal muscle cells, cardiac muscle cells, or smooth muscle cells |
| Skeletal muscle cells are also called muscle FIBERS because they are.. | long and thread-like |
| Cardiac muscle cells are also called.. | Cardiocytes |
| Each Cardiocytes is joined to other Cardiocytes through.. | intercalated discs |
| These intercalated discs contain __ and __ | electrical gap junctions (stimulation) and mechanical junctions (resistance from tear) |
| Cardiac muscle is highly resistant to fatigue because it uses.. | aerobic respiration |
| Muscle contraction in skeletal, cardiac, and smooth muscle is triggered by.. | calcium ions |
| In smooth muscle, calcium icons come mainly from.. | the extracellular fluid in the sacrolemma |
| Two functional categories of smooth muscle | Multiunit and single-unit |
| Single-unit is more ___ than multiunit. Definition? | widespread. Large # of cells contract as a unit, almost like a single cell. |
| Smooth muscles are ___ in shape | fusiform (thick in middle, tapered at ends) |
| Smooth muscles produce visible or no visible striations? | No visible striations |
| No control over smooth muscle makes them.. | Involuntary |