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MT Blood Bank
Study Questions for MT Blood Bank
| Question | Answer |
|---|---|
| The interval between blood donations | 8 weeks |
| The oral temperature of a donor must not exceed | 37.5 |
| Minimum acceptable Hgb of fingerstick for male donor | 12.5 |
| Lowest acceptable Hct by earlobe puncture fro female blood donor | 38% |
| Prospective donors who have had malaria should be: | deferred for 3 years after cessation of treatment |
| Donors who have been immunized with oral polio, measles or mumps vaccine and are symptom free are acceptable to donate after a period of | 2 weeks |
| Which biochemical change does not occur in stored blood | pasma K decreases |
| What is the acceptable temp range for a blood bank refrigerator | 1-6C |
| If blood is to be transported, the blood temp must be kept between | 1-10C |
| Which blood group system was discovered first | ABO |
| What is an amorph | a gene with no observable effect |
| Plasma form donors of what blood group can be transfused to an recipient | AB |
| Which antibody is associated with Delayed Transfusion Reaction | Anti-JKa |
| Naturally occurring antibodies are found regularly in which blood group system | ABO |
| Characteristics of naturally occuring antibodies | React best in saline react best at room temp or 4C do not usually cross the placenta |
| Immune antibodies may be produced by | intermuscular injection of blood pregnancy repeated blood tranfusions |
| What is the dosage effect | Stronger reactions with homozygous cells than with heterozygous cells |
| Anti-A1 is a seed extract from | Dolichos biflorus |
| The frequency of Group A individuals in the US is | 41% |
| Group B individuals | have anti-A in their sera |
| Which blood group will not be agglutinated by Anti-A,B typing serum | 0 |
| Which blood group reacts most strongly with anti_H | 0 |
| What reagent is made from the seeds of the Dolichos Biflorus | anti-A1 |
| Who proposed a numerical Rh Nomenclautre | Rosenfield |
| What is a true characteristic of of Du | Du is a weak variant of the Rh0(D)antigen |
| A Du of the gene interaction variety would have what genotype | DuCe/dCe |
| What cells will Anti-C not react with | rr cells |
| Anti E will react with | R2R2 Cells |
| The f antigen refers to | ce |
| The symbol for the Bombay blood group | Oh |
| What antibodies will be detected in the sera of a Bombay Genotype | A,B,H |
| Which system is composed of antigens found primarily in saliva and plasma | Lewis |
| In the Duffy blood group which genes ar codominate | Fya and Fyb |
| An acquired antibody | anti-Jka |
| The antigen I is | absent on all cord cells |
| Washed red cells tested with anti d and Rh control with a pos anti D and pos Rh control is most likely caused by | cells coated with immunoglobulin (pos DAT) |
| What percentage of the population has the anti-Lea antibody | 1% |
| What percentage of US caucasian population lacks the Kell antigen | 90% |
| Anti-K does NOT react best | in saline at room temperature |
| Anti K is also known as | anti-cellano |
| what is the frequency of Fy(a-b-) in blacks | 68% |
| What is the frequency of Fy (a-b-) in caucasians | very rare |
| There is an association between the Fy(a-b-) phenotype and resistance to | malaria |
| What percentage of males are Xga positive | 64% |
| What percentage of females are Xga Negaive | 12% |
| What color code is used for donor blood labels, Group A | yellow |
| What is the standard acceptable color for anti A grouping serum | blue |
| what is the color of dye added to commercially prepared antiB blood grouping serum | yellow |
| Anti A1B serum confirms | Group O individuals |
| What are suitable medium for suspension of red cells for BB | saline, serum, albumin |
| What is NOT suitable medium for suspension of red cells for BB | distilled water |
| What enzymes are used in BB procedures | ficin,bromelin,papain |
| What enzyme is NOT used in BB procedures | amylase |
| Enzymes prevent detection of antibodies in the? | Duffy System |
| Elution? | The technique used to remove antibody bound to sensitized red cells |
| The Donath-Landsteiner Test is associated with | PCH (parosysmal cold hemoglobinuria) |
| A cold autoagglutinin will usually have specificity for the | I antigen |
| PCH if often associated with antibodies of which system | P |
| Forward grouping is | using known serum antibodies to detect unknown antigens |
| Reverse grouping difficulties may be encountered in what instances | newborns, geriatric and chemotherapy patients |
| Someone forward groups as an AB but reverse groups as B probably is a group A2B with | anti A1 |
| The most dangerous antibodies in the blood bank are those that react at | 37C |
| The best screening test for the detection of a large fetomaternal hemorrhage is | Erythrocye rosetting test |
| The DAT using polyspecific combs sera is not of value in | differentiation of cell surface coating (complement or IgG) |
| a Poly specific anti-human serum contains at lest antibodies to | IgG and C3d |
| The DAT is most useful for? | HDN |
| In a DAT you are testing | patient cells |
| IDAT tests are used for? | detection of circulating antibody in patients serum |
| when using chemically modified Anti-D, the recommended control is? | ABO grouping |
| A false neg Antiglobulin test can be caused by? | inadequate washing |
| What is the most common reason for mixed field agglutination | transfused cells mingling with patient cells |
| the minor crossmatch | detects donor serum that react with recipient cells |
| Which antibody is considered clinically significant | Anti-Kidd |
| Which antibodies are usually considered clinically insignificant | anti-lea,anti-M,anti-P1 |
| Which antibody is inactivated or destroyed by enzyme treatment | anti-Fya |
| if a recipient is incompatible with only one donor, one should suspect | a recipient antibody to a low incidence antigen |
| which antibody is present in 1:8 XM | anti-kell |
| If a group O is xm for a group b recepient | the minor xm will be incompatible |
| platelet concentrates are often used to treat patients with | thrombocytopenia |
| cryoprecipitated AHF is not used to treat | Hemophilia B |
| Deglycerolyzed frozen rbc must be transfused within how many hrs | 24 |
| recurrent nonhemolytic febrile transfusion reactions are usually caused by | anti-HLA antibodies, platelet antibodies, white cell antibodies |
| HDN can occur when | the lacks an antigen the infant possesses |
| what antibody is most likely to be involved in HDN | anti-c |
| when sever HDN is due to an unidentified antibody | the mothers rbc's may be used for transfusion |
| which blood group has not been reported to cause HDN | P |
| In case of HDN when the mother is O and the baby is A1, red cells for an exchange should be of what type | 0 |
| in cases of ABO HDN the mother is usually what type | 0 |
| what percentage of donor blood test would be compatible of an anti-e transfusion | 2% |
| what percentage of donor blood is compatible with a patient who has anti-jka | 25% |
| to find two units of compatible blood for a patient who has anti-jka how many units will have to be crossmatched | 10 |
| A 56C water bath is commonly used for | preparing eluates, inactivating sera |
| testing media for antigen/antibody reactions include | isotonic saline, LISS, albumin, enzymes |
| Anti A1 agglutination is found | occasionally in A2 pts and group b and o pts |
| weak agglutination with anti A sera is to be expected with which blood groups | A2 and A2B |
| weak agglutination with anti-A sera can be expected with | A2 and A2B groups |
| Anti-A1B is obtained from | is obtained from group o individuals and also confirms group o individuals |
| Rh antibodies | react more strongly at 37C than at 4C are acquired from transfusion or pregnancy can cross the placenta |
| Which antibodies are naturally occuring | anti P1, anti Lea, anti-S |
| in a very acute phase of hepatitis, what would indicate an onset of a viremic state | positive HBSAg |
| what is the expiration date of RBC preserved with citrate-phosphate-destrose adenine(cpda-1) | 35 days |
| LISS | causes decrease in electropositive catiosn surrounding RBC usually consists of phospate saline and glycine enhance the rate and sensitivity of antigen antibody reactions |