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Stack #1223544

FARM- Antacids

QuestionAnswer
Non-systemic Antacids? aluminum-salts; calcium-salts; magnesium-salts; magaldrate
Systemic Cantacids? Sodium Salts
Magnesium-based antacids? Mg Hydroxide; Mg chloride; Mg carbonate; Mg oxide; Mg trisilicate
Calcium-based anatcid? Calcium Carbonate
Aluminum based antacid? Aluminum hydroxide
General antacid mechanism of action? NEUTRALIZE acids already released from parietal cells; also shown to increase LES tone
What is the acid neutralizing capacity? The standard of measuring antacid potency. The neutralizaiton of acid within a given time period
Calcium agents onset, DOA, ANC? rapid, long, very good
Aluminum agents onset, DOA, ANC? Slow, shorts, fair
Magnesium agents onset, DOA, ANC? rapid, long, good
Sodium agents onset, DOA, ANC? rapid, short, fair
Magaldrate is what? a hydroxy-magnesium/aluminum chemical union complex; rapidly converted to Mg and Al in presence of acid
Simethicone is what? a surfactant that decreases surface tension which aids in expulsion of gas. You fart more
Alginic Acid acts how? forms a viscous sodium alginate solution which floats on GI contents and coats the esophagus during reflux; considered inactive ingredient
Aluminum antacids Adverse Effects? *Constipation; hypophosphatemia (acute tx for hyperphosphatemia; renal osteodystrophy, encephalopathy
Magnesium Side effects? *Diarrhea (stool-softening activity); Hypermagnesemia
Calcium Adverse Effects? *Constipation; hypercalcemia (Milk-Alkali Syndrome--nephropahty and metabolic alkalosis); hypophosphatemia; calcium based kidney stones
Sodium Adverse Effects? Gas/Flatulence; *Hypernatremia
Antacid Combinations are theoretically supposed to...?> balance the adverse effects of constipation and diarrhea
Drug interactions with antacids? So many that the baseline rule is that you give an antacid 1-2 hours before or 2-4 hours after taking other meds
Created by: gtseiler
 

 



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