click below
click below
Normal Size Small Size show me how
Stack #1223544
FARM- Antacids
| Question | Answer |
|---|---|
| Non-systemic Antacids? | aluminum-salts; calcium-salts; magnesium-salts; magaldrate |
| Systemic Cantacids? | Sodium Salts |
| Magnesium-based antacids? | Mg Hydroxide; Mg chloride; Mg carbonate; Mg oxide; Mg trisilicate |
| Calcium-based anatcid? | Calcium Carbonate |
| Aluminum based antacid? | Aluminum hydroxide |
| General antacid mechanism of action? | NEUTRALIZE acids already released from parietal cells; also shown to increase LES tone |
| What is the acid neutralizing capacity? | The standard of measuring antacid potency. The neutralizaiton of acid within a given time period |
| Calcium agents onset, DOA, ANC? | rapid, long, very good |
| Aluminum agents onset, DOA, ANC? | Slow, shorts, fair |
| Magnesium agents onset, DOA, ANC? | rapid, long, good |
| Sodium agents onset, DOA, ANC? | rapid, short, fair |
| Magaldrate is what? | a hydroxy-magnesium/aluminum chemical union complex; rapidly converted to Mg and Al in presence of acid |
| Simethicone is what? | a surfactant that decreases surface tension which aids in expulsion of gas. You fart more |
| Alginic Acid acts how? | forms a viscous sodium alginate solution which floats on GI contents and coats the esophagus during reflux; considered inactive ingredient |
| Aluminum antacids Adverse Effects? | *Constipation; hypophosphatemia (acute tx for hyperphosphatemia; renal osteodystrophy, encephalopathy |
| Magnesium Side effects? | *Diarrhea (stool-softening activity); Hypermagnesemia |
| Calcium Adverse Effects? | *Constipation; hypercalcemia (Milk-Alkali Syndrome--nephropahty and metabolic alkalosis); hypophosphatemia; calcium based kidney stones |
| Sodium Adverse Effects? | Gas/Flatulence; *Hypernatremia |
| Antacid Combinations are theoretically supposed to...?> | balance the adverse effects of constipation and diarrhea |
| Drug interactions with antacids? | So many that the baseline rule is that you give an antacid 1-2 hours before or 2-4 hours after taking other meds |