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Insulins
NU122 Insulins
| Question | Answer |
|---|---|
| Types of Insulins | - Rapid-acting - Short-acting - Intermediate-acting - Long-acting - Very Long-acting |
| Rapid-acting Insulin | - have onset of 5 - 15 minutes - Peak action of 1 hour - duration of 2-4 hours - person should eat no more than 5 - 15 min after injection. |
| Names of Rapid-acting Insulins | - Lispro(Humalog) - Aspart(Novolog) - Glusine(Apidra) |
| Lispro(Humalog) | - Onset 10 - 15 min. - Peak 1 hour - Duration 3 hours |
| Aspart(Novolog) | - Onset 10 - 15 min. - Peak 40 - 50 min. - Duration 4 - 6 hours |
| Glusine(Apidra) | - Onset 5 - 15 min. - Peak 30 - 60 min. - Duration 2 hours |
| Indications for Rapid Acting Insulins | - Used for rapid reduction of glucose levels - to treat postprandial hyperglycemia - to prevent nocturnal hypoglycemia |
| Short-acting Insulins | - Onset 30 min - 1 hr. - Peak 2 - 3 hours - Duration 4 - 6 hours - clear solution and should be admin. 20 - 30 minutes before meal either alone or with longer-acting insulin |
| Names of Short-acting Insulins | - Regular - Humalog R - Novolin R - Iletin II Regular |
| Regular(Humalog R, Novolin R, Iletin II R) | - Onset 30 min - 1 hr. - Peak 2 - 3 hours - Duration 4 - 6 hours |
| Indications for short-acting Insulins | - Usually given 20 - 30 min before a meal - may be taken alone or in combination with longer acting insulin |
| Intermediate-acting Insulin | - Called NPH(Neutral Protamine Hegedorn) or Lente - Onset 3 - 4 hours - Peak 4 - 13 hours - Duration 16 - 20 hours - Appear white or cloudy |
| Names of Intermediate-acting Insulins | - NPH(Neutral Protamine Hagedorn) - Humulin N - Iletin II Lente - Iletin II NPH - Novolin L(Lente) - Novolin N(NPH) |
| NPH | - Onset 2 - 4 hr. - Peak 6 - 12 hrs. - Duration 16 - 20 hours. |
| Humulin N, Iletin II Lente, Iletin II NPH, Novolin L, Novolin N | - Onset 3 - 4 hours - Peak 6 - 12 hours. - Duration 16 - 20 hrs. |
| Indications for Intermediate-acting Insulin | - If NPH or Lente insulin is taken alone if is not crucial that it be taken 30 minutes before meal - Important for patient to eat some food around the time of onset and peak |
| Long-acting Insulins | - Called Ultralente - referred to as peakless insulins because they tend to have a long slow sustained action - Onset 6 - 8 hours - peak 12 - 16 hours - Duration 20 - 30 hours |
| Names of Long-acting Insulins | - Ultralente (UL) |
| Indications of Long-acting Insulins | - Used primarily to control fasting glucose levels. |
| Very long-acting Insulins | - Peakless basal insulin - glargine(Lantus) - approved for basal insulin - absorbed very slowly over 24 hrs. - give once a day - has a pH of 4 so it cannot be mixed with any other insulin. |
| Names of Very Long-acting Insulins | - Glargine(Lantus) |
| Glargine(Lantus) | - Onset 1 ht - Peak Conitnuous No Peak - Duration 24 hours |
| Indications of Very Long-acting Insulins | - Used for basal dose - Given once a day at bedtime - cannot be mixed with other insulin will cause precipitation |
| How often does the pancreas release insulin | - Every 10 - 15 minutes |
| Long Acting Basal Insulin | - Body Normally secretes insulin q 10 - 12 minutes to control hepatic glucose production. - This is unrelated to meal intake |
| Nutritional Insulin | - Body Normally secretes rapid acting insulin in response to meal time carbohydrate intake |
| Correction Insulin | - Insulin given to treat acute elevations in blood glucose. - This is also known as sliding scale insulin |
| Rainbow Coverage insulin Therapy | - Regular or humalog insulin is given on a sliding scale depending on the blood glucose level. - Higher the Blood Glucose level the more units of insulin given. |
| What are the sites for insulin injection | - Abdomen - Arm - Thigh |
| What insulin can be given by IV | - Regular only |
| What Insulin cannot be mixed with any other in the same syringe | - Lantus - levemir |
| What can be mixed with NPH but must be injected immediately | - Apidra - Regular - Humalog - Novolog |
| Mixing Insulins | - Air into Cloudy (Long Acting) - Air into Clear (Short Acting) - Draw Up Clear (Short Acting) - Draw Up Cloudy (Long Acting) |
| Insulin Safety | - Write out the word "Units" - All insulin admin must be double checked by a second nurse - Insulin orders must be time specific |