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Hematology Test 3
Hematology Test 3 Ch 6 including end of chapter questions
| Question | Answer |
|---|---|
| What is the approximate size of an RBC? | 6-8 um |
| What color do RBCs stain with a Wright's stain? | reddish orange |
| What are two questions you must ask yourself when doing an RBC morphology? | is it seen in every field, and is it pathologic or artifically induced |
| Describe normocytic cells. | normal RBCs, with an MCV of 70=100fl |
| Describe macrocytic cells | larger than normal RBCs with an MCV of >100fl |
| Describe microcytic cells | smaller than normal RBCs with an MCV of <70fl |
| What is a mixture of small and large RBCs called? When do you see it? | a dimorphic population, seen in treatment of anemias and blood transfusions |
| What is anisocytosis? | general terminology to describe RBC size |
| What is RDW? | measures variation in red cell distribution |
| What causes macrocytosis? | defect in DNA synthesis, accelerated erythropoiesis, incresed membrane cholesterol |
| What causes microcytosis? | defective hemoglobin synthesis, insufficient iron, defective globin synthesis, malabsorption syndrome |
| What is poikilocytosis? | general term used to describe variations in shape |
| What causes poikilocytosis? | chemical of physical alterations |
| What is an acanthocyte? | aka thorn or spur cell, a few irregular shaped spines protruding from an RBC |
| What is a blister cell? | RBC with a vacuole that resembles a blister on the skin, if ruptured it becomes a cell fragment (shistocyte) |
| What is an echinocyte? | burr cell, many evenly distributed spiny projections |
| What are crenated RBCs? | scallped projections evenly distributed, usually due to osmotic imbalance |
| What are eliptocytes? | ovalocytes, elongated, rod or cigar shaped |
| What are shistocytes? | helmet cells, cell fragments, usually caused after a blister cell ruptures |
| What are sickle cells? | RBC is elongated and pointed on at least one end |
| What is a sperocyte? | RBC is round with no central pallor, usually smaller than normal RBC, stains slightly differently than normal RBC |
| What are stomatocytes? | slit-like opening that resembles a mouth |
| What are codocytes? | target cells |
| What are dacryocytes? | tear drop |
| Describe a hypochromic cell | central pallor exceedes 1/3 diameter of the cell, MCHC <30% |
| Describe polychromasia | blue gray color when Wright's stained, usually retics |
| What is basophillic stippling? | Robin's egg, course granulation from RNA aggregates |
| What are cabot rings? | thread-like round oval or figure 8 loops |
| What are hemoglobin C crystals? | oblong hexagonal crystals |
| What are Heinz bodies? | inclusions only seen with supravital stain (new methelyene blue, cyrstal violet) due to denatured hemoglobin |
| What do Heinz bodies look like on a Wright's stain? | blister cells |
| What are Howell Jolly bodies? | one or two round, solid, dark-blue to purple inclusions |
| What are Pappenheimer bodies? | siderotic granules, iron aggregates, purple dots in the RBC |
| What is agglutination? | clumping of RBCs |
| What is rouleaux? | stacking of coins appearance in RBCs |
| Will sickle cells increase or decrease O2 levels in the body? | decrease |
| Granules composed of ribosomes and RNA are | basophilic stippling |
| DNA in RBC is | Howell-Jolly bodies |
| Precipitated denatured hemoglobin is | Heinz bodies |
| Aggregates of iron, mitochondria, and ribosomes are | Pappenheimer bodies |
| What is a term for RBCs resembling a stack of coins? | Rouleaux |
| What cells result from iron deficiency anemia? | microcytes |
| What cells result from abetalipoproteinemia? | acanthocytes |
| What cells result from G6PD deficiency? | Heinz bodies |
| What cell type is not related to a disease state? | echinocytes |
| What cells result from hepatic disorders? | leptocytes |
| What cells result from hemolytic disease of the fetus and newborn? | microspherocytes |
| What cells result from hemoglobinopathies? | codocytes |
| What cells result form pernicious anemia? | macrocytes, dacrocytes and Howell-Jolly bodies |
| What cells result from iron loading anemia? | Pappenheimer bodies |
| What cells result from lead poisoning? | basophilic stippling |
Created by:
robinly1