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Micro Ch. 24 ???
Microbiology Ch. 24 - Antimicrobial Drugs - Book Questions
| Question | Answer |
|---|---|
| 1. Ehrlich and Hata discovered _____ that was used to treat ______? A. Salvarsan; syphilis B. penicillin; surgical wounds C. Salvarsan; malaria D. Prontosil; malaria | C. Salvarsam; malaria ? |
| 2. The re-isolation and purification of penicillin was carried out by? A. Waksman B. Florey and Chain C. Domagk D. Fleming | B. Florey and Chain |
| 3. The concentration of an antibiotic causing harm to the host is called the A. toxic dosage level B.therapeutic dosage level C.minimal inhibitory concentration D. chemotherapeutic index | A. toxic dosage level ? |
| 4. In the soil, antibiotics are produced by some A. fungal species and viruses B. bacterial species and viruses C. Viruses and helminthic species D. Fungal and bacterial species | D. fungal and bacterial species |
| 5. Trimethoprim and sulfamethoxazole are examples of _____ that block _____ synthesis. A. sulfonamides; OABA B. penicillins; cell wall C. sulfonamides; folic acid D. macrolides; protein | C. sulfonamides; folic acid? |
| 6. Isoniazid and ethambutol are used to treat A.cholera B.Influenza C.MRSA D.tuberculosis | D. tuberculosis |
| 7. Penicillins are useful in treating A.gram-positive infections B.leprosy C.gram-negative infections D.Tuberculosis | A. gram-positive infections ? |
| 8. All the following are drugs or drug classes blocking cell wall synthesis except: A. cephalosporins B. Carbapenems C. Monobactams D. Tetracyclines | D. Tetracylines |
| 9. Vancomycin inhibits ______ synthesis. A.protein B.DNA C.bacterial cell wall D.RNA | A. protein ? |
| 10. Two cyclic polypeptide antibiots are A.vancomycin and streptomycin B.penicillin and cephalosporin C.bacitracin and polymyxins D.gentamicin and chloramphenicol | C. Bacitracin and Polymyxins |
| 11. Which on of the following is NOT and inhibitor of protein synthesis? A.clindamycin B.Macrolides C.Rifampin D.Chloramphenicol | C. Rifampin ? |
| 12. Antibiotics inhibiting Nucleic Acid Synthesis include A. Rifampin and Quinolones B. aminoglycosides and tetracyclines C.lincosamides and streptogramins D. macrolides and aminoglycodies | A. Rifampin and Quinolones |
| 13. Antiviral drugs that are base analogs inhibit A.viral entry B.genome replication C.uncoating D.naturation | C. Uncoating ? |
| 14. Antifungal drugs, such as _____, inhibit proper formation of ____. A. miconazole; a plasma membrane B. griseofulvin; DNA C. ketoconazole; a cell wall D. flucytosine; a microtubule | A. miconazole; a plasma membrane |
| 15. All of the following anitprotozoal drugs have been use to treat malaria except: A. melarsoprol B. quinine C. mefloquine D. Chloroquine | A. Melarsoprol ? |
| 21. Tetracycline has four benzene rings in the molecule. | True ? |
| 22. Sulfonamides block folic acid formation in fungi. | False - Sulfonamides block acid formation in bacterial cells. |
| 23. Gentamicin is an antibiotic that interferes with transcription. | True ? |
| 24. A side effect of chloramphenicol is a discoloration of the teeth. | False - Tetracycline causes a discoloration of the teeth |
| 25. Penicillinase also is known as an aplha-lactamase. | False ? |
| 26. Polymyxin B affects membrane permeability | True |
| 27. Folic Acid synthesis is inhibited by rifampin. | False ? |
| 28. Penicillin has no effect on viruses | True |
| 29. Artemisinin is a drug that releases free radicals. | True ? |
| 30. Neosporin contains bacitracin, polymysxin B, and tetracycline | False - Neosporing contains bacitracin, polymysxin B and neomycin |
| 31. Sulfmonides act here. | cell wall ? |
| 32. Plymyxin B affects this structure | membrane |
| 33. Rifampin blocks this process | DNA ? |
| 34. Quinolones act here | DNA |
| 35. Tetracyclines inhibit the function of this structure | mitochondria ? |
| 36. Cephalosporins target this structure | cell wall |
| 37. The macrolides act here | protein synthesis ? |
| 38. Vancomycin inhibits the assembly of this structure | cell wall |
| 39. Aminoglycosides inhibit this structure | ribosomes ? |
| 40. Penicillin acts here | cell wall |