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Biological Effects
Biological Effects & Radiosensitivity
| Question | Answer |
|---|---|
| mitosis | non-reproductive cell replication |
| epithelial | sheet-like arrangement of cells that line or cover body surfaces |
| free radicals | extermely reactive atoms containing unpaired electrons in outer shell |
| RBE | ionization effectiveness of one type of radiation as compaired to another |
| hematopoesis | formation of blood cells in the red bone marrow |
| prodromal | initial phase of radiation sickness characterized by nausea, voniting, diarrha |
| weight factor | the number used accurately calculate radiation dose to different body parts |
| meoisis | grem cell reproduction |
| differentation | the process by which cells grow to become specialized |
| genetic | effect seen in the descendants of exposed individuls |
| lymphocytes | specialized white blood cell that produce antibodies to fight disease |
| somatic | the effects of radiation on non-reproductive cells of an individual |
| gestation | period between conception and birth |
| OER | ratio comparing the radiation dose, tissue oxygenation, and tissue response |
| alopicia/epilation | skin responce to radiation in which the hair falls out |
| erythroblast | precursor cell to a red blood cell |
| erythema | redness of skin after exposure to radiation |
| desqumation | shedding of the outer layer of skin |
| mitotic death/genetic death | cell death after a few divisions |
| spermatogoonia | male germ cell |
| stem cell/precurser | a type of primitive cell that can transform into and generate other cells |
| radiolysis | the seperation of the cytoplasm molecules by an incoming photon |
| mutation | changes in genes causes by the loss of a base in the DNA |
| catatactogenesis | long term somatic effect on optic lens |
| probabilistic | mutational, non-threshold random somatic effects in which the chance, but not severity, of effects increases with dose |
| protracted | low dose of radiation continually delivered over a long time |
| latent/delayed | effects seen in an individual months or years following exposure |
| stem cell precurser | unidentified cells that become specialized for various body tissues |
| doubling dose | quantity of radiation required to double the amount of mutations that occur naturally |
| gonads | male or female reproductive organs |
| GSD | the dose of radiation given to the entire population that would cause a genetic effect |
| direct | radiation interacting w/out an intermediary on the macromolecules of a cell |
| dose responce curve | graphic illustration of the responce of tissue to radiation |
| mature | highly differentiated cells |
| non-stochastic | deterministic somatic effects that can be directly related to the dose they recieve |
| manifest | stage at which the effects of radiation are visibly seen |
| desqumation | radiation syndrome responsible for a reduction in epithelial cells |
| leukemia | cancer of the blood characterized be excessive numbers of white blood cells |
| radiolysis | interaction of radiation with water |
| cell survival curve | method of displaying the radiation sensitivity of a specific type of cell |
| latent | period is which no visible effects of radiation syndrome are seen |
| mutation | changes in genes caused by the loss of a basein the DNA chain |
| carcinogenesis | process which leads to developement of cancer |
| stocastic | randomly occuring mutational probabilistic biological effects |
| prodromal | stage of radiation sickness occuring within hours after whole body absorbed dose |
| free radicals | extremaly reactive atoms containing unpaired electrons in the outer shell |
| desqumation | the shedding of the outer layer of the skin |
| epithelial | radiosensitive tissue group tha lines and covers body tissue |
| erytherima | skin reddening |