Immuno 11 Hypersens Word Scramble
|
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Question | Answer |
Other name; cells and Ab implicated: Type 1 | Immediate hypersensitivity; mast/eosinophils, IgE, TH2 |
Other name; cells and Ab implicated: Type 2 | Antibody-mediated disease; IgG,/IgM Ab on extracellular or cell surface, activated neuts/macrophages |
Other name; cells and Ab implicated: Type 3 | Immune complex-mediated diseases; immune complexes against vascular basement membranes |
Other name; cells and Ab implicated: Type 4 | T-cell mediated diseases; delayed with CD4+ T cells w/ macrophage activation; cytolysis w/ CD8+ CTLs |
Cause and effect of late phase reaction in Type I reactions | mast cell released cytokines recruit neuts and lymphs. |
What is FcεR1? What 2 cells is it present on? | high affinity IgE Fc receptor; on mast cells and basophils |
2 substances from mast cells that cause vascular dilation | vasoactive amines (histamine), prostaglandins |
Mast cells release these substances to attract neutrophils and eos. | IL-4 and TNF |
Eosinophils activated by this | IL-5 |
2 substances from mast cells that cause smooth muscle contraction | vasoactive amines (histamine), Leukotrienes |
This IL causes increased mucus secretion | IL-13 |
Myasthenia gravis results from autobodies against what? That cause what? | ACh Receptors; inactivating the receptor |
Graves’ disease results from Auto-Ab against what? Resulting in what? | TSH receptors; activating the receptor in absence of TSH |
Pernicious Anemia; Ab to? Causes? | Intrisic factor Ab; neutralizes IF and decreases B12 absorption; anemia |
Ab to e-cadherin causes? | pemphigus vulgaris; skin bullae |
Ab to kidney and lung BM causes? | Goodpasture’s syndrome; nephritis, lung hemorrhages |
Arthrus reaction is? | cutaneous vasculitis at injection site of a previous vaccinated person with protein antigen |
What do superantigens do? | activate large numbers of T cells |
Poison ivy reaction, tuberculosis, liver injury in hepatitis virus are what type of reactions | T cell medited; type 4 |
Activation of TH1 cells causes what to be released, resulting in what? | releases INF-γ; activating macrophages |
Activation of TH17 cells causes what? | leukocyte recruitment |
Type 1 DM: T-cells attack? Genetic? | pancreatic islet cells; insulin gene/PTPN22 |
RA: T-cells attack? Genetic? | unknown Ag in joints; PTPN22 |
Multiple Sclerosis: T-cells attack? Genetic?2 Myelin proteins; CD25 | |
IBD: T-cells attack? Genetic? | unknown; NOD2 |
Toxic Shock Syndrome: T-cells attack? | superantigens cause massive t-cell response |
Created by:
csheck
Popular Science sets