Drugs for Biochem 2 Word Scramble
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Question | Answer |
Inhibits complex III (Cytochrome c reductase) of the ETC | Antimycin A |
Inhibits ATP translocase | Aphidicolin |
Prevents ATP production by phosphoglycerate kinase | Arsenate |
Irreversible inhibitor of COX-1 | Aspirin |
Inhibits CPSII, CTP synthetase and PRPP amidotransferase | Azaserine |
Inhibits carbamoyl phosphate synthetase II | Azaserine |
Chain terminators to inhibit viral DNA repliation | AZT and didanosine |
Inhibits Complex IV (Cytochrome oxidase) of the ETC | Cyanide, CO, Azide (N3) |
Inhibits Na+/K+-ATPase | Digoxin |
Covalently modifies eEF2, inactivates it and inhibits translation | Diptheria toxin |
Inhibits Type II topoisomerase in humans | Etoposide |
Inhibits enolase | Flourine |
Suicide inhibitor of thymidylate synthase | Fluorouracil |
Inhibits thymidylate synthase | Fluorouracil |
An anticancer drug that is a suicide inhibitor of thymidylate synthetase | Fluorouracil |
This anticancer drug inactivates thymidylate synthetase and therefore inhibits DNA synthesis. | Fluorouracil |
Effective in the treatment of DVT because it acts to inhibit the activity of thrombin | Heparin |
Used in the treatment of tuberculosis, this reacts with pyridoxal leading to a B6 deficiency | Isoniazid |
Inhibits de novo synthesis of purines, thereby inhibitin DNA synthesis. | Mercaptopurine |
Inhibits aspartate transcarbamoylase (the pyrimidine biosynthetic enzyme) and prevents DNA replication | N-phosphonacetyl-L-aspartate) PALA |
Irreversible inhibitor of transpeptidase involved in cell wall synthesis | Penicillin |
These three enzymes inhibit DNA gyrase and prevent the growth of E. coli | Quinolones, nalidixic acid and ciprofloxacin |
Hydrolyzes 28S RNA and inactivates ribosomes | Ricin |
Ligand for estrogen receptor | Tamoxifen |
Vitamin K analog that inhibits the regeneration of Vitamin K | Warfarin (Coumadin) |
Antibacterial agents which competitively inhibit digydropteroate synthase | Sulfonamides |
Inhibits dihydrofolate recuctase (DHFR) | Trimethoprim |
Inhibits ATP Synthase | Oligomyacin |
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