WVSOM - FA synthesis Word Scramble
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Question | Answer |
When does FA synthesis occur? | When there are more calories ingested than are needed |
Beginning Product of FA synthesis | Citrate |
Citrate converted into what two products in preparation for FA synthesis | Oxaloacetate and Acetyl CoA |
Acetyl CoA goes to what | Malonyl CoA |
Malonyl CoA | 3 Carbon compound needed for the immediate sgtarting material for FA synthesis |
What cofactor is needed in all carboxylases? | biotin |
Fate of oxaloacetate from citrate lyase reaction | Oxaloacetate -> Malate -> Pyruvate |
Location of FA synthesis | Hepatic cytosol |
When is FA synthesis active | Fed state assuming excess calories present |
FA synthesis Starting material | NADPH Malonyl CoA Acetyl CoA |
FA Synthesis Products | NADP+ Palmitate |
Process of FA synthesis | Reduction of carbons/oxidation of NADPH (reverse B oxidation) |
Where do we get NADPH? | Pentose Phosphate Pathway |
Fatty Acid Synthase | large complex of enzymes that binds growing acyl chain and malony CoA in first round. |
Why is malonyl CoA used rather than acetyl coa? | allows regulation |
Fate of new synthesized FA | activated to fatty acyl CoA for TG synthesis and incorporated into VLDL |
Created by:
tjamrose
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