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week 1 bingo definitions

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Question
Answer
the lowest concentration of drug reached in the body after it falls from its peak level, usually measured in a blood sample for therapeutic drug monitoring   Trough level  
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reduced response to a drug after prolonged use   tolerance  
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the ratio between the toxic and therapeutic concentrations of a drug   theraputic index  
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the physiologic state in which the amount of drug removed via elimination is equal to the amount of drug absorbed with each dose   steady state  
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an inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body   prodrug  
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the rate of drug distribution among various body compartments after a drug has entered the body. It includes the phases of absorption, distribution, metabolism, and excretion of drugs   pharmacokinetics  
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the study of drugs that are obtained from natural plant and animal sources   pharmacognosy  
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maximum concentration of a drug in the body after administration, usually measured in a blood sample for therapeutic drug monitoring   peak level  
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an abnormal and unexpected response to a medication, other than an allergic reaction, that is peculiar to an individual patient   idiosyncratic reaction  
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in pharmacokinetics, the time required for half of an administered dose of drug to be eliminated by the body, or the time it takes for the blood level of a drug to be reduced by 50%   half-life  
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the name given to a drug by the US adopted names council. Also called the nonproprietary name. The generic name is such shorter and simpler than the chemical name and is not protected by trademark.   generic name  
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the initial metabolism in the liver of a drug absorbed from the gastrointestinal tract before the drug reaches systemic circulation through the bloodstream   first-pass effect  
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the general name for a large class of enzymes that play a significant role in drug metabolism   cytochrome p450  
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any condition, especially one related to a disease state or other patient characteristic, including current or recent drug therapy, the renders a particular form of treatment improper or undesirable   contraindiction  
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a drug that binds to and inhibits the activity of one or more receptors in the body. Antagonists are also called inhibitors   antagonist  
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an immunologic hypersensitivity reaction resulting from the unusual sensitivity of a patient to a particular medication; a type of adverse drug even   allergic reaction  
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drug that binds to and stimulates the activity of one or more receptors in the body   agonist  
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a general term for any undesirable effects that are a direct response to one or more drugs   adverse effects  
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the use of many different drugs concurrently in treating a patient, who often has serveral health problems   polypharmacy  
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an act that protects health insurance coverage for workers and their families when they change jobs. It also protects patient information. If confidentiality of a patient is breached, severe fines may be imposed.   HIPPA ACT  
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a scientific project of the U.S Department of Energy and National Institutes of Health to describe in detail the entire genome of a human being   human Genome Project  
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drug interactions in which the effect of a combination of two or more drugs with similar actions is equivalent to the sum of the individual effects of the same drugs given alone.   additive effects  
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the commercial name given to a drug product by its manufacturer; also called the proprietary name   trade name  
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another name for prescription drugs   legend drug  
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