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Pharm Bingo Week 1
week 1 bingo definitions
| Question | Answer |
|---|---|
| the lowest concentration of drug reached in the body after it falls from its peak level, usually measured in a blood sample for therapeutic drug monitoring | Trough level |
| reduced response to a drug after prolonged use | tolerance |
| the ratio between the toxic and therapeutic concentrations of a drug | theraputic index |
| the physiologic state in which the amount of drug removed via elimination is equal to the amount of drug absorbed with each dose | steady state |
| an inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body | prodrug |
| the rate of drug distribution among various body compartments after a drug has entered the body. It includes the phases of absorption, distribution, metabolism, and excretion of drugs | pharmacokinetics |
| the study of drugs that are obtained from natural plant and animal sources | pharmacognosy |
| maximum concentration of a drug in the body after administration, usually measured in a blood sample for therapeutic drug monitoring | peak level |
| an abnormal and unexpected response to a medication, other than an allergic reaction, that is peculiar to an individual patient | idiosyncratic reaction |
| in pharmacokinetics, the time required for half of an administered dose of drug to be eliminated by the body, or the time it takes for the blood level of a drug to be reduced by 50% | half-life |
| the name given to a drug by the US adopted names council. Also called the nonproprietary name. The generic name is such shorter and simpler than the chemical name and is not protected by trademark. | generic name |
| the initial metabolism in the liver of a drug absorbed from the gastrointestinal tract before the drug reaches systemic circulation through the bloodstream | first-pass effect |
| the general name for a large class of enzymes that play a significant role in drug metabolism | cytochrome p450 |
| any condition, especially one related to a disease state or other patient characteristic, including current or recent drug therapy, the renders a particular form of treatment improper or undesirable | contraindiction |
| a drug that binds to and inhibits the activity of one or more receptors in the body. Antagonists are also called inhibitors | antagonist |
| an immunologic hypersensitivity reaction resulting from the unusual sensitivity of a patient to a particular medication; a type of adverse drug even | allergic reaction |
| drug that binds to and stimulates the activity of one or more receptors in the body | agonist |
| a general term for any undesirable effects that are a direct response to one or more drugs | adverse effects |
| the use of many different drugs concurrently in treating a patient, who often has serveral health problems | polypharmacy |
| an act that protects health insurance coverage for workers and their families when they change jobs. It also protects patient information. If confidentiality of a patient is breached, severe fines may be imposed. | HIPPA ACT |
| a scientific project of the U.S Department of Energy and National Institutes of Health to describe in detail the entire genome of a human being | human Genome Project |
| drug interactions in which the effect of a combination of two or more drugs with similar actions is equivalent to the sum of the individual effects of the same drugs given alone. | additive effects |
| the commercial name given to a drug product by its manufacturer; also called the proprietary name | trade name |
| another name for prescription drugs | legend drug |
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