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Anatomy and Physiology

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Answer
Chemical bonds   sharing of electrons between atoms  
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Molecule   two or more atoms held together by chemical bonds (sharing of electrons)  
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Chemical Reaction   chemical bonds are formed or broken apart  
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Chemical bonds contain what?   Potential Energy  
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Single Covalent Bond   Sharing one pair of electrons  
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Double Covalent Bond   Sharing two pairs of electrons  
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Rank Hydrogen, Covalent and Ionic by strength (strong, weak, very weak)   Covalent - Strong. Ionic - Weak. Hydrogen - Very Weak.  
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Two types of Covalent Bonds & properties   polar - unequal sharing of electrons & different types of atoms bonding (h20) & non polar - very equal sharing of electrons & atoms of the same type bonding (h2,02)  
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Covalent Bond   Atoms share electrons  
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Ionic Bonds   electrical attraction between ions. One atom, the electron donor looses one or more electrons and becomes a cation w + charge, while another atom, the electron acceptor gains those same electrons and becomes the electron acceptor, anion, - charge  
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Cations   positively charged ions  
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Anions   negatively charged ions  
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Hydrogen Bonds   Weak electrical attractions. Takes place between the ends of molecules and H. (ex. holds water molec. together in solution).  
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Name 3 main Properties of Water   1. High heat capacity. 2. "Universal Solvent" 3. Molecules are defined by their ability to interact with h20 (hydrophobic & hydrophilic)  
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Hydrophobic   molecules with non-polar bonds (afraid of h20)  
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Hydrophylic   molecules with polar bonds, ions (love of h20)  
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Electrolytes   Soluble inorganic olecules whose ions can conduct electrical current in solution. (anything ionic that can dissasociate in h20 (i.e. NACL -> CL-, NA+). Molecules that are electrolytes have ionic bonds that ionize (dissasociate) in h20  
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Salt   an electrolyte whose cation is not hydrogen and whose anion is not hydroxide (isn't acid or base)  
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Acids   Release hydrogen ions into solution (contains more hydrogen ions than hydroxide ions)  
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Bases   Remove hydrogen ions from solution (has more hydroxide ions than hydrogen ions)  
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PH   a measure of the concentration of hydrogen ions in solution  
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Log   Exponent  
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Normal PH range of Blood   7.35-7.45  
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Acidosis   Abnormally low blood P,H ( less than 7.35), more common than alkalosis  
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Alkalosis   Abnormally High blood PH (greate than 7.45)  
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Atkins diet causes   cidosis (ketoacidosis)  
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Inorganic Compound   Generally do not include both C &H. Examples include H20, Co2, 02, salts, inorganic acids and bases  
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The human body is composed mostly of what kind of compound? (org or inorg?)   Inorganic, mostly due to h20 making up the most of the body weight  
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Organic Compounds   always have H& C (generally include C,H, sometimes O). may have N,P,S,Fe and other trace elements  
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What is the most simple organic compound?   CH4, methane (Carbon always wants to form 4 bonds)  
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Four major classes of Organic Compounds   Carbohydrates, lipids, proteins & amino acids, nucleic acids &nucleotides  
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Polymer   A large molecule consisting of a long chain of subunits (  
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Which organic compound is not a polymer?   Lipids (why?)  
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What is the molecular composition of the human body? (h20,proteins,lipids,carbs)   h20- 66%, protein-20%, lipids- 10%, carbohydrates-3%  
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Carbohydrates   Prefix glyco, C,H,O in ratio of approximately 1:2:1 (ex. C6 H12 O6)  
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Three classes of Carbohydrates   Monosaccharides, Disaccharides, Polysaccharides  
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Monosaccharides   Type of Carbohydrate, simple sugars. ex. glucose, fructose, galactose  
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Disaccharides   Tyep of Carb, 2 monosaccharides combined. i.e. sucrose(fromed from glucose & fructose), lactose (formed from glucose & galactose)  
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Poysaccharides   type of Carb, chains of simple sugars, starch, glycogen, cellulose  
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Lipids   C,H,O present, but much less O than either, C to H ratio 1:2. example is lauric acid (C12, H24, O2), fats, oils, waxes.  
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types of Lipids   Fatty Acids, Triglicerides  
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Fatty Acid   Type of Lipid, has carboxyl group, long chain of carbon & hydrogen atoms attached. i.e. saturated, unsaturated, omega-3  
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Triglycerides   Lipid -> Glycerides -> Triglicerides. AKA Neutral fats, formed by attachment of 3 fatty acids and glyerol molecule (via dehydration synthesis) i.e. fats, oils  
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Five types of Lipids   Fatty Acids, Glycerides, Eicosanoids, Steroids, Phospholipids & Glycolipids  
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Prostaglandins, Leukotrienes   (type of Eicosanoid), short chain fatty acid in which five of the carbon atoms are joined in a ring, direct local cellular activities  
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Steroids (3ex)   Type of Lipid, ex. cholesterol, estrogen, corticosteroids(derivative of cholesterol), all have complex four ring structure, steroids differ in the side chains attached to the carbon rings  
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Phospholipids & Glycolipids   types of Lipids, help form clel membrane structure, see p 47  
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proteins   = polypeptide, linear sequences of amino acids held together by peptide bonds (most abundant organic components of the human body, all contain C,H,O,N and smaller quantities of Sulfer may also be present  
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Protein functions (7)   (p49)  
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Amino Acids (consist of 5 components)   proteins consist of long chains of organic molecules called amino acids. Components: 1. central carbon atom. 2. Hydrogen atom. 3. Amino group (-NH2) 4. Carboxylic Acid group (-COOH). 5. a variable R (radical) group or side chain  
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Buffer   Removes or replaces hydrogen ions in solution. Buffers maintain the PH within normal limits.  
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Glycoprotein   glyco = carb, large protein molecules with carbs attached. Ex. Antibodies, Hormones and Mucus  
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Proteoglycans   (carb-protein combination) large polysaccharides linked by peptide chains. Important thickening agent for tissue fluids.  
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Types of Protein Structure   primary, secondary, tertiary, quaternary  
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Primary structure   Type of protein structure, an amino acid sequence  
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Secondary, tertiary & quaternary protein bonds are primarily held together by?   hydrogen bonds. Hydrogen bonds are weak and can be denatured by disrupting H bonds with heat or PH changes  
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What will happen to proteins pushed outside of their normal PH and temp ranges?   They will change shape and cease to function  
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metabolism   the sum of all chemical reactions in the body  
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catabolism   Under Metabolism, breaks down complex molecules and releases energy (ex. cellular respiration which breaks down carbs)  
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anabolism   (Under metabolism) - synthesis of new molecules using energy (ex. to help remember - anabolic steroids)  
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metabolic turnover   continuous removal and replacement of all organic molecules except DNA  
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Enzymes   - Proteins<br /> - Catalysts <br /> - Reduce the energy of activation without being permanently changed or used up. - Promote chemical reactions at temperatures and PH levels compatible with life  
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T or F. Enzymes are needed to catalyze all chemical reactions that occur in living cells   T  
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