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Gram positive, Acid fast bacteria, Obligate Aerobic Intracellular

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Gram +, Acid fast bacteria   Mycobacterium tuberculosis, Mycobaterium bovis, Mycobacterium avium-intracllulare complex, Mycobacterium leprae  
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Mycobacterium tuberculosis: Labs   Acid fast stain of sputum smear, CXR, PPD, Catalase +, Reduces nitrate  
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Mycobacterium tuberculosis: Toxins   Abundant peptide antigens; Survives acidic, alkaline, or drying condition and resists disinfectants; Can have isoniazid resistance  
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Mycobacterium tuberculosis: Diseases   Primary, Secondary, or Miliary Tuberculosis, Extra-pulmonary TB  
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Mycobacterium tuberculosis: Treatment   Isoniazid, Rifampin, Pyrazinamide  
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Mycobacterium tuberculosis: Transmission   Respiratory droplets  
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Mycobacterium tuberculosis: Vaccine   BCG- not available in the U.S.  
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Mycobacterium bovis: Labs   Acid fast stain of sputum smear, Sputum culture, CXR, Positive PPD  
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Mycobacterium bovis: Toxins   Multiple peptide antigens; Survives acidic, alkaline, or drying conditions and resists disinfectants  
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Mycobacterium bovis: Diseases   Tuberculosis  
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Mycobacterium bovis: Treatment   Isoniazid, Rifampin, Pyrazinamide  
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Mycobacterium bovis: Transmission   Ingestion of raw milk; respiratory droplets  
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Mycobacterium avium-intracellulare complex: Labs   Acid fast stain of sputum smear, Sputum cultures, CXR; PPD may be positive  
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Mycobacterium avium-intracellulare complex: Toxins   Opportunistic pathogen; Survive in acidic, alkaline, and drying conditions  
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Mycobacterium avium-intracellulare complex: Diseases   Pulmonary infections, especially in immunocompromised patients; Disseminates to every organ and can be fatal in months  
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Mycobacterium avium-intracellulare complex: Treatment   Rifampin, Ethambutol, Streptomycin  
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Mycobacterium avium-intracellulare complex: Transmission   Opportunistic infection  
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Mycobacterium leprae: Labs   Lepromin skin test, Serology  
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Mycobacterium leprae: Toxins   Capsule, Intracellular survival within skin histocytes and Schwann cells  
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Mycobacterium leprae: Diseases   Tuberculoid Leprosy, Lepromatous Leprosy, Borderline Leprosy  
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Mycobacterium leprae: Treatment   Dapsone, Rifampin, Clofazime  
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Mycobacterium leprae: Transmission   Respiratory droplets, Close personal contact, Dermal trauma  
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Created by: vmed
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