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Gram positive, Acid fast bacteria, Obligate Aerobic Intracellular

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Gram +, Acid fast bacteria   Mycobacterium tuberculosis, Mycobaterium bovis, Mycobacterium avium-intracllulare complex, Mycobacterium leprae  
Mycobacterium tuberculosis: Labs   Acid fast stain of sputum smear, CXR, PPD, Catalase +, Reduces nitrate  
Mycobacterium tuberculosis: Toxins   Abundant peptide antigens; Survives acidic, alkaline, or drying condition and resists disinfectants; Can have isoniazid resistance  
Mycobacterium tuberculosis: Diseases   Primary, Secondary, or Miliary Tuberculosis, Extra-pulmonary TB  
Mycobacterium tuberculosis: Treatment   Isoniazid, Rifampin, Pyrazinamide  
Mycobacterium tuberculosis: Transmission   Respiratory droplets  
Mycobacterium tuberculosis: Vaccine   BCG- not available in the U.S.  
Mycobacterium bovis: Labs   Acid fast stain of sputum smear, Sputum culture, CXR, Positive PPD  
Mycobacterium bovis: Toxins   Multiple peptide antigens; Survives acidic, alkaline, or drying conditions and resists disinfectants  
Mycobacterium bovis: Diseases   Tuberculosis  
Mycobacterium bovis: Treatment   Isoniazid, Rifampin, Pyrazinamide  
Mycobacterium bovis: Transmission   Ingestion of raw milk; respiratory droplets  
Mycobacterium avium-intracellulare complex: Labs   Acid fast stain of sputum smear, Sputum cultures, CXR; PPD may be positive  
Mycobacterium avium-intracellulare complex: Toxins   Opportunistic pathogen; Survive in acidic, alkaline, and drying conditions  
Mycobacterium avium-intracellulare complex: Diseases   Pulmonary infections, especially in immunocompromised patients; Disseminates to every organ and can be fatal in months  
Mycobacterium avium-intracellulare complex: Treatment   Rifampin, Ethambutol, Streptomycin  
Mycobacterium avium-intracellulare complex: Transmission   Opportunistic infection  
Mycobacterium leprae: Labs   Lepromin skin test, Serology  
Mycobacterium leprae: Toxins   Capsule, Intracellular survival within skin histocytes and Schwann cells  
Mycobacterium leprae: Diseases   Tuberculoid Leprosy, Lepromatous Leprosy, Borderline Leprosy  
Mycobacterium leprae: Treatment   Dapsone, Rifampin, Clofazime  
Mycobacterium leprae: Transmission   Respiratory droplets, Close personal contact, Dermal trauma  


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Created by: vmed on 2007-07-17

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