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Gram - Rods, Aerobic Intracellular

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Gram - Rods, Aerobic Intracellular   Shigella, Salmonella, Legionella pneumophila  
Salmonella typhi/paratyphi: Labs   Oxidase -, Methyl red +, Non-lactose fermenting  
Salmonella typhi/paratyphi: Toxins   Lipopolysaccharide, O-, H-, and K-antigens; Can survive within macrophages and invaced the mucous layer; Beta-Lactamases, Acetlytransferase  
Salmonella typhi/paratyphi: Diseases   Enteric fever (Typhoid fever, Bacteremia, Osteomyelitis; Can cause Reiter's Syndrome and can also lead to abortion in pregnancy  
Salmonella typhi/paratyphi: Treatment   Fluid and electrolytes, Ciprofloxacin, Trimethoprim-Sulfamethoxazole  
Salmonella typhi/paratyphi: Transmission   Human GI tract reservoir with fecal-oral transmission  
Shigella: Labs   Oxidase -, Non-lactose fermenting  
Shigella: Toxins   Shiga toxin (Inhibits protein synthesis), Lipopolysaccharide, Invasion factor  
Shigella: Diseases   Bacillary Dysentery (bloody diarrhea), HUS; Associated with Reiter's Syndrome  
Shigella: Treatment   Trimethoprim-Sulfamethoxazole,Ciprofloxacin, Ceftriaxone, Fluid and electrolytes  
Shigella: Transmission   Human GI tract reservoir; Fecal-oral transmission  
Salmonella: enteritidis: Transmission   Animal reservoir; Fecal-oral transmission; raw eggs, milk, and chicken  
Legionella pneumophila: Labs   Catalase positive; produce brown pigment on culture  
Legionella pneumophila: Toxins   Lipopolysaccharide, Proteolytic enzymes, Beta-lactamase +; Can prevent the fusion of phagolysosomes  
Legionella pneumophila: Diseases   Legionnaire's disease (atypical pneumonia), Pontiac fever  
Legionella pneumophila: Treatment   Erythromycin, Azithromycin, Levofloxacin  
Legionella pneumophila: Transmission   Air conditioners, whirlpool baths, humidifiers, contaminated water; Inhalation of aerosols  


   


 

 

 

 

 

 
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