Gram - Rods, Aerobic, Extracellular
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Gram - Rods, Aerobic extracellular | Haemophilus influenzae, Bordetella pertussis, Yersinia enterocolitica, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus mirabilis
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Haemophilus influenzae: Labs | Catalase +, Oxidase -, ferments glucose (only)
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Haemophilus influenzae: Toxins | Lipopolysaccharide endotoxin, capsule, IgA protease, Beta-lactamase
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Haemophilus influenzae:Treatment | Ceftriaxone, Chloramphenicol, rifampin; Immediate intubation for epiglottitis
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Haemophilus influenzae:Diseases | Pneumonia, Meningitis, Epiglottitis, Sinusitis, Otitis media, Purulent conjunctivitis
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Haemophilus influenzae: Transmission | Respiratory droplets
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Haemophilus influenzae: Vaccine | Hib
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Bordetella pertussis: Labs | Oxidase +, Agglutinin reaction positive, Direct fluorescent antibody test
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Bordetella pertussis: Toxins | Pertussis toxin , adenylate cyclase toxin, lipopolysaccharide, Capsule, Filamentous Hemaglutinin
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Bordetella pertussis: Diseases | Whooping cough
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Bordetella pertussis: Treatment | Erythromycin
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Bordetella pertussis: Transmission | Respiratory droplets
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Bordetella pertussis: Vaccine | DTaP
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Yersinia enterocolitica: Labs | Oxidase -, Catalse +, Urease +
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Yersinia enterocolitica: Toxins | Lipopolysaccharide, O-antigens, H-antigens; Can grown in cold conditions
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Yersinia enterocolitica: Diseases | Enterocolitis (bloody diarrhea)/ Typhoid, Bacteremia and Sepsis; Associated with Reiter's Syndrome
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Yersinia enterocolitica: Treatment | FEN, Gentamicin
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Yersinia enterocolitica:Transmission | Animal reservoir; transmitted from unprocessed milk, raw meat, contaminated water
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Pseudomonas aeruginosa: Labs | Oxidase +; Blue/green colonies with a fruity odor
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Pseudomonas aeruginosa: Toxins | Exotoxin A, Exoenzyme S, Hemolysins, Lipopolysaccharide, Glycocalyx, Elastase, Multidrug Resistance factors
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Pseudomonas aeruginosa: Diseases | Pneumonia in the immunocompromised, Burn wound infections, Endocarditis in IV drug users, Nosocomial UTI, Bacteremia leading to septic shock, Corneal keratitis, Otitis externa (swimmer's ear)
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Pseudomonas aeruginosa: Treatment | Aminoglycoside + Beta-Lactam, Cefepime, Piperacillin, Aztreonam
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Pseudomonas aeruginosa: Transmission | Colonizes in water or wet areas
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Klebsiella pneumoniae: Labs | Oxidase -, Lactose fermenting, Urease +
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Klebsiella pneumoniae: Toxins | Lipopolysaccharide, Capsule, Beta-lactamase+
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Klebsiella pneumoniae: Diseases | Pneumonia, Nosocomial UTI, Bacteremia
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Klebsiella pneumoniae: Treatment | 3rd generation cephalosporin plus an aminoglycoside, Cefepime
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Klebsiella pneumoniae: Transmission | Normal colon flora, but also nosocomial transmission with in-dwelling catheters and endotracheal tubes
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Proteus mirabilis: Labs | Oxidase -, Non-lactose fermenting, Urease +
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Proteus mirabilis: Toxins | Lipopolysaccharide, Urease, Strong motility with flagella
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Proteus mirabilis: Diseases | UTI, Nephrolithiasis (Struvite stones)
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Proteus mirabilis: Treatment | Ampicillin for cystitis, Ciprofloxacin
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Proteus mirabilis: Transmission | Normal colon flora; Nosocomial catheter infection
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