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Gram - Rods, Aerobic, Extracellular

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Gram - Rods, Aerobic extracellular   Haemophilus influenzae, Bordetella pertussis, Yersinia enterocolitica, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus mirabilis  
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Haemophilus influenzae: Labs   Catalase +, Oxidase -, ferments glucose (only)  
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Haemophilus influenzae: Toxins   Lipopolysaccharide endotoxin, capsule, IgA protease, Beta-lactamase  
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Haemophilus influenzae:Treatment   Ceftriaxone, Chloramphenicol, rifampin; Immediate intubation for epiglottitis  
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Haemophilus influenzae:Diseases   Pneumonia, Meningitis, Epiglottitis, Sinusitis, Otitis media, Purulent conjunctivitis  
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Haemophilus influenzae: Transmission   Respiratory droplets  
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Haemophilus influenzae: Vaccine   Hib  
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Bordetella pertussis: Labs   Oxidase +, Agglutinin reaction positive, Direct fluorescent antibody test  
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Bordetella pertussis: Toxins   Pertussis toxin , adenylate cyclase toxin, lipopolysaccharide, Capsule, Filamentous Hemaglutinin  
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Bordetella pertussis: Diseases   Whooping cough  
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Bordetella pertussis: Treatment   Erythromycin  
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Bordetella pertussis: Transmission   Respiratory droplets  
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Bordetella pertussis: Vaccine   DTaP  
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Yersinia enterocolitica: Labs   Oxidase -, Catalse +, Urease +  
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Yersinia enterocolitica: Toxins   Lipopolysaccharide, O-antigens, H-antigens; Can grown in cold conditions  
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Yersinia enterocolitica: Diseases   Enterocolitis (bloody diarrhea)/ Typhoid, Bacteremia and Sepsis; Associated with Reiter's Syndrome  
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Yersinia enterocolitica: Treatment   FEN, Gentamicin  
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Yersinia enterocolitica:Transmission   Animal reservoir; transmitted from unprocessed milk, raw meat, contaminated water  
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Pseudomonas aeruginosa: Labs   Oxidase +; Blue/green colonies with a fruity odor  
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Pseudomonas aeruginosa: Toxins   Exotoxin A, Exoenzyme S, Hemolysins, Lipopolysaccharide, Glycocalyx, Elastase, Multidrug Resistance factors  
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Pseudomonas aeruginosa: Diseases   Pneumonia in the immunocompromised, Burn wound infections, Endocarditis in IV drug users, Nosocomial UTI, Bacteremia leading to septic shock, Corneal keratitis, Otitis externa (swimmer's ear)  
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Pseudomonas aeruginosa: Treatment   Aminoglycoside + Beta-Lactam, Cefepime, Piperacillin, Aztreonam  
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Pseudomonas aeruginosa: Transmission   Colonizes in water or wet areas  
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Klebsiella pneumoniae: Labs   Oxidase -, Lactose fermenting, Urease +  
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Klebsiella pneumoniae: Toxins   Lipopolysaccharide, Capsule, Beta-lactamase+  
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Klebsiella pneumoniae: Diseases   Pneumonia, Nosocomial UTI, Bacteremia  
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Klebsiella pneumoniae: Treatment   3rd generation cephalosporin plus an aminoglycoside, Cefepime  
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Klebsiella pneumoniae: Transmission   Normal colon flora, but also nosocomial transmission with in-dwelling catheters and endotracheal tubes  
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Proteus mirabilis: Labs   Oxidase -, Non-lactose fermenting, Urease +  
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Proteus mirabilis: Toxins   Lipopolysaccharide, Urease, Strong motility with flagella  
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Proteus mirabilis: Diseases   UTI, Nephrolithiasis (Struvite stones)  
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Proteus mirabilis: Treatment   Ampicillin for cystitis, Ciprofloxacin  
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Proteus mirabilis: Transmission   Normal colon flora; Nosocomial catheter infection  
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