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Gastrointestinal disorders

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Disease
Characteristics
Notes
Achalasia   impaired esophageal peristalsis / lower esophageal sphincter contraction   age 20-40, dysphagia-soilds & liquids, chest pain, regurgitation, nocturnal cough  
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Plummer Vinson   mucosal membrane across lumen   aka Paterson-Kelly "Irish Plumber" so you have "webs in your pipes"  
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Esophageal varices   varicosities in the esophagus   portal hypertension  
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Gastroesophageal Reflux "GERD"   incompetence of lower esophageal sphincter   reflux gastric contents, Barrett's Esophagus  
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Esophageal Diverticula   outpouching of the mucosa & submucosa posteriorly - BAD BREATH   aka Zenker's fills with food, possible regurgitation when bending or lying down  
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Mallory-Weiss   laceration of distal esophagus & proximal stomach during vomiting, retching, or hiccups   hemorrhage - alcoholics  
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Duodenal Ulcers   located at the beginning of the small intestine, burning or gnawing pain, vomiting   Most common ulcer  
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Gastric ulcer   located along the lesser curvature of the stomach   caused by helicobacter pylori & NSAIDS  
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Cancer of stomach   occurs most frequently at the greater curvature of stomach   unexlpained weight loss, unrelenting pain  
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Hepatitis   inflammation of the liver   inflammation of the liver  
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Cirrhosis   secondary to chronic alcohol abuse   fatty liver  
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Diverticulum   a pouch or sac through a defect   a pouch or sac through a defect  
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Diverticulosis   presence of diverticula, no inflammation   presence of diverticula, no inflammation  
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Diverticulitis   inflammation of diverticular mucosa   inflammation of diverticular mucosa  
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Ulcerative Colitis   mucosal ulcerations, watery stool   episodic, bloddy diarrhea, fever  
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Irritable Bowel Syndrome   gas & distention, pencil-thin stools   episodic, consitpation and diarrhea  
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Crohn's   skip lesions, distal ileum, colon   aka regional enteritis chronic diarrhea, fever, anorexia  
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Hirschsprung's   congenital avsence of Meissner's & Auerbach's automomic plexus   aka congenital megacolon could be fatal if not diagnosed  
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Celiac Disease   hereditary, chronic intertinal malabsorption causeing mucosal damage   gluten "wheat" intolerance, pt has steatorrhea (floating feses)  
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tropical Sprue   mucosal abnormalities in small bowel   sore tongue, diarrhea, weight loss  
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Whipple's Disease   small bowel infection - professive & fatal   30-60 males, anemia, weight loss, skin pigmentation, diarrhea, joint, cough  
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Zollinger-Ellison   Aggressive peptic ulcer / tumor   can perforate through the lining  
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Gardener's syndrome   found in the ascending colon   produces polyps  
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