Biochem Exam
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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NAD Vitamin | Niacin (B3)
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FAD Vitamin | Riboflavin (B2)
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TPP Vitamin | Thiamine (B1)
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CoA vitamin | Pantothenate (B5)
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Folic Acid | Tetrahydrofolate
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Pyroxidal Phosphate | Pyridoxine (B6)
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Vmax | max velocity of a rxn
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Km | concentration of substrate
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Kd | measure of binding
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Competitive Inhibitor | binds substrate binding site, decrease rxn rate, increased km
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Non-Competitive Inhibitors | binds allosteric substrate,
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GLUT 1 | highly expressed in erythrocytes and high affinity for glucose
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GLUT 2 | low affinity transporter, liver
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GLUT 3 | high affinity transporter, brain
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GLUT 4 | insulin sensitive, adipose and muscle
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VIII | stimulates platelet degredation, activates 10, activated by thrombin
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X | stimulates prothrombin to thrombin
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III | Tissue factor, activates 7
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VII | beginas cascade based on trauma
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XIII | crosslinks (hard clot formation)
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V | activated by thrombin, cofactor to 10 to change prothrombin to thrombin
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Fibrinogen | with thrombin (2a) causes fibrin to form soft clot
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Thrombin | activates 11
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coagulation cofactors | 8 and 5
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Externsic Pathway | 3-7-10
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Intrinsic | 12-11-9 (with 8)-10
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aPTT | intrinsic and common pathway
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PTT | extrensic and common pathway
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Hemophilia A | deficiet factor 8
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Hemophilia B | deficit factor 9
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Heparin | blocks coagulation by inhibiting factor 2 (AKA Thrombin)
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Inhibitors of Coagulation | Protein S, C, Serpins, Heparin
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type I collagen | main type
CT, bone, teeth, encapsulated organs
resist force, tension and stretch
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type II collagen | cartilage
resists intermittent pressure
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Type III Collagen | found in reticular fibers
scaffolding for specialized cells
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Type IV Collagen | basement membrane
suppoer and filtration
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Type VII Collagen | skin, eye, etc
connects basement membrane to ECM
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Mast Cells | allergies-secrete histamine and heparin
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Plasma Cells | produce antiboides, made in marrow
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Anaphylaxis | hypersensitivity to histamine, drop in BP and close airways
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histamine | increases contratcion of vessels, permeability of vessels and mucous production
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MMP (metalloprotesases) | breaksdown damaged fibers via phagocytosis
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apocrine sweat glands | 3 A's:axilary, anal, aerolar
ducts
secrete via exocytosis
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eccrine sweat glands | watery secretion and ducts
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sebaceous glands | oily substance to hair follicles
whole cells into gland
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Pilosebaceous unit | hair shaft, sebaceous gland, arrector pili muscle, hair follicle and hair root
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Basal Cell Carcinoma | arises from follicular bulge of hair
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defect that leades to albinism | lack of tyrosinase
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Central canal of bone includes | vein, artery, and nerve
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