Worsham Path Q2
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pathology | the study of disease-specifically the study of the structure and function of the body as it is affected by disease
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where does the term pathology come from | Greek word for disease or suffering (pathos) and the word for science or "study of" (logos)
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when does the field of pathology come into play | when structure and function are no longer "normal"
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who is the "father of medicine" | the Greek physician Hippoctrates (460-359BC)
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gross pathology | studies changes in the structure and function of the body which can be observed with the unaided eye
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microscopic, cellular or histo-pathology | studies changes which occur in cells of the body at the microscopic level
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general pathology | deal with general or broad disease processes, such as necrosis or inflammatin, which may affect the entire body or wide-spread tissues and organs
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special pathology | studies disease processes affecting individual body areas or systems, such as pathology of the respiratory system or diseases of the skin
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pathological anatomy | study of tissues which have been removed from the body for patholoical study
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tissuses removed during surgery or a biopsy is also known as | surgical pathology
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autopsy pathology | tissues removed during autopsy
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clinical pathology | deals with the laboratory study of, and the performance of standardized tests on, body fluids, and secretions, such as blood and urine tests, or cultures and smears of various types
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physiological pathology | refers to studying the functional changes in the body resulting from disease
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medical-legal pathology (forensic pathology) | that field of pathology which deals with both the medical and legal issues surrounding death
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autopsy (postmortem examinaion; necropsy) | from the Greek words for "self" and "sight", used to refer to the examination of the body after death in order to determine the cause of death and/or existence of various disease conditions
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translation of necropsy | "a state of death"
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disease | any change in the structure or function of the body as a result of injury to the tissues
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acute | rapid onset-short duration
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chronic | gradual onset-long duration
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fulminating disease | acute disease that ends in death
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recurrent disease | symptoms and signs of a disease reappear after a period of remission
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infectious disease | disease caused by a living pathogenic microorganism; transmitted from person to person
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contagious (communicable) | diseases which are easily transmitted from person to person
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infestation | refers to the presence of macroscopic organisms in or on the body (animal parasites, fleas, ticks)
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idiopathic | cause of disease is not known
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occupational | disease results from the nature of one's working conditions (coal minners disease-black lung)
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endemic | dieases which are always present to some degree in a given area or community
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sporadic | diseases which are found to occur only occasionally in a community
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epidemic | diseases which affect a much larger than normal number of people in a community at one time
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pandemic | diseases which affect the majority of the population in a very large area, possibly even worldwide
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prevalence | refers to the number of cases of a disease within a certain population at a given time
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acquired disease | development of a disease after birth
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congenital disease | present at or before birth
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hereditary disease | disease transmitted from parent to offspring
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all genetic diseases are | hereditary
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not all hereditary diseases are | genetic
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febrile disease | disease characterized by the presence of a fever
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intoxication | the state of being poisoned
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deficiency disease | disease caused by the lack of some essential element
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iatrogenic | one which results from a physicians treatment of a patient
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malformations or anomalies | any defect in formation, structure or position of the body part. (something other then normal-no matter how small or large)
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aplasia | absence of a body part
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hypoplasia | under development of a body part
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spina bifada | defect in the walls of the lower part of the spinal column
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polydactylism | excess number of fingers or toes
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hernia | protrusion of an organ through the wall of the body cavity in which it is contained
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fistula | abnormal tract or channel through the tissues, connecting one body cavity with another, or connecting a cavity with the surface of the body
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cyst | sac-like structure, containing fluid or a semi-solid substance. (abnormal debelopment of tissues, obstruction of ducts or infections)
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Down's Syndrome (mongolism) | genetic defect resulting in various degrees of mental retardation, a dwarfed physique, and certain characteristic abnormalities of the head and extremities
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lesion | any change produced by a disease (cold sore, peptic ulcer, broken bone, abscess, chancre)
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organic diseases | disease have readily identifiable characteristic lesions (swollen & inflamed mucous membranes, ulcerations of syphilis)
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functional disease | disease with no apparent underlying organic disorder
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symptom | subjective manifestation of a disease. Those things which cannot be measured such as pain or malaise ("just don't feel good")
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sign | objective manifestation of disease. Those things which can be measured such as blood pressure, body temperature, swelling, heart rate
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syndrome | group of signs and symptoms that occur together. The sum of the signs and syptoms of any pathological condition
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diagnosis | the determination of what disease exists. Analysis of patient history, signs, symptoms, and results of tests ordered by the physician
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differential diagnosis | the process by which a physicain will rule out certain diseases with similar signs and symptoms so that an accurate determination can be made
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prognosis | prediction of the outcome of a disease
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remission | abatement; temporary or permanent disappearance of signs and symptoms
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exacerbation | a sudden increase in the severity of signs and symptoms
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complication | any unfavorable condition that may arise during a disease (hemorrhage resulting from duodenal peptic ulcer)
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etiology | cause of the disease (specifically, the study of the cause of disease
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pathogenesis | development of a disease, what it causes, what changes it produces, and how it affects the structure (morphology) and function (physiology) of the part or organ involved and the body as a whole
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what are 6 predisposing factors for diseases | age, race, gender, genetics, occupation, environment
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whar are 7 immediate/existing cause of disease | trauma, physical agents, chmical agents, living agents, deficiencies, allergens, heredity
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sequelae | remote aftereffects of disease. May appear 20 to 30 years after the acute stage
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intercurrent disease | disease that arises during the course of another disease (patient with cancer myocardial infarction)
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non-suppurative disease | non-spus forming
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communicable disease | disease that can be transmitted from one person to another
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allergy | a state of hypersensitivity of the immune system; an overreaction to a harmless substance called allergen
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functional disease | disease with no apparent underlying organic disorder (phobias)
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inflammation | body's response to tissue injury
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it is not a diaease, but a process the body goes through in response to an injury | inflammation
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inflammation can be thought of as a | defense mechanism
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the 3 purposes of inflammation are | 1-limit extension of this injurious, 2-destroy & remove the injurious agent, 3-mechanism for allowing the body to repair itself & return the injured tissues to normal use
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four common causes of inflammation | living agents, chemical irritants, physical irritants, immunological reactions
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inflammatory response is initiated when | injured and dying cells release chemical substances into the surrounding tissues which in turn stimulate other events to occur
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no matter the cause of inflammation the common underlying situation is | damage to bodily tissues
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in an attempt to isolate infection capillaries become ______ permeable, leaking additional fluid, which carry _______ and ______ _______ | more, antibodies, plasma proteins
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plasma proteins are involved in | blood clot formation (fibrin formation)
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exudates | excess fluids which collect around an inflammation site may be thought of as a type of edema
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exudates may be categorized based on the substances they contain, which would be | purulent or suppurative (pus), hemorrhagic (blood), serous (clear liquid portion of the blood)
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diapedesis | white blood cells are migrating out of the capillary walls and into the surrounding tissues
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neutrophils | are the most prevalent type of phagocytic white blood cells and they help to ingest invading bacteria and other cellular debris
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the process of pus formation is called | suppuration
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bacteria which cause suppuration are called | pyogenic
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what are 5 signs of cardinal inflammation | heat (calor), redness (rubor), pain (dolor), swelling (tumor), altered function
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which sign of inflammation is associated with extra blood flow | heat and redness
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swelling is | additional blood flow and presence of exudates
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pain associated with inflammation is | pressure on sensory nerve endings in the vicinity of the inflammation
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altered function can be the result of | any combinaiton of calor, rubor, dolor or tumor
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what are the 6 common lesions associated with inflammation | abscess, ulcer, vesicle, pustule, furuncle, carbuncle
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abscess | an area of pus surrounded by wall of inflammatory tissue
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ulcer | a localized area of necrosis on the skin or mucous membranes
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vesicle | an elevation of the skin containing fluid
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pustule | an elevation of the skin containing pus
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furuncle | boil; an abscess located in the deeper layers of the skin
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carbuncle | 2 or more communicating furuncles; often accompanied by fever, leukocytosis, weakness, fatigue
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when the inflammatory process has mangaged to overcome the injurious agent the next step is | tissue repair
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repair | refers to the replacement of damaged tissue with connective tissue
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scar or cicatrix | involves the formation of fibrous connective tissue
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regeneration | refers to the replacement of damaged tissue with identical tissue
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tissues of the body have equal or varying regenerative capacities | varying
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resolution | indicate the termination of an inflammatory reaction, with the body part returned to normal use
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what are the 2 main implications of inflammation | 1-skin burns, infectious lesions 2-internal inflammorty condition
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how to overcome skin burns and infectious lesions | cosmetic civering of minor discolorations, excision of cebrotic tissue, surface compresses, hypodermic injection to supplement arterial injection
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how to overcome internal inflammatory condition | higher fluid content in localized areas of inflammation
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