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Lecture Unit 2

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Question
Answer
The Nervous System   Body's primary communication & control system. Other control system is the Endocrine system.  
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Structural Organization of the Central Nervous System (CNS)   Brain, Spinal cord  
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Structural Organization of the Peripheral Nervous System (PNS)   (All Nerves) Cranial nerves-12 pairs, Spinal nerves-31 pairs, Ganglia (mass of cell bodies).  
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Functional Organization   Sensory (Afferent) Division and Motor (Efferent) Division. SAME DAVE.  
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Sensory (Afferent) Division   Transmit information FROM RECEPTORS TO CNS. Divided into somatic and visceral sensory.  
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Motor (Efferent) Division   Transmit information FROM CNS TO MUSCLE OR GLAND. Divided into somatic and autonomic motor.  
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Somatic Sensory   Receives sensory information form skin, fascia, joints, skeletal muscles, special senses.  
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Visceral Sensory   Receives sensory information from viscera.  
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Somatic Motor   VOLUNTARY. Nervous system: innervates skeletal muscle  
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Autonomic motor   INVOLUNTARY. Nervous system: innervates cardiac muscle, smooth muscle, glands. Further divided into sympathetic and parasympathetic.  
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Cytology of Nervous Tissue   Neurons: Excitable cells that transmit nerve impulses. Glial cells: Non-excitable cells that support and protect the neurons. Nerve glue.  
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Neuron Characteristics   High metabolic rate-need constant glucose and oxygen. Longevity-live and function for over 100 years. Only cells like this. Nonmitotic-during fetal development lose ability to divide.  
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Primary tumor of the CNS   May form in the meninges (meningiomas) or glial cells (gliomas). Neurons incapable of becoming tumors-can't divide. These tumors originate w/i the brain. Brain tissue is the source.  
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Secondary tumor of the CNS   Forms in another site but spreads to the brain (lung, skin, or breast cancers).  
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Neuron anatomy   Dendrites, Cell body, nucleus, Axon hillock, Axon, Neurofibril node (Node of Ranvier), Myelin sheath, Synaptic knobs. Be able to label picture! Know pathway!  
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Dendrites   Carry impulses towards the cell body. Soma can have only one or many dendrites. Receive input and transfer to cell body for processing.  
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Cell Body   AKA: Soma. Neuron control center. Contains nucleus and organelles. Comprise "gray matter." Form clusters in PNS called ganglia. Form clusters in CNS called nuclei.  
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Axons   Most neurons have 1 axon (anaxonic neurons have none). AKA nerve fiber. Carry impulses away from cell body to another cell. Transmits its output info to other cells. Ends branch into synaptic knobs.  
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Structural Neuron Classification   How many structures come off cell body. Unipolar-sensory afferent neurons Bipolar-special senses, uncommon in humans. Multipolar-motor efferent neurons. Most common type.  
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Functional Neuron Classification   Sensory (afferent)-from sensory receptors to CNS. Dorsal side. Interneurons-lie between motor and sensory neurons; entirely confined to CNS. Motor (efferent)-From CNS to muscles or glands. Ventral side of spinal cord. Be able to label picture!  
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Glial Cells of the CNS (4)   Astrocyte, Ependymal cell, Microglial cell, Oligodendrocyte  
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Astrocyte   CNS. Star cell. Control ionic environment. Helps form blood-brain barrier. Babysits neuron. Intermediate between blood and neuron.  
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Ependymal cell   Lining ventricles of CNS. Help produce and circulate cerebral spinal fluid (CSF). CSF is clean, filtered plasma.  
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Microglial cell   Macrophages of CNS. Immune cell.  
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Oligodendrocyte   Forms myelin sheaths in CNS on more than one neuron. One cell myelinates multiple axons. Extensions create myelin sheath.  
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Glial Cells of the PNS (2)   Satellite cell, Neurolemmocyte.  
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Satellite cell   Dorsal root ganglia of PNS. Protects and regulates nutrients for cell bodies in ganglia. Protects and provides nutrients for soma.  
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Neurolemmocyte   AKA Schwann cell. Myelinates PNS axons. Is Myelin sheath of PNS. No extensions. Cell wraps around axons and becomes myelin sheath. Myelinates 1 section of 1 axon.  
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Myelin Sheath   Made by oligodendrocytes in the CNS & neurolemmocytes (schwann cells) in the PNS. Protective, white, fatty coating. Supports, protects, & insulates axon. Increases speed of conduction-nerve impulses jump from node to node. Neurofibril nodes (of Ranvier)  
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Nerves   Neurons traveling together. A cable-like bundle of parallel axons.  
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Three connective tissue wrappings of nerves   Endoneurium-surrounds individual axon. Perineurium-surrounds individual fascicles. Epineurium-surrounds whole nerve.  
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Synapses   Site at which neurons communicate with other neurons, glands, or muscles.  
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Parts of Synapses   Preynaptic neuron (Neuron before synapse). Synaptic vesicles contain neurotransmitters. Synaptic cleft (space in between). Postsynaptic neuron (Whatever connected to on other side). Label!!  
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Amyotrophic Lateral Sclerosis   ALS or Lou Gehrig Disease. Fatal degeneration of the somatic motor system. Atrophied muscles cause breathing, speaking, & swallowing difficulties. No effective treatment or cure. Doesn't affect mind. Trapped. Cause of death: diaphragm goes-can't breathe.  
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Multiple Sclerosis   Autoimmune disease. Patches of myelin in brain and spinal cord destroyed. Affects 1/1000 people. Symptoms: blindness, weakness, clumsiness. nervous system full of scars. Symptoms wax and wane. Vary from person to person-how many neurons involved.  
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Anencephaly   Disorder at the cranial end of the neural tube. Substantial or complete absence of a brain-only brain stem forms. Infants rarely live longer than a few hours following birth. Usually detected w/ prenatal ultrasound. Most miscarry.  
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Spina Bifida   Disorder at the caudal end of the neural tube. Vertebral arch is not fully formed. Mild: spina bifida occulta. Severe: spina bifida cystica. Increased intake of Vit B12 & folic acid of pregnant women decreases incidence.  
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