Lipoproteins...
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Site of production of chylomicron | Small intestine
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| Site of production of HDL | Liver
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| Site of production of VLDL | Liver
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| Process of atherosclerosis | VLDL "loses" triacylglycerols to tissues -> becomes denser (LDL) -> Too much LDL in the blood -> acumulation of LDL in vessels' walls -> attracts WBC -> plaque formation (stenosis) -> calcium coating -> hardening of the vessel -> atherosclerosis
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| Familial hypercholesterolemia | Genetic disorder -> LDL receptors don't function properly -> high LDL levels in the blood
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| Enzyme responsible for the transference of membrane cholesterol to HDL | Flippase
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| Tangier disease | Flippase genetic disorder -> low HDL levels
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| Transport of cholesterol from intestine to liver | Chylomicrons
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| Transport of cholesterol from liver to tissues | VLDL and LDL
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| Transport of cholesterol from tissues to liver (reverse transport) | HDL
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| Why do atherosclerotic plaques tend to form preferably in the aortic arch? | High pressure = increased permeability to macromolecules
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Created by:
gabrielbianco
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