OPT Viral
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human herpes virus | family of 8 viruses causing a myriad of diseases
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primary herpes simplex | in previously unexposed individuals after 3-9 days post-exposure
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acute herpetic gingivostomatitis | most common form of primary herpes simplex; fever, crops of oral vesicles that coalesce and painful, enlarged marginal gingiva
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herpes viral cytopathic effect | nuclear swelling, margination of chromatin, and fusion of cells forming multi-nucleated giant cells
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recurrent herpes simplex | the herpes virus after it has been transported to sensory ganglia and remains latent unless reactivated
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herpes labialis | recurrent herpes simplex at vermillion border aka {cold sore/fever blister}
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recurrent herpes simplex virus | lesions limited to keratinized mucosa bound to bone (distinguishes from apthous ulcers)
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herpetic whitlow | herpes simplex infections on fingers and thumbs
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varicella (chickenpox) | caused by {Varicella zoster virus}; primary infection is {chicken pox} and recurrent infection is {herpes zoster/shingles}
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Varivax | universal vaccine for VZV
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breakthrough infection | outbreak of chickenpox or shingles in immunized patients; most cases today are of this type
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VariZIG | vaccine for infants and immunocompromised for VZV
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MMR-Proquad | vaccine for VZV, measles, mumps, rubella
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herpes zoster | virus that travels up sensory nerve to dorsal spinal ganglia that can be reactivated to secondary infection
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acute phase of herpes zoster | phase of herpes zoster that follows prodrome; skin rash of vesicles that stop at the midline
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Ramsay Hunt Syndrome | reactivation of VZV in geniculate ganglion; ear problems, facial paralysis like Bell's palsy and vertigo
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post-herpetic neuralgia | chronic phase of herpes zoster, pain that persists in area of the skin rash
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granulomatous angiitis | ischemic stroke syndrome from inflammation of internal carotid artery; associated with herpes zoster
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Zostavax | vaccine for people 50+ for VZV
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infectious mononucleosis | caused by {Epstein-Barr virus}; causes fatigue, lymphadenopathy, NUG
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mono-spot assay and Paul Bunnell test | tests for heterophile antibodies to EBV
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cytomegalovirus (CMV) | usually asymptomatic but has symptoms like mononucleosis in immunocompromised
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herpangina | caused by Coxsackie virus A; flu-like symptoms and palatal macules
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hand-foot-and-mouth disease | mostly caused by Coxsackie A16; oral lesions appear first then rupture to form ulcers
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acute lymphonodular pharyngitis | yellow/pink lymphoid aggregates on palate and tonsils
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measles (rubeola) | highly contagious infection caused by {Paramyxovirus} family; coryza, conjunctivitis, and cough
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Koplik's spots | oral lesions that develop before the skin rash of measles; blue/white macules on mucosa
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Rubella (German measles) | mild form of measles caused by members of {Togavirus}
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congenital rubella syndrome (CRS) | occurs in fetuses exposed to rebella first 12 weeks; deafness, heart disease, and cataracts
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mumps (epidemic parotitis) | caused by members of {Paramyxovirus} affecting the parotid glands
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cART (combined antiretroviral therapy) | drug regimen for HIV/AIDS; has greatly reduced mortality
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acute retroviral syndrome | after initial exposure to HIV, self-limited illness with mono symptoms
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AIDS-related complex (ARC) | before full-blown AIDS; lymphadenopathy, fever, weight loss, hairy leukoplakia
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candidiasis | most common oral manifestation of HIV
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oral hairy leukoplakia | white mucosal plaque that does not rub off on lateral borders of tongue; associate with EBV
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morsicatio | frictional hyperkeratosis from chronic oral trauma
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Kaposi's sarcoma | multifocal vascular neoplasm caused by HHV-8; defines AIDS in HIV patients
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bacillary angiomatosis | mimics Kaposi's sarcoma, associated with cat scratch disease
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persistent generalized lymphadenopathy (PGL) | enlarged lymph nodes present for longer than 3 months and over 2 sites outside of inguinal region
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non-Hodgkin's lymphoma | most common malignancy in HIV patients; aggressive B-cell lymphoma
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HIV-associated periodontal disease | includes NUG, NUP and linear gingival erythema (an unusual candida infection)
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Created by:
aharnold
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