E coli
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each of the black spaces below before clicking
on it to display the answer.
Help!
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| what are the non-inflammatory E coli illnesses? (do not see fecal WBCs) | Enterotoxigenic (ETEC), Enteropathogenic (EPEC), Enteroaggregative (EAggEC)
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| E coli that cause invasive disease | Enteroinvasive (EIEC), Enterohemorrhagic (EHEC)
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| ETEC characteristics | **traveler's diarrhea** abrupt onset watery diarrhea, lasts 24 hours long after fluids replaced, Toxins
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| ETEC toxins | Heat labile toxin- A-B toxin like cholera......Heat stable toxin- stimulates cGMP and secretes Cl- into the lumen ( osmotic diarrhea)
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| EPEC characteristics (no toxin) | **most common in children**attach to ep cells and disrupt microvilli.. unique type III secretory system
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| EPEC attachment | Tir receptors put in ep cell and intimin put on bacterial cell....causes actin rearrangement a pedestal emerges from the cell
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| EAggEC characteristics | *** persistent diarrhea*** 3 stages (1. adhere to mucous, 2. enhance mucous formation, 3. cytotoxin damages cell)
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| Treatment for inflammatory E. coli infections | replace fluids and antibiotics may help shorten duration
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| EIEC characteristics | similar pathogenesis to Shigella (shiga toxin kills cells, lives intracellularly) watery diarrhea
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| EHEC characteristics | ***most infect large bowel***, kidney damage from shiga toxin, Hemorrhagic colitis or hemolytic uremic syndrome
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| Hemolytic uremic syndrome is.... | triad of symptoms...1. renal failure 2. thrombocytopenia 3. microangiopathic hemolytic anemia
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| diagnosis and treatment of invasive E. coli | EHEC----0157:H7--inability to ferment sucrose----avoid antibioitics (may release more toxin)
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| listeria monocytogenes seen in..... | maternal infection during pregnancy
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Created by:
sambone
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