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Drugs 2 for Biochem Class

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Inhibits complex III (Cytochrome c reductase) of the ETC   Antimycin A  
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Inhibits ATP translocase   Aphidicolin  
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Prevents ATP production by phosphoglycerate kinase   Arsenate  
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Irreversible inhibitor of COX-1   Aspirin  
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Inhibits CPSII, CTP synthetase and PRPP amidotransferase   Azaserine  
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Inhibits carbamoyl phosphate synthetase II   Azaserine  
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Chain terminators to inhibit viral DNA repliation   AZT and didanosine  
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Inhibits Complex IV (Cytochrome oxidase) of the ETC   Cyanide, CO, Azide (N3)  
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Inhibits Na+/K+-ATPase   Digoxin  
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Covalently modifies eEF2, inactivates it and inhibits translation   Diptheria toxin  
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Inhibits Type II topoisomerase in humans   Etoposide  
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Inhibits enolase   Flourine  
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Suicide inhibitor of thymidylate synthase   Fluorouracil  
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Inhibits thymidylate synthase   Fluorouracil  
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An anticancer drug that is a suicide inhibitor of thymidylate synthetase   Fluorouracil  
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This anticancer drug inactivates thymidylate synthetase and therefore inhibits DNA synthesis.   Fluorouracil  
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Effective in the treatment of DVT because it acts to inhibit the activity of thrombin   Heparin  
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Used in the treatment of tuberculosis, this reacts with pyridoxal leading to a B6 deficiency   Isoniazid  
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Inhibits de novo synthesis of purines, thereby inhibitin DNA synthesis.   Mercaptopurine  
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Inhibits aspartate transcarbamoylase (the pyrimidine biosynthetic enzyme) and prevents DNA replication   N-phosphonacetyl-L-aspartate) PALA  
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Irreversible inhibitor of transpeptidase involved in cell wall synthesis   Penicillin  
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These three enzymes inhibit DNA gyrase and prevent the growth of E. coli   Quinolones, nalidixic acid and ciprofloxacin  
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Hydrolyzes 28S RNA and inactivates ribosomes   Ricin  
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Ligand for estrogen receptor   Tamoxifen  
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Vitamin K analog that inhibits the regeneration of Vitamin K   Warfarin (Coumadin)  
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Antibacterial agents which competitively inhibit digydropteroate synthase   Sulfonamides  
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Inhibits dihydrofolate recuctase (DHFR)   Trimethoprim  
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Inhibits ATP Synthase   Oligomyacin  
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