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Contrast Media Worksheet

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
What is the purpose of contrast agents used in diagnostic imaging?   Demonstrates absorption and density differences in organs and vessels  
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Positive contrast agents increase/decrease density differences.   increase  
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What are two examples of positive contrast agents and an exam where they are utilized?   barium sulfite (barium swallow)non iodinated (myelogram)  
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What are two types of negative contrast agents and an exam that uses negative agents?   air, carbon dioxidedouble contrst barium enema  
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Why do we not give a patient barium sulfate if there is a suspected perforation or obstruction?   It may leak into the peritoneal cavity causing infection (peritonitis) or if the patient has an obstruction it may cause more of an obstruction.  
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what type of water soluble contrast is used in cases of perforation of the bowel?   Oral/rectal  
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What is the k edge for barium? iodine?   37; 33  
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By know what the k edge of the contrast is what information do we gain?   we can determine what kVp to use barium - 37 - 105 kVp iodine - 33 - 90-95 kVp  
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Define water soluble   substance that can easily dissolve in water  
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w/w (weight in weight)   amount of solid substance dissolved in known amount of liquid  
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w/v (weight in volume)   amount of solid substance dissolved in measured quantity of liquid  
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Non-ionic, LOCA   low osmolar contrast agent; safer; contains less particles and will not bind within body causing less chances for adverse effects  
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Concentration of ions in a dissolved sutstance per unit of solvent.   osmolarity  
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number of cases of adverse occurences   morbidity  
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death rate   mortality  
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Viscosity   thickness/resistance to flow  
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What is the purpose of single contrast studies and double contrast studies?   single - for filling to identify obstructiondouble - to coat the mucosal lining to look for polyps and ulcers  
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What are two medications given for pre medication for allergy to water soluble iodinated contrast?   prednisone and benadryl  
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What is the advantage of non-ioni, LOCA water soluble contrast media?   fewer iodine particles and no free electrons. It will not bind within body, decreases adverse occurence; less toxic and low morbidity  
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Which contrast would have less toxicity?ionic, low osmolarity, non-ionic low osmolarity or nonionic high osmolarity   non-ionic low osmolarity  
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What is the maximum level for creatine and BUN before it is contraindicated?   Creatine .6-1.5 (greater than 2.0)BUN 8-25 mg (greater than 45)  
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Name some risk factors for contrast media injection.   renal failure (due to creatine and BUN), allergic reaction, iodine sensitivity  
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cardiovascular changes manifested in response to a contrast medium injection and results in lightheadedness, anxiety, diaphoresis, hypotension and bradycartioa.   Vasovagal  
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If a patient was having a vasovagal reaction what can be done?   give atropine to help  
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What are four mild adverse occurences?   metallic taste, cough, vomitting, flushed, urdicaria  
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what are four severe adverse occurences?   laryngeal edema, cardiac arrest, respiratory arrest, anaphylactic shock  
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Name equipment that should be present in case of a reaction to contrast.   O2, suction, crash cart  
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which drug inhibits vasovagal reactions?   atropine  
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This drug removes excess fluid from body.   lasix  
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Mimics sympathetic system and used in severe contrast reactions.   epinephrine  
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Muscular relaxant and sedative.   valium  
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Phenergan   reduces nausea  
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Benadryl   allergic reaction to contrast  
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If a water soluble contrast was unsafe for myelography what would it have to state?   not for intrathecal injection  
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What are some pharmaceutical routes of administration of medications?   oral, sublingual, rectal, inhalation, parenteral  
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what are 7 parenteral routes of administration?   intradermal, subcutaneous, intramuscular, intra-arterial, intravenous, intrathecal, subarachnoid  
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Give an example of a positive contrast agent.   barium sulfate  
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Give an example of a negative contrast agent.   air  
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Extravasation   leaking into tissues  
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