OT Immunologic disorder
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each of the black spaces below before clicking
on it to display the answer.
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| Cellular immunity | T cells or lymphocytes | Helper induce T cell, cytotoxic or killer t cell, supressor t cell, supressor inducer t cell | (blank) | (blank) | (blank) | (blank)
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| Humoral immunity | B cells or lymphocytes | IgM, IgA,IgG, IgE, IgD | (blank) | (blank) | (blank) | (blank)
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| Tests for cellular immunity | Quantitative ( lymphocyte count, T cell subset (CD4, CD8), NK cell numbers) | Qualitative (DTH skin test, ability to elaborate cytokines ( IL1,2,4, TNF) | Ability to generate MHC-restrict CTL | (blank) | (blank) | (blank)
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| Tests for humoral immune response | serum immunoglobulin levels | determination of isohemagglutinin and febrile agglutinin titers | determination of antibody titers following immunization with tetanus toxoids, diphtheria toxoid, or pneumococcal polysaccharide vaccines | protein electrophoreisis( albumin,globulin,fibrinogen) | immunoelectrophoreisis | (blank)
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| Disorders of immunoglobulin overproduction | MGUS | multiple myeloma | waldenstrom macroglobulinemia | Amyloidosis | heavy chain disease | (blank)
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| Primary Immunologic Difficiency Disorder | selective IgA deficiency | Bruton's X linked, Degeorge thymic hypoplasia | chronic mucocutaneous candidiasis | Wiskott-aldrich syndrome | chronic granulomatous disease (inability tto develope neutrophils | ataxia and aids
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| Secondary Immunologic Difficiency Disorders | AIDS | iatrogenic ( cancer chemotherapy) | immunodificiency associated with Sarcoidosis and Hodgkins | (blank) | (blank) | (blank)
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| Cell mediated autoimmunity | SLE | (blank) | (blank) | (blank) | (blank) | (blank)
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| Antibody-mediated autoimmunity | hemolytic anemia | idiopathic thrombocytopenia | goodpasture's syndrom | grave's disease | myasthenia gravis | type 1 DM
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| Immune complex disease | SLE | rhumatoid arthritis | drug induced hemolytic anemia | drug induced thrombocytopenia | (blank) | (blank)
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| Diagnosis | agglutination of antigen-coated RBC | Enzyme-linked immunoassays (ELISA) | immunoflourescence microscopy | complement fixation | (blank) | (blank)
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| Treatment | supression of autoantibody productions (corticosteroids, cytotoxic agents) | relieve tissue damage from immune complexes (ASA,NSAID,colchine, corticosteroids) | remove offending autoantibodies and circulating immunecomplexes (cytotoxic drugs) | (blank) | (blank) | (blank)
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Created by:
natkat
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