Stack #142010
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| The short clinical duration of action of a single dose of fentanyl is mainly the result of its | A. small volume of distribution
B. large volume of distribution
C. low lipid solubility
D. rapid redistribution
E. short elimination half-life
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| A healthy, obese 110-kg woman is scheduled for gastric stapling. Compared with that required at her ideal body weight, the dose of thiopental required for anesthetic induction would likely be increased because of changes in | A. blood volume B. muscle mass C. circulation time D. body fat E. metabolic rate
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| Compared with epidural morphine, intrathecal morphine produces | A. better relief of visceral pain
B. greater loss of analgesia after administration of naloxone
C. less pruritus
D. less urinary retention
E. more respiratory depression
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| 4. A patient with metastatic carcinoma and chronic renal failure has tremors, fasciculations, mydriasis, and hyperreflexia after several days of therapy with high doses of meperidine for analgesia. Which of the following is most likely to occur if the me | A. Disappearance of symptoms as tolerance to meperidine develops B. Pinpoint constriction of pupils C. Progressive hypothermia D. Progressive sedation from meperidine toxicity E. Seizures from normeperidine toxicity
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| 5. The best premedication regimen for a known heroin addict not acutely under the influence would include | morphine
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| 6. Compared with morphine, a single epidural dose of fentanyl is associated with A. delayed onset of analgesia B. increased incidence of delayed respiratory depression | more restricted segmental spread
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