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Familial Dyslipidemias

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Description
Dyslipidemia
Most common familial dyslipidemia   Type 2a hypercholesterolemia  
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Increased IDL, VLDL, chylomicrons; increased risk of atherosclerosis   Type 3 hyperlipoproteinemia  
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Lipoprotein lipase deficiency   Type 1 hyperchylomicronemia  
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Altered apolipoprotein C-II   Type 1 hyperchylomicronemia  
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Pancreatitis, HSM, eruptive xanthomas, abdominal pain after fatty meals; may lead to retinal vein occlusion   Type 1 hyperchylomicronemia  
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Increased LDL & cholesterol; increased risk of atherosclerosis   Type 2a hypercholesterolemia  
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LDL receptor deficiency   Type 2a hypercholesterolemia  
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Autosomal dominant; corneal arcus, tendon xanthoma, xanthelasma   Type 2a hypercholesterolemia  
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Increased triglycerides, cholesterol, chylomicrons; no increased risk of atherosclerosis   Type 1 hyperchylomicronemia  
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Increased VLDL & triglycerides   Type 4 hypertriglyceridemia  
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Hepatic overproduction of VLDL; pancreatitis   Type 4 hypertriglyceridemia  
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ApoE3/ApoE4 defect   Type 3 hyperlipoproteinemia  
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Created by: kesselmb
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