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Proteins

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Term
Definition
protein(peptide)   nitrogen-containing macronutrient made from amino acids  
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amino acid   nutrient composed of a central carbon bonded to an amino group, carboxylic acid group, and a side-chain group(R-group)  
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peptide bond   a chemical bond that joins amino acids  
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polypeptide   a string of 13+ amino acids held together via peptide bond  
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amino group   the nitrogen-containing component of an amino acid  
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R-group   the portion of an amino acid's structure that distinguishes it from other amino acids  
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alpha-keto acid   a compound that accepts an amino group from an amino acid in the process of transamination  
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transamination   the process whereby an amino group is formed via the transfer of an amino group from one amino acid to another organic compound  
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phenylketonuria(PKU)   an inherited disease in which the body cannot convert phenylalanine into tyrosine  
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complete protein source   a food that contains all the essential amino acids in relative amounts needed by the body  
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incomplete protein source   a food that lacks or contains very low amounts of one or more essential amino acids  
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limiting amino acid   the essential amino acid in the lowest concentration in an incomplete protein source  
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protein complementation   combining incomplete protein sources to provide all of the essential amino acids in relatively adequate amounts  
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high-quality protein source   a complete protein source with high amino acid bioavailability  
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low-quality protein source   a food that id either an incomplete protein source or one that has low amino acid bioavailability  
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genetically modified organism(GMO)   an organism(plant or animal) made by genetic engineering  
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cell signalling   the first step in protein synthesis, in which the cell recieves a signal to produce a protein. Note that this term is also used for a variety of other processes (aside from protein synthesis) within the cell  
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up-regulation   in the context of protein synthesis, increased expression of a gene  
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down-regulation   in the context of protein synthesis, decreased expression of a gene  
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transcription   the process whereby mRNA is made using DNA as a template  
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chromosomes   a strand of DNA and associated proteins in a cell's nucleus  
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gene   a portion of a chromosome that codes for the primary structure of a protein  
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messenger ribonucleic acid(mRNA)   a form of RNA involved in gene transcription  
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translation   the process whereby amino acids are linked together via peptide bonds on ribosomes, using mRNA and tRNA  
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ribosome   an organelle, associated with the endoplasmic reticulum in the cytoplasm, involved in gene translation  
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transfer ribonucleic acid(tRNA)   a form of RNA in the cytoplasm involved in gene translation  
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primary structure   the sequence of amino acids that make up a single peptide chain  
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sickle cell anemia   a disease in which a small change in the amino acid sequence of hemoglobin causes red blood cells to become misshapen and decreases the ability of the blood to carry oxygen and carbon dioxide  
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secondary structure   folding of a protein because of weak bonds that form between elements of the amino acids backbone(not R-groups)  
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alpha-helix   a common configuration that makes up many proteins' secondary structures  
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Beta-folded sheet   a common configuration that makes up many proteins' secondary structures  
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tertiary structure   folding of a polypeptide chain because of interactions among the R-group of the amino acids  
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gene therapy   the use of altered genes to enhance health  
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quaternary structure   the combining of peptide chains with other peptide chains in a protein  
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prosthetic group   a nonprotein component of a protein that is part of the quaternary structure  
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denaturation   the alteration of a protein's 3-D structure by heat, acid, chemicals, enzymes, or agitation  
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genetic makeup   the particular DNA contained in a person's cells  
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mutation   the alteration of a gene  
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polymorphism   an alteration in a gene that is present in at least 1% of the population  
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epigenetics   alterations in gene expression that do not involve changes in the DNA sequence  
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nutrigenomics   the science of how genetics and nutrition together influence health  
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gastrin   a hormone, secreted by endocrine cells in the stomach, which stimulates the production and release of gastric juice  
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pepsinogen   the inactive from(proenzyme) of pepsin, produced in the stomach  
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proenzyme   an inactive precursor of an enzyme  
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pepsin   an enzyme needed for protein digestion  
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protease   an enzyme the cleaves peptide bonds  
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trypsinogen, chymotrysinogen, proelastase, and procarboxypeptidase   inactive proenzymes produced in the pancreas and released into the small intestine in response to CCK  
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trypsin, chymotrypsin, elastase, and carboxypeptidase   active enzymes(proteases) involved in protein digestion in the small intestin  
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food allergy   a condition in which the body's immune system reacts against a protein in food  
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food intolerance   a condition in which the body reacts negatively to a food or food component but does not mount an immune response  
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anaphylaxis   a severe and potentially threatening allergic reaction  
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catalyst   a substance that increases the rate by which a chemical reaction occurs, without being consumed in the process  
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antibody   a protein, produced by the immune system, that helps fight infection  
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albumin   a protein important in regulating fluid balance between intravascular and interstitial spaces  
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edema   the buildup of fluid in the interstitial spaces  
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glucogenic amino acid   an amino acid that can be converted to glucose via gluconeogenesis  
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gluconeogenesis   synthesis of glucose from noncarbohydrate sources  
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deamination   the removal of an amino group from an amino acid  
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protein turnover   the cycle involving both protein synthesis and protein degradation in the body  
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labile amino acid pool   amino acids that are immediately available to cells for protein synthesis and other purposes  
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urea   a relatively nontoxic, nitrogen-containing compound that is produced from ammonia  
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nitrogen balance   the condition in which protein(nitrogen) intake equals protein(nitrogen) loss by the body  
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negative nitrogen balance   the condition in which protein(nitrogen) intake is less than protein(nitrogen) loss by the body  
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positive nitrogen balance   the condition in which protein(nitrogen) intake is greater than protein(nitrogen) loss by the body  
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vegetarian   someone who does not consume any or selected foods and beverages made from animal products  
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lacto-ovo-vegetarian   a type of vegetarian who consumes dairy products and eggs in an otherwise plant-based diet  
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lactovegetarian   a type of vegetarian who consumes dairy products(but not eggs) in an otherwise plant-based diet  
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vegan   a type of vegetarian who consumes no animal products  
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protein-energy malnutrition(PEM)   protein deficiency accompanied by inadequate intake of protein and often of other essential nutrients as well  
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marasmus   a form of PEM characterized by extreme wasting of muscle and adipose tissue  
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kwashiorkor   a form of OEM often characterized by edema in the extremities  
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ascites   abnormal accumulation of fluid in the abdominal cavity  
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