| Question |
Answer |
| Site of production of chylomicron |
Small intestine |
| Site of production of HDL |
Liver |
| Site of production of VLDL |
Liver |
| Process of atherosclerosis |
VLDL "loses" triacylglycerols to tissues -> becomes denser (LDL) -> Too much LDL in the blood -> acumulation of LDL in vessels' walls -> attracts WBC -> plaque formation (stenosis) -> calcium coating -> hardening of the vessel -> atherosclerosis |
| Familial hypercholesterolemia |
Genetic disorder -> LDL receptors don't function properly -> high LDL levels in the blood |
| Enzyme responsible for the transference of membrane cholesterol to HDL |
Flippase |
| Tangier disease |
Flippase genetic disorder -> low HDL levels |
| Transport of cholesterol from intestine to liver |
Chylomicrons |
| Transport of cholesterol from liver to tissues |
VLDL and LDL |
| Transport of cholesterol from tissues to liver (reverse transport) |
HDL |
| Why do atherosclerotic plaques tend to form preferably in the aortic arch? |
High pressure = increased permeability to macromolecules |
Beef Production
