FAS enzymes
| Description: | names and functions of enzymes present in E. coli fatty acid synthase complex |
| Category: | Biochemistry |
| Created by: | phantomkiwi on 2009-05-06 |
| Question | Answer |
| Acyl carrier protein (ACP) | carries acyl groups in thioester linkage |
| Acetyl-CoA-ACP transacetylase(AT) | transfers acyl group from CoA to Cys residue of KS |
| beta-Ketoacyl-ACP synthase(KS) | condenses acyl and malonyl groups (at least 3 isozymes) |
| Malonyl-CoA-ACP transferase(MT) | transfers malonyl group from CoA to ACP |
| beta-Ketoacyl-ACP reductase(KR) | reduces beta-keto group to beta-hydroxyl group |
| beta-hydroxyacyl-ACP dehyratase(HD) | removes H2O from beta-hydroxyacyl-ACP, creating double bond |
| Enoyl-ACP reductase(ER) | reduces double bond, forming saturated acyl-ACP |
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