True or False

Description:	Translation True or False
Category:	Biochemistry
Created by:	P1StudyStack on 2008-12-14

Question	Answer
True or False: The enzyme that synthesizes RNA from a DNA template is DNA polymerase.	False. The enzyme that synthesizes RNA from a DNA template is RNA polymerase.
True or False: The enzyme that synthesizes RNA from a DNA template is RNA polymerase.	True
True or False: RNApol requires an RNA template, rNTPs, and MG++.	False. RNApol requires a DNA template, rNTPs, and Mg++.
True or False: RNApol requires a DNA template, rNTPs, and MG++.	True
True or False: RNApol requires an RNA template, dNTPs, and MG++.	False. RNApol requires a DNA template, rNTPs, and Mg++.
True or False: RNApol requires a DNA template, dNTPs, and MG++.	False. RNApol requires a DNA template, rNTPs, and Mg++.
True or False: Synthesis is always in the 3' to 5' direction.	False. Synthesis is always in the 5' to 3' direction.
True or False: Synthesis is always in the 5' to 3' direction.	True
True or False: RNApol reads the template in the 3' to 5' direction.	True
True or False: RNApol reads the template in the 5' to 3' direction.	False. RNApol reads the template in the 3'to 5' direction
True or False: The free 5'OH of a growing RNA strand attacks the alpha-phosphate of the incoming rNTP.	False. The free 3'OH of a growing RNA strand attacks the alpha-phosphate of the incoming rNTP.
True or False: The free 3'OH of a growing RNA strand attacks the alpha-phosphate of the incoming rNTP.	True
True or False: When the free 3'OH of the growing RNA strand attacks the alpha-phosphate of the incoming rNTP, a phosphodiester bond is formed and pyrophosphate is released.	True
True or False: When the free 5'OH of the growing RNA strand attacks the alpha-phosphate of the incoming rNTP, a phosphodiester bond is formed and pyrophosphate is released.	False. When the free 5'OH of the growing RNA strand attacks the alpha-phosphate of the incoming rNTP, a phosphodiester bond is formed and pyrophosphate is released.
True or False: When the free 3'OH of the growing RNA strand attacks the alpha-phosphate of the incoming rNTP, a glycosidic bond is formed and pyrophosphate is released.	False. When the free 5'OH of the growing RNA strand attacks the alpha-phosphate of the incoming rNTP, a phosphodiester bond is formed and pyrophosphate is released.
True or False: When the free 3'OH of the growing RNA strand attacks the alpha-phosphate of the incoming rNTP, a phosphodiester bond is formed and pyrophosphate is added to the molecule.	False. When the free 5'OH of the growing RNA strand attacks the alpha-phosphate of the incoming rNTP, a phosphodiester bond is formed and pyrophosphate is released.
True or False: Mg++ activates the 5'OH for the nucleophilic attack by the growing RNA strand.	False. Mg++ activates the 3'OH for the nucleophilic attack by the growing RNA strand.
True or False: Mg++ activates the 3'OH for the nucleophilic attack by the growing RNA strand.	True
True or False: The catalytic mechanism of RNA polymerase has 1 Mg++ ion which interacts with the free 3'OH of the growing chain and the alpha-phosphate of the NTP.	False. There are 2 Mg++ ions in the catalytic mechanism of RNA polymerase.
True or False: The catalytic mechanism of RNA polymerase has 2 Mg++ ion which interacts with the free 3'OH of the growing chain and the alpha-phosphate of the NTP.	True
True or False: RNApol has exonuclease activity for proofreading.	False. RNApol does NOT have exonuclease activity for proofreading.
True or False: RNA synthesis in transcription is regulated by specific RNA sequences termed promoters.	False. RNA synthesis in transcription is regulated by specific DNA sequences termed promoters.
True or False: RNA synthesis in transcription is regulated by specific DNA sequences termed promoters.	True
True or False: RNA synthesis in transcription is regulated by specific RNA sequences termed initiators.	False. RNA synthesis in transcription is regulated by specific DNA sequences termed promoters.
True or False: RNA synthesis in transcription is regulated by specific DNA sequences termed initiators.	False. RNA synthesis in transcription is regulated by specific DNA sequences termed promoters.
True or False: In transcription, elongation occurs in fits and starts in both initiation and elongation.	False. Unlike initiation, elongation is a highly processive process in transcription.
True or False: In transcription, elongation occurs in fits and starts in both initiation bu elongation is a highly processive process.	True
True or False: Bacterial mRNA is polycistronic.	True
True or False: Eukaryote mRNA is polycistronic.	False: Eukaryote mRNA is monocistronic. Bacterial mRNA is polycistronic.
True or False: Eukaryote tRNA is polycistronic.	True
True or False: In bacteria, transcription and translation are coupled.	True
True or False: In eukaryotes, transcription and translation are coupled.	False. In eukaryotes transcription takes place in the nucleus and translation takes place in the cytoplasm; the two processes are uncoupled.
True or False: In eukaryotes transcription takes place in the nucleus and translation takes place in the cytoplasm; the two processes are uncoupled.	True