| Question |
Answer |
| Inhibits complex III (Cytochrome c reductase) of the ETC |
Antimycin A |
| Inhibits ATP translocase |
Aphidicolin |
| Prevents ATP production by phosphoglycerate kinase |
Arsenate |
| Irreversible inhibitor of COX-1 |
Aspirin |
| Inhibits CPSII, CTP synthetase and PRPP amidotransferase |
Azaserine |
| Inhibits carbamoyl phosphate synthetase II |
Azaserine |
| Chain terminators to inhibit viral DNA repliation |
AZT and didanosine |
| Inhibits Complex IV (Cytochrome oxidase) of the ETC |
Cyanide, CO, Azide (N3) |
| Inhibits Na+/K+-ATPase |
Digoxin |
| Covalently modifies eEF2, inactivates it and inhibits translation |
Diptheria toxin |
| Inhibits Type II topoisomerase in humans |
Etoposide |
| Inhibits enolase |
Flourine |
| Suicide inhibitor of thymidylate synthase |
Fluorouracil |
| Inhibits thymidylate synthase |
Fluorouracil |
| An anticancer drug that is a suicide inhibitor of thymidylate synthetase |
Fluorouracil |
| This anticancer drug inactivates thymidylate synthetase and therefore inhibits DNA synthesis. |
Fluorouracil |
| Effective in the treatment of DVT because it acts to inhibit the activity of thrombin |
Heparin |
| Used in the treatment of tuberculosis, this reacts with pyridoxal leading to a B6 deficiency |
Isoniazid |
| Inhibits de novo synthesis of purines, thereby inhibitin DNA synthesis. |
Mercaptopurine |
| Inhibits aspartate transcarbamoylase (the pyrimidine biosynthetic enzyme) and prevents DNA replication |
N-phosphonacetyl-L-aspartate) PALA |
| Irreversible inhibitor of transpeptidase involved in cell wall synthesis |
Penicillin |
| These three enzymes inhibit DNA gyrase and prevent the growth of E. coli |
Quinolones, nalidixic acid and ciprofloxacin |
| Hydrolyzes 28S RNA and inactivates ribosomes |
Ricin |
| Ligand for estrogen receptor |
Tamoxifen |
| Vitamin K analog that inhibits the regeneration of Vitamin K |
Warfarin (Coumadin) |
| Antibacterial agents which competitively inhibit digydropteroate synthase |
Sulfonamides |
| Inhibits dihydrofolate recuctase (DHFR) |
Trimethoprim |
| Inhibits ATP Synthase |
Oligomyacin |
Science Vocab 147928
