Question | Answer |
Transgentic | The transfer of genes between species |
Transgentic organism | An organism that has received a gene from another species by means of recombinant DNA technology |
Pompe disease | An inability to make a -gluvosidase, leads to reduced heart and muscle function |
Transgentic animals produce human GAA example | Transgenic F rabbits produce human GAA enzyme in their milk, and in transgenic hamster cells |
Embryonic Stem Cells | From the inner cell mass of early embryos. These cells and pluripotent and can form many different mature cell types |
Adult Stem Cells | Recovered from bone marrow or other organs. Can develop into a limited number of mature cells. Are considered multipotent |
Induced plutipotent stem cells | Adult cells reprogrammed by gene transfer. They behave similar to embryonic stem cells. |
Stem cell uses | Can replace defective cells, treatment of leukemia, treatment of burns |
Diseases studied with stem cells | Huntington's, Gaucher, Type 1 diabetes |
Minisatellites | Nucleotide sequences 14-100 base pairs long, organized into cluster of varying lengths; used in the construction of DNA fingerprints |
DNA fingerprint | Detection of variations in minisatellites used to identify individuals |
Short Tandem Repeat | Short nucleotide sequences 2-9 base pairs long organized into cluster of varying lengths |
DNA profile | STR pattern used to identify individuals |