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Chapter 14 GENE

Genetics Chapter 14 Human Heredity

Transgentic The transfer of genes between species
Transgentic organism An organism that has received a gene from another species by means of recombinant DNA technology
Pompe disease An inability to make a -gluvosidase, leads to reduced heart and muscle function
Transgentic animals produce human GAA example Transgenic F rabbits produce human GAA enzyme in their milk, and in transgenic hamster cells
Embryonic Stem Cells From the inner cell mass of early embryos. These cells and pluripotent and can form many different mature cell types
Adult Stem Cells Recovered from bone marrow or other organs. Can develop into a limited number of mature cells. Are considered multipotent
Induced plutipotent stem cells Adult cells reprogrammed by gene transfer. They behave similar to embryonic stem cells.
Stem cell uses Can replace defective cells, treatment of leukemia, treatment of burns
Diseases studied with stem cells Huntington's, Gaucher, Type 1 diabetes
Minisatellites Nucleotide sequences 14-100 base pairs long, organized into cluster of varying lengths; used in the construction of DNA fingerprints
DNA fingerprint Detection of variations in minisatellites used to identify individuals
Short Tandem Repeat Short nucleotide sequences 2-9 base pairs long organized into cluster of varying lengths
DNA profile STR pattern used to identify individuals
Created by: tstrange