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Paramedic_K
Drugs
Question | Answer |
---|---|
Epinephrine_Class | Sympathomimetic |
Epinephrine_Mechanism of Action | Direct acting alpha and beta agonist. Alpha: vasoconstriction. Beta 1: positive inotropic, chronotropic and dromotropic effects. Beta 2: bronchial smoothe muscle relaxation and dilation of skeletal vasculature. |
Epinephrine_Indications | Cardiac arrest (V-fib/pulseless V tach, asystole, PEA) symptomatic bradycardia as an alternative infusion to dopamine, sever hypotension secondary to bradycardia when atropine and transcutaneous pacing are unsuccessful |
Epinephrine_Indications Pt 2 | symptomatic bradycardia as an alternative infusion to dopamine, sever hypotension secondary to bradycardia when atropine and transcutaneous pacing are unsuccessful, allergic reactions, anaphylaxis, asthma. |
Epiniphrine_Contraindications | Hypertension, hypothermia, pulmonary edema, myocardial ischemia, hypovolemic shock |
Epinephrine_Adverse Reactions | Hypertension, tachycardia, arrhythmias, pulmonary edema, anxiety restlessness, psychomotor agitation, nausea, headache, angina |
Epinephrine_Drug Interactions | Potentiates other sympathomimetics, deactivated by alkaline solutions (ie. sodium bicarbonate), monamine oxidase inhibitors (MAOIs) may potentiate effects, beta blockers may blunt effects. |
Epinephrine_How Supplied | 1:1,000 solution: ampules and vials containing 1mg/mL. 1:10,000 solution: prefilled syringes containing 1 mg in 10 mL (0.1 mg/mL). Auto-injector (EpiPen): 0.5 mg/mL (1:2,000) |
Epinephrine_Dosage and Administration ADULT | ADULT: Mild allergic reactions and asthma: 0.3-0.5 mg (0.3-0.5 mL of 1:1,000)SC. Anaphylaxis: 0.1 mg (1 mL of 1:10,000) IV/IO over five minutes. |
Epinephrine_Dosage and Admin: CARDIAC ARREST ADULT | Cardiac Arrest: IV/IO dose: 1 mg (10 mL of 1:10,000 solution} every 3-5 minutes during rescitation. Follow each dose with 20mL flush, elevate arm for 10 to 20 seconds after dose. Higher dose: Higher doses up to .2 mg/kg may be used for specific conditions |