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Biochemistry 2 E3,3
Biochemistry 2 Palmer Exam 3 Pentose Phosphate Pathway
| Question | Answer |
|---|---|
| pentose phosphate pathway produces | ribose 5 phosphate |
| hexose monophosphate pathway starts with | glucose 6 phosphate |
| the pentose phosphate pathway makes what | ribose and NADPH |
| the main emzyme for the pentose phosphate pathway is what | glucose 6 phosphate dehydrogenase |
| what is the location of the hexose monophophate pathway | cytosol |
| hexose monophosphate pathway makes | 2NADPH and glucose 6 phosphate |
| what would stimulate building new cells | glucose 6 phosphate dehydrogenase |
| anything that consumes ribose stimulates | pentose phosphate pathway |
| what are the 4 things for NADPH utilization | 1)reductive biosynthesis 2)detoxification 3)respiratory bursts 4)antioxidant regeneration |
| what is reductive biosynthesis | building things by adding electrons -fat, cholesterol, steroid hormones, bile salts |
| what is detoxification | making toxins more water soluble for excretion by adding electrons from NADPH -toxins are then excreted by urine -adding OH to make molecules more H2O soluble |
| what is respiratory bursts | creating "harsh chemistry" to kill bad guys by using electrons from NADPH -white blood cells take more O2 "respiratory burst" -O2 and e- make very reactive molecules(harsh chemistry) -reactive molecules are sequestered in a vesicle where the bacteria d |
| what is antioxidant regeneration | adding electrons from NADPH to antioxidants so they can keep protecting the body from free radicals -reactive molecules are inactivated by antioxidants, NADPH gives antioxidants electrons |
| substance that inhibits oxidation and is capable of counteracting the damaging effects of oxidation in body tissue | antioxidant |
| atom or molecule that has one or more unpaired electrons | free radical |
| common radicals/reactive species | 1)O2- superoxide 2)H2O2 hydrogen peroxide 3).OH hydroxyl |
| process by which electronically excited molecules are inactivated | quenching |
| process by which the antioxidant's reducing power is restored | regeneration |
| antioxidants give electrons to | free radicals |
| what is the function of superoxide dismutase | 1)eliminate superoxide 2)produce hydrogen peroxide |
| anything that consumes NADPH stimulates | pentose phosphate pathway |
| what are the key enzymes for the pentose phosphate pathway | 1)glucose 6 phosphate dehydrogenase 2)superoxide dismutase 3)catalase 4)glutathione peroxidase 5)myeloperoxidase 6)cytochrome P-450 mono-oxygenase system |
| what are the 2 products of pentose phosphate pathway | ribose and NADPH |
| ribose is sugar for what | 1)DNA 2)RNA 3)ATP 4)CoA 5)NAD 6)FAD |
| NADPH is reducing power for | 1)reductive biosynthesis 2)detoxification 3)respiratory burst 4)antioxidant |
| what is the enzyme for the pentose phosphate pathway | glucose 6 phosphate dehydrogenase |
| what is G6P dehydrogenase stimulated by | 1)NADP 2)building new cells -reductive biosynthesis -antioxidant regeneration -WBC respiratory bursts -detoxification |
| what is G6P dehydrogenase inhibited by | 1)NADPH 2)ribose 3)AMP, ADP (low energy) |
Created by:
ellerjason12
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