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Pathology Cumulative

ABFSE Glossary and Textbook

a decrease in, such as pain abatement
an excoriation, a circumscribed removal of the epidermis of skin or mucous membrane abrasion
a circumscribed collection of pus abscess
a marked decrease in blood carbon dioxide content acapnia
condition in which there is an excessive proportion of acid in the blood acidosis
a disease which is not congenital, but has developed since birth acquired disease
a disease or ailment which is sharp and of short course acute
a neoplasm formed by glandular epithelium adenoma
condition in which there is an excessive proportion of alkali in the blood alkalosis
a pre-senile dementia occurring usually in persons over 60 years of age; thought to be associated with neurofibril degeneration alzheimer's disease
congenital absence of the extremities amelia
a decrease in red blood cells, hemoglobin, or both anemia
generalized massive edema in subcutaneous tissue anasarca
blood-filled saclike dilation of the wall of an artery aneurysm
congenital absence of an organ or other part-in hematology, incomplete or defective development or a cessation of regeneration aplasia
a swelling or tumor due to dilatation of blood vessels (hemangioma) or lymphatics (lymphangioma) angioma
deficient blood oxygen supplies to tissues anoxia
accumulation of serous fluid in the abdominal cavity ascites
inflammation, usually of a chronic progressive character, involving an artery or arteries arteritis
hardening of the arteries arteriosclerosis
loss of consciousness from deficient oxygen asphyxia
arteriosclerosis or hardening of the artery walls characterized by lipid deposits in the tunica intima atherosclerosis
wasting away of tissue, decrease in size of part atrophy
postmortem examination of the organs and tissues of a body to determine cause of death or pathological condition autopsy
a tearing away avulsion
the red pigment in the bile bilirubin
the green pigment in the bile biliverdin
pre-embalming purge as a result of skull fracture, surgical procedure in the cranial cavity, or trauma-can also manifest as gas buildup which can bulge the eyes brain purge
a general state of ill-health associated with emaciation cachexia
a general term for a malignant tumor carcinoma
several communicating boils of the skin and subcutaneous tissues with the production and discharge of pus and dead tissue carbuncle
formation of cavities in an organ or tissue, frequently seen in some forms of tuberculosis cavitation
deterioration of an organ or cell structure which may include swelling cellular degeneration
cellular reaction to injury which may include swelling cellular infiltration
a blow, a paralytic or apoplectic stroke or apoplexy cerebral vascular accident (CVA)
primary lesion, initial sclerosis, syphilitic sore-the first manifestation of syphilis chancre
inflammation of the gallbladder cholecystitis
a disease of slow progress and long continuance chronic
a degeneration of the parenchyma cells of an organ with hypertrophy of the interstitial connective tissue: ex: liver cirrhosis
inflammation of the mucous membrane of the colon colitis
any disease which is transmitted by infection or contagious directly or though the agency of a vector communicable
a bruise often accompanied with swelling contusion
a congenital condition due to hypothyroidism resulting in mental retardation cretinism
condition in which the descent of a testis into the scrotum is arrested at some point in the normal path cryptorchism
bluish appearance of the skin from deficient oxygenation of the blood cyanosis
abnormal sac containing gas, fluid, or a semi-solid material cyst
inflammation of the bladder, especially the urinary bladder cystitis
a chemical reaction involving breakdown of chemical bonds, forms two or more smaller molecule compounds from larger molecule compounds decomposition
disease due to lack of dietary or metabolic substance deficiency
term used to designate two diseases, each having the symptom of polyuria in common (name the two versions of this disease) diabetes insipidus and mellitus
the determination of the nature of a disease diagnosis
presence of a number of diverticula in the intestine diverticulosis
results when the body part that dies has little blood and remains aseptic and occurs when the arteries but not the veins are obstructed dry gangrene
abnormal tissue development dysplasia
faulty nutrition dystrophy
purplish patch caused by extravasation of blood into the skin, a black and blue spot ecchymosis
displaced, not in the normal place, for example: an extrauterine pregnancy ectopic
excessive fluid in the tissues (two terms) edema, dropsy
extreme loss of flesh, growing lean emaciation
obstruction of a blood vessel by foreign matter carried into the bloodstream embolism
inflammation of the brain encephalitis
denotes a disease which prevails more or less continuously in a region endemic
inflammation of the living membrane of the heart endocarditis
inflammation of the mucous membrane of the cervix uteri endocervicitis
ectopic occurrence of endometrial tissue or its diffuse implantation or infiltration in the myometrium endometriosis
pus in the pleural cavity empyema
inflammation of the intestine enteritis
a disease attacking a considerable number of people in a community simultaneously epidemic
nosebleed epistaxis
inflammation of the esophagus esophagitis
doctrine of causes, specifically the causes of disease etiology
a sudden increase in the severity of a disease exacerbation
a product of inflammation exudates
relating to fever, feverish febrile
encapsulated tumor composed mainly of fibrous connective tissue fibroma
abscess or pyogenic infection of a sweat gland or hair follicle furuncle
form of necrosis combined with putrefaction gangrene
inflammation of the stomach gastritis
inflammation of the gums gingivitis
parenchymatous nephritis with pronounced lesions in the glomeruli glomerulonephritis
chronic enlargement of the thyroid gland, due to iodine deficiency goiter
study of changes in the body that are readily seen with the unaided eye as a result of a disease gross pathology
vomiting of blood hematemesis
blood cyst, a tumor containing effused blood hematoma
passage of blood in the urine hematuria
blood in the sputum hemoptysis
hemorrhagic disease characterized by a tendency to excessive and sometimes spontaneous bleeding hemophilia
bleeding, a flow of blood, especially if profuse hemorrhage
inflammation of the liver hepatitis
serous fluid in the scrotum hydrocele
dilatation of the pelvis and calyces of one or both kidneys in consequence of obstruction of the flow of urine hydronephrosis
abnormal accumulation of fluid within the pericardial sac hydropericardium
serous fluid in the pleural cavity hydrothorax
increased amount of blood in a part, congestion hyperemia
increased size of a part from an increase in the size of its cell hypertrophy
defective formation, incomplete development of a part hypoplasia
a disease that is caused by the medical profession iatrogenic
a disease without a recognizable cause idiopathic
foreign or heterogeneous substance contained in a cell or in any tissue or organ that was not introduced as a result of trauma inclusions
formation of an area of necrosis in a tissue caused by obstruction in the artery supplying the area infarction
harboring of animal parasites infestation
seepage or diffusion of substances into tissues that are not ordinarily present infiltration
tissue reaction to irritation, infection, or injury marked by localized heat, swelling, redness, pain, and sometimes loss of function inflammation
state of being poisoned by a drug or toxic substance intoxication
local anemia, temporary lack of blood supply to an area ischemia
yellow staining of the integument and deeper tissue with bile pigments jaundice
a tear or torn wound laceration
specific pathologic structural and functional changes or both brought about by disease lesion
organ of detoxification and bile production liver
increase in white blood cells in the body leukocytosis
disease characterized by the appearance of great numbers of immature and abnormal white blood cells leukemia
abnormally low white blood cell count leukopenia
tumor composed of fatty tissue lipoma
malignancy of lymphoid tissue lymphoma
defect or deformity malformation
study of disease to ascertain cause and manner of death medicolegal pathology
malignant pigmented mole melanoma
black tarry feces melena
replacement of one type of tissue into a form that is not normally found there metaplasia
inflammation of the membranes of the brain or spinal cord meningitis
spread of tumor cells from one part of the body to another by blood or lymph metastasis
study of microscopic changes that cells, tissues, and organs undergo as a result of disease microscopic pathology
another term for microscopic pathology histopathology
necrotic tissue that results from inadequate venous drainage, may be accompanied by invasion of saprophytic bacteria moist (wet) gangrene
relative incidence of a disease in the population or number of cases in a given time in a given population morbidity rate
ration of the number of deaths to the total population mortality rate
chronic disease of the nervous system characterized by remissions and relapses and the presence of patches of demyelination with hardening scattered throughout the grey and white matter of the brain stem and spinal cord multiple sclerosis
inflammation of the spinal cord or of the bone marrow myelitis
heart attack, results in damage to the myocardium myocardial infarction
inflammation of the muscle walls of the heart myocarditis
pathological death of cells in a still-living organism necrosis
abnormal, excessive and uncontrollable multiplication of cells with the formation of a mass or new growth of tissue neoplasm
renal calculus or gravel nephrolithiasis
infection acquired in a hospital nosocomial
diminished amount of urine production oliguria
disease marked by softening of the bone due to faulty calcification in adulthood osteomalacia
inflammation of the bone and bone marrow osteomyelitis
inflammation of an ovary oophoritis
bone tumor osteoma
loss of bone density osteoporosis
bony tumor containing many imperfectly differentiated, vegetative, or embryonic cells osteosarcoma
disease affecting all of a population, a worldwide epidemic pandemic
overgrowth or hypertrophy of the papillae of a cutaneous or mucous surface papilloma
paralysis agitans parkinson's disease
the manner in which a disease develops pathogenesis
study of structural changes in the body caused by disease pathological anatomy
ulcer of the mucous membrane of the stomach or duodenum, caused by gastric juice peptic ulcer
inflammation of the pericardium pericarditis
inflammation of the lining of the abdominal cavity peritonitis
small pinpoint hemorrhages petechiae
inflammation of the pharynx pharyngitis
inflammation of a vein phlebitis
congenital condition in which the proximal portions of limbs are poorly developed or absent phocomelia
inflammation of the pleura pleuritis
increase in total red blood cell mass polycythemia vera
any prolonged inhalation of mineral dust pneumoconiosis
infection of the lungs pneumonia
forecast of the outcome of a disease prognosis
copious evacuation from body surfaces purge
hemorrhage of the skin and mucous membranes purpura
small circumscribed pus elevation pustule
inflammation of the pelvis of the kidney pyelitis
disease that reappears after a period of remission recurrent disease
lessening in severity/temporary abatement of a disease remission
kidney stones renal calculi
physical/mechanical restoration of damaged tissue by the growth of new or healthy cells repair
inflammation of the nasal mucous membrane rhinitis
disease of infants and children-deficiency of vitamin D, causing defective bone growth rickets
inflammation of the fallopian tube salpingitis
inflammation of the sinus cavities sinusitis
defect in the spinal column, spinal membranes protrude spina bifida
narrowing of any canal, especially a cardiac canal stenosis
formation of pus suppuration
study of tissue specimens excised surgically in a major or minor operation surgical pathology
a concurrence of symptoms syndrome
formation of a clot thrombosis
an open sore or lesion of skin or mucous membrane accompanied by sloughing of inflamed necrotic tissue ulcer
excess of urea and other nitrogenous waste in the blood uremia
inflammation of the ureters ureteritis
inflammation of the urethra urethritis
inflammation of the vagina vaginitis
failure of a heart valve to close tightly, allowing regurgitation of blood valvular insufficiency
blister-like elevation of skin containing serous fluid vesicle
hyperfunction of pituitary gland after ossification has been completed acromegaly
having a hypersensitivity to a substance that does not normally cause a reaction allergies
congenitally malformed palate with a fissure along the midline cleft palate
study of disease by means of body secretions, excretions, and other body fluids performed in the laboratory in the diagnosis of a disease clinical pathology
an unfavorable condition arising during the course of disease complication
the immediate and temporary disturbance of brain function concussion
existing at the time of birth or shortly thereafter congenital
accumulation of an excess of blood or tissue in a body part congestion
the deterioration of tissues with corresponding functional impairment as a result of disease or injury degeneration
loss of moisture from body tissue which may occur antemortem or postmortem dehydration
the condition of the heart being enlarged, occurring normally, artificially or as a result of disease dilatation
chronic neurogenic disease marked by sudden alterations in consciousness and frequently by convulsions epilepsy
loss of blood to the point where life can no longer be sustained exsanguination
a disease having a rapid and severe onset, usually fatal fulminating
a condition/disease in which there is no recognizable change in anatomy functional
deals with the study of the widespread processes of disease such as inflammation, degeneration, necrosis, or cellular death, repair, etc without reference to particular organs or organ systems general pathology
genetic characteristics transmitted from parent to offspring hereditary
abnormal protrusion of a part of an organ through an abnormal opening in the wall that normally contains it hernia
excessive accumulation of cerebrospinal fluid in the ventricles of the brain hydrocephalus
the increase in the size of an organ or part due to the excessive but regulated increase in the number of its cells hyperplasia
state in which the body is invaded by a pathogenic agent that under favorable conditions multiplies and produces injurious effects infection
extravasation of blood within the skull intracranial hemorrhage
disease with an abnormally high rate of occurrence in members of the workforce occupational disease
condition/disease in which there is a specific change in anatomy organic
the science that deals with the study of disease pathology
study of changes in body functions due to disease physiological pathology
coloration caused by deposit, or lack, of colored material in the tissues pigmentation
contagious infectious disease of the spinal cord caused by a filterable virus poliomyelitis
growth or mass of tissue that protrudes from a mucous membrane polyp
number of cases of disease present in a specified population at a given time prevalence
inflammation of the prostate gland prostatitis
replacement of damaged cells with identical cells regeneration
termination of the inflammatory response with the affected part returning to its normal state resolution
objective disturbances produced by disease, observable ex: ever, pulse, heart rate signs
deals with the specific features of disease in relation to particular organs or organ systems special pathology
disease that occurs occasionally in a random or isolated manner sporadic
subjective disturbances caused by disease that are felt by the patient, but not objectively measurable Ex: pain, headache symptoms
implantation and development of the fertilized ovum in a uterine tube tubal pregnancy
physiological derangement produced by the cause of death that results in death mechanism of death
explains how the cause of death came about manner of death
process or event leading to an injury or wound trauma
body temperature below 80 degrees fahrenheit hypothermia
waxy translucent complex protein, causes waxy degeneration amyloid
depositing of calcium salts, magnesium, iron, and other minerals within the cells calcification
common form of arthritis that causes swelling and pain in some of the body's joints, due to accumulation of excess amounts of uric acid in the tissues gout
necrosis with cheeselike exudate caseous necrosis
birth defect defined as the presence of one or more extra fingers or toes polydactylism
decrease in the diameter of a blood vessel vasoconstriction
the movement of white blood cells to an area of inflammation in response to the release of chemical mediators by lymphocytes chemotaxis
process in which macrophages engulf and destroy antigens phagocytosis
edema usually of the skin of the extremities, when pressed firmly with a finger, the skin maintains the depression pitting edema
accumulation of fluid in the lungs, may inhibit gas exchange pulmonary edema
non-cancerous tumors benign
cancerous tumors malignant
benign neoplasm of epithelial lining of glands/ducts adenoma
benign neoplasm of melanocytes nevus
benign neoplasm of mucous membranes polyp
benign neoplasm of blood vessel endothelium hemangioma
benign neoplasm of bone osteoma
benign neoplasm of cartilage chondroma
benign neoplasm of fat lipoma
benign neoplasm of fibrous connective tissue fibroma
benign neoplasm of striated muscle rhabdomyoma
benign neoplasm of smooth muscle leiomyoma
benign neoplasm of nerves neuroma
malignant neoplasm of melanocytes melanoma
malignant neoplasm of stratified squamous cells squamous cell carcinoma
malignant neoplasm of epithelial lining of glands/ducts adenocarcinoma
malignant neoplasm of urinary tract epithelium transitional cell carcinoma
malignant neoplasm of basal cells of skin basal cell carcinoma
malignant neoplasm of blood vessel endothelium hemangiosarcoma
malignant neoplasm of bone osteosarcoma
malignant neoplasm of cartilage chrondrosarcoma
malignant neoplasm of fat liposarcoma
malignant neoplasm of fibrous connective tissue fibrosarcoma
malignant neoplasm of lymph vessels lymphangiosarcoma
malignant neoplasm of striated muscle rhabdomyosarcoma
malignant neoplasm of smooth muscle leiomyosarcoma
malignant neoplasm of the brain glioma
anemia caused by improper growth or impaired function of bone marrow aplastic anemia
anemia resulting from the hemolysis of red blood cells prematurely hemolytic anemia
anemia caused by a failure of the body to produce enough intrinsic factor (B12 vitamin deficiency) pernicious anemia
anemia characterized by crescent-shaped red blood cells sickle cell anemia
erythrocytosis is another name for this blood condition polycythemia vera
hemophilia due to lack of blood clotting factor VIII hemophilia A
hemophilia due to a lack of factor IX, also known as hemophilia B, Christmas disease
severely reduced platelet count in the blood thrombocytopenia
blood disorder where there is an incompatibility of blood factors from mother to fetus erythroblastosis fetalis
shortness of breath dyspnea
quivering or spontaneous contraction of the individual cardiac cells fibrillation
loss of the normal beating pattern of the heart arrhythmia
the chest pain associated with heart attacks angina
high blood pressure hypertension
foramen ovale fails to properly close at birth atrial septal defect
disease characterized by the narrowing of the lumen of the coronary arteries due to atherosclerosis coronary artery disease
enlarged tortuous veins close to the skin's surface varicose veins
inflammation of the colon colitis
inflammation of the vermiform appendix appendicitis
inflammation of the gall bladder cholecystitis
inflammation of the pancreas pancreatitis
inflammatory bowel disease which is caused by scar tissue formation in the intestines Crohn's disease
another name for jaundice icterus
rare form of diabetes that affects the liver's ability to metabolize iron, causing enlargement of the liver and a bronze discoloration of the skin bronze diabetes
a deficiency in the adrenocortical hormone production which causes a bronze skin discoloration Addison's disease
characterized by one part of the intestine slipping into a previous segment of the intestine (two terms) intussusception, invagination
caused when the bowel twists onto itself, causing obstruction volvulus
condition in which the bronchi are hypersensitive to stimuli asthma
coal worker's pneumoconiosis black lung disease
inhalation of crystalline silica causes silicosis
inhalation of asbestos causes asbestosis
inhalation of beryllium dust causes berylliosis
loss of lung volume due to inadequate expansion of the air spaces, results in inadequate gas exchange in the lungs atelectasis
chronic inflammatory disease of the respiratory system characterized by the presence of air pockets at the terminal ends of the bronchioles emphysema
fatal genetic respiratory disease where cells produce a thick, sticky mucus that clogs the lungs cystic fibrosis
respiratory disorder in which the bronchioles become occluded and the alveolar sacs become dehydrated chronic obstructive pulmonary disease
inflammation of the kidney and the nephron pyelonephritis
inflammation of the renal pelvis of the kidney pyelitis
general name for kidney disease Bright's disease
a process of diffusing blood across a semipermeable membrane to remove toxic materials dialysis
fatal neurological disease motor neuron disease also known as Lou Gehrig's disease ALS (amyotrophic lateral sclerosis)
bleeding between the dura mater and the skull extradural hematoma
bleeding between the dura mater and the arachnoid membrane subdural hematoma
bleeding between the pia mater and the arachnoid membrane subarachnoid hematoma
the occurence of seizures during pregnancy eclampsia
the abnormal growth of prostate cells, non cancerous benign prostatic hyperplasia
inflammation of the bursa in certain joints of the body bursitis
genetic disorder of bone growth causing dwarfism achondroplasia
developmental disorder of the spine in which the spinal column exhibits a lateral curvature scoliosis
excessive growth (hyperplasia) of the bones of the elderly causing chronic inflammation, thickening, and softening of the bones Paget's disease
insulin-dependent diabetes type I
non-insulin-dependent diabetes type II
diabetes which is caused by a disorder of the pancreas diabetes mellitus
diabetes caused by a disorder between the pituitary gland and the kidneys diabetes insipidus
clinical manifestations of hypothyroidism that includes gelatinous substance infiltrating the skin giving a waxy or coarsened look myxedema
hyperthyroidism caused by an autoimmune attack on the thyroid gland, leading cause of hyperthyroidism Graves disease
iatrogenic disorder of the adrenal glands due to chronic glucocorticoid hormone therapy-excess cortisol Cushing's syndrome
failure of the adrenal glands to secrete appropriate levels of corticosteroids due to bleeding within the adrenal cortex Waterhouse-Friderichsen Syndrome
chronic inflammatory disease of the skin characterized by red, thickened areas with silvery scales psoriasis
general term for any number of inflammatory skin conditions eczema
idiopathic disorder in which melanocytes stop producing pigment and are destroyed, results in white patchy spots on the affected part vitiligo
inflammatory disorder of the lymph vessels characterized by local and systemic pain lymphangitis
enlargement of the spleen beyond its normal size splenomegaly
enlargement of the lymph nodes lymphadenopathy
cancer of the lymphatic system lymphoma
lymphoma with the presence of Reed-Sternberg cells (malignant abnormality of a B lymphocyte) Hodgkins lymphoma
lymphoma which is a collection of many varied lymphomas non-Hodgkins lymphoma
anemia characterized by decrease in production of red blood cells primary anemia
anemia characterized by increase in destruction of red blood cells secondary anemia
most common form of leukemia in children ALL
Created by: amyziolkowski